Short allele of serotonin transporter gene promoter is a risk factor for obesity in adolescents

Obesity and hypertension are increasing medical problems in adolescents. Serotonin transporter (5-HTT) is involved in mood and eating disturbances. Encoded by the gene SLC6A4, the promoter shows functional insertion/deletion alleles: long (L) and short (S). Because individuals who are carriers for the short version are known to be at risk for higher levels of anxiety, we hypothesized that this variant may be associated with overweight. Data and blood samples were collected from 172 adolescents out of a cross-sectional, population-based study of 934 high school students. To replicate the findings, we also included 119 outpatients from the Nutrition and Diabetes Section of the Children's County Hospital. We found that the S allele was associated with overweight (BMI > 85th percentile), being a risk factor for overweight independently of sex, age, and hypertension [odds ratio (OR): 1.85; 95% confidence interval (CI): 1.13, 3.05; p < 0.02]. Additionally, in the outpatient study, compared with the homozygous LL subjects, S allele carriers showed a higher BMI z-score (1.47 +/- 1.09 vs. 0.51 +/- 1.4; p < 0.002) and were more frequent in overweight children. In conclusion, the S allele of the SLC6A4 promoter variant is associated with overweight being an independent genetic risk factor for obesity.     

Aerobiological survey in L'Aquila (Italy) throughout 1988 to 1990

Summary Airborne pollens were sampled in L'Aquila (Italy) throughout 1988 to 1990. Our data indicate that the flowering seasons of pollens mostly accounting for airborne concentrations are somewhat unique as compared to other Mediterranean areas. The prolonged season of Cupressaceae as well as the two different flowering seasons of Oleaceae, namely ofFraxinus, Ligustrum andOlea europaea, respectively, were the most relevant findings of our study. Furthermore, it is also worth to note thatParietaria judaica could be detected during the study period throughout March to June, but not in late summer and early autumn, as expected.Moreover, we evaluated the frequency of different pollen sensitizations in 2813 patients requiring medical care during the study period because of allergic diseases, such as conjunctivitis, oculorhinitis, and bronchial asthma. Our data demonstrate that both Compositae and Urticaceae proved to be the most allergenic pollens despite the low airborne concentrations detected. Finally, a relevant finding was the highOlea sensitization among patients with bronchial asthma.     

Minnow introductions in mountain lakes result in lower salmonid densities

Biological Invasions - Small fish species such as minnows (Phoxinus sp.) are introduced into mountain lakes by anglers that use them as live bait for fishing salmonids that were previously...