Branched-chain keto acids inhibit mitochondrial pyruvate carrier and suppress gluconeogenesis in hepatocytes

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A microbial metabolite remodels the gut-liver axis following bariatric surgery

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FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption

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Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects

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Microbiota alterations in proline metabolism impact depression

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A bacterial bile acid metabolite modulates Treg activity through the nuclear hormone receptor NR4A1

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Flux regulation through glycolysis and respiration is balanced by inositol pyrophosphates in yeast

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Large neutral amino acid levels tune perinatal neuronal excitability and survival

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Intestinal hypoxia-inducible factor 2α regulates lactate levels to shape the gut microbiome and alter thermogenesis

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The probiotic L. casei Zhang slows the progression of acute and chronic kidney disease

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Dysbiosis-Induced Secondary Bile Acid Deficiency Promotes Intestinal Inflammation

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Diverse nitrogen signals activate convergent ROP2-TOR signaling in Arabidopsis

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Molecular and neuronal mechanisms for amino acid taste perception in the Drosophila labellum

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Apocryphal FADS2 activity promotes fatty acid diversification in cancer

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Ingested non-essential amino acids recruit brain orexin cells to suppress eating in mice

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PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport

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Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation

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Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1

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Activation of Oxidative Stress Response in Cancer Generates a Druggable Dependency on Exogenous Non-essential Amino Acids

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Amino acids-Rab1A-mTORC1 signaling controls whole-body glucose homeostasis

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