Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19

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S100A8/A9-alarmin promotes local myeloid-derived suppressor cell activation restricting severe autoimmune arthritis

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A conformational change in the N terminus of SLC38A9 signals mTORC1 activation

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Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition

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Structure Determination of the Transactivation Domain of p53 in Complex with S100A4 Using Annexin A2 as a Crystallization Chaperone

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A neural hub for holistic courtship displays

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A Synthetic Approach to Reconstruct the Evolutionary and Functional Innovations of the Plant Histone Variant H2A.W

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Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16

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Salicylic Acid Targets Protein Phosphatase 2A to Attenuate Growth in Plants

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Microglial Piezo1 senses Aβ fibril stiffness to restrict Alzheimer’s disease

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N6-methyladenosine (m6A) is an endogenous A3 adenosine receptor ligand

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Microglial A20 Protects the Brain from CD8 T-Cell-Mediated Immunopathology

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Crystal structure of the AlbEF complex involved in subtilosin A biosynthesis

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Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F

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A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells

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A cancer-associated METTL14 mutation induces aberrant m6A modification,affecting tumor growth

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SLC38A5 aggravates DC-mediated psoriasiform skin inflammation via potentiating lysosomal acidification

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Modulation of adenosine A2a receptor oligomerization by receptor activation and PIP2 interactions

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Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates

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The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis

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