Engineered miniature CRISPR-Cas system for mammalian genome regulation and editing

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A multiscale analysis of early flower development in Arabidopsis provides an integrated view of molecular regulation and growth control

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Rapid and robust optogenetic control of gene expression in Drosophila

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Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease

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Mutations from patients with IPEX ported to mice reveal different patterns of FoxP3 and Treg dysfunction

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SETDB1/NSD-dependent H3K9me3/H3K36me3 dual heterochromatin maintains gene expression profiles by bookmarking poised enhancers

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Several cell-intrinsic effectors drive type I interferon-mediated restriction of HIV-1 in primary CD4+ T cells

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High-resolution 3D spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae

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The Origin of Land Plants Is Rooted in Two Bursts of Genomic Novelty

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Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells

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Co-opted genes of algal origin protect C. elegans against cyanogenic toxins

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Inactivation of a wheat protein kinase gene confers broad-spectrum resistance to rust fungi

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Cooperative assembly confers regulatory specificity and long-term genetic circuit stability

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Random allelic expression in the adult human body

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Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones

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A natural gene drive system confers reproductive isolation in rice

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“Structure”-function relationships in eukaryotic transcription factors: The role of intrinsically disordered regions in gene regulation

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Endogenous transcripts direct microRNA degradation in Drosophila,and this targeted degradation is required for proper embryonic development

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Meiotic Cells Counteract Programmed Retrotransposon Activation via RNA-Binding Translational Repressor Assemblies

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Molecular Co-occupancy Identifies Transcription Factor Binding Cooperativity In Vivo

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