Computational Modeling of Protein Stability: Quantitative Analysis Reveals Solutions to Pervasive Problems

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PDBcor: An automated correlation extraction calculator for multi-state protein structures

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WNK1 is an assembly factor for the human ER membrane protein complex

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Disease-linked mutations cause exposure of a protein quality control degron

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Characterization of synthetic antigen binding fragments targeting Toc75 for the isolation of TOC in A. thaliana and P. sativum

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PDB-wide identification of physiological hetero-oligomeric assemblies based on conserved quaternary structure geometry

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Sensing of a spore surface protein by a Drosophila chemosensory protein induces behavioral defense against fungal parasitic infections

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A “spindle and thread” mechanism unblocks p53 translation by modulating N-terminal disorder

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Mechanism of signal-anchor triage during early steps of membrane protein insertion

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Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding

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Proteome-wide mapping of short-lived proteins in human cells

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Pre-emptive Quality Control of a Misfolded Membrane Protein by Ribosome-Driven Effects

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Functional and Regulatory Roles of Fold-Switching Proteins

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Structural Insights into of the Allosteric Activation of the LicT Antiterminator by PTS-Mediated Phosphorylation

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Protein language-model embeddings for fast,accurate, and alignment-free protein structure prediction

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Poly(A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates

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ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins

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Structural characterization of human tryptophan hydroxylase 2 reveals that L-Phe is superior to L-Trp as the regulatory domain ligand

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Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal

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Mutational fitness landscape of human influenza H3N2 neuraminidase

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