Excitation-inhibition imbalance disrupts visual familiarity in amyloid and non-pathology conditions

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Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4

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Entropic Bristles Tune the Seeding Efficiency of Prion-Nucleating Fragments

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C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation

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Conformational Priming of RepA-WH1 for Functional Amyloid Conversion Detected by NMR Spectroscopy

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Transcriptional Signatures of Tau and Amyloid Neuropathology

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High-resolution structure and strain comparison of infectious mammalian prions

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Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases

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SYK coordinates neuroprotective microglial responses in neurodegenerative disease

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hnRNPDL Phase Separation Is Regulated by Alternative Splicing and Disease-Causing Mutations Accelerate Its Aggregation

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Staphylococcus aureus PSMα3 Cross-α Fibril Polymorphism and Determinants of Cytotoxicity

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Dynamics of the normal gut microbiota: A longitudinal one-year population study in Sweden

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Computational Modeling of Protein Stability: Quantitative Analysis Reveals Solutions to Pervasive Problems

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AMPK-mediated phosphorylation on 53BP1 promotes c-NHEJ

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Evidence for a clathrin-independent endocytic pathway for APP internalization in the neuronal somatodendritic compartment

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Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens

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Reshaping endoplasmic reticulum quality control through the unfolded protein response

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Dephosphorylation of the pre-initiation complex is critical for origin firing

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Evolutionary history of Staphylococcus aureus influences antibiotic resistance evolution

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Substrate-binding guides individual melibiose permeases MelB to structurally soften and to destabilize cytoplasmic middle-loop C3

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