Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway

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Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism

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KARATE: PKA-induced KRAS4B-RHOA-mTORC2 supercomplex phosphorylates AKT in insulin signaling and glucose homeostasis

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Shank3 Binds to and Stabilizes the Active Form of Rap1 and HRas GTPases via Its NTD-ANK Tandem with Distinct Mechanisms

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Amino acids-Rab1A-mTORC1 signaling controls whole-body glucose homeostasis

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Structural basis for the initiation of COPII vesicle biogenesis

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RHO GTPase of plants regulates polarized cell growth and cell division orientation during morphogenesis

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A Non-canonical BRCT-Phosphopeptide Recognition Mechanism Underlies RhoA Activation in Cytokinesis

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Membrane receptor-mediated mechano-transduction maintains cell integrity during pollen tube growth within the pistil

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Combined kinesin-1 and kinesin-3 activity drives axonal trafficking of TrkB receptors in Rab6 carriers

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The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression

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Nod factor receptor complex phosphorylates GmGEF2 to stimulate ROP signaling during nodulation

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Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis

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Coordinated Ras and Rac Activity Shapes Macropinocytic Cups and Enables Phagocytosis of Geometrically Diverse Bacteria

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RabX1 Organizes a Late Endosomal Compartment that Forms Tubular Connections to Lysosomes Consistent with a “Kiss and Run” Mechanism

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RhoJ Regulates α5β1 Integrin Trafficking to Control Fibronectin Remodeling during Angiogenesis

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Structural basis of mRNA binding by the human FERRY Rab5 effector complex

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A Plasma Membrane Nanodomain Ensures Signal Specificity during Osmotic Signaling in Plants

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An injury-responsive Rac-to-Rho GTPase switch drives activation of muscle stem cells through rapid cytoskeletal remodeling

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Live Imaging Reveals Listeria Hijacking of E-Cadherin Recycling as It Crosses the Intestinal Barrier

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