Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan

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Conformational Priming of RepA-WH1 for Functional Amyloid Conversion Detected by NMR Spectroscopy

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Regulation of hair cell and stomatal size by a hair cell-specific peroxidase in the grass Brachypodium distachyon

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ATP-site inhibitors induce unique conformations of the acute myeloid leukemia-associated Src-family kinase,Fgr

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The active DNA-PK holoenzyme occupies a tensed state in a staggered synaptic complex

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Co-adaptor driven assembly of a CUL3 E3 ligase complex

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Structural basis of SARM1 activation,substrate recognition,and inhibition by small molecules

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Dimerization of Cadherin-11 involves multi-site coupled unfolding and strand swapping

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Thermosensitive Nucleosome Editing Reveals the Role of DNA Sequence in Targeted Histone Variant Deposition

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A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination

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Conformational exchange divergence along the evolutionary pathway of eosinophil-associated ribonucleases

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Isotope tracing in adult zebrafish reveals alanine cycling between melanoma and liver

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Herbivore-driven disruption of arbuscular mycorrhizal carbon-for-nutrient exchange is ameliorated by neighboring plants

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Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting

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EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart

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Defining How Oncogenic and Developmental Mutations of PIK3R1 Alter the Regulation of Class IA Phosphoinositide 3-Kinases

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Uncovering cryptic pockets in the SARS-CoV-2 spike glycoprotein

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ATP-competitive and allosteric inhibitors induce differential conformational changes at the autoinhibitory interface of Akt1

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Rapid formation of new migration route and breeding area by Arctic geese

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(p)ppGpp controls stringent factors by exploiting antagonistic allosteric coupling between catalytic domains

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