Architecture of a PKS-NRPS hybrid megaenzyme involved in the biosynthesis of the genotoxin colibactin

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A male-derived nonribosomal peptide pheromone controls female schistosome development

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Accurate de novo design of membrane-traversing macrocycles

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Lipid-mediated phase separation of AGO proteins on the ER controls nascent-peptide ubiquitination

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Innate Immunity Promotes Sleep through Epidermal Antimicrobial Peptides

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Computationally Designed Cyclic Peptides Derived from an Antibody Loop Increase Breadth of Binding for Influenza Variants

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Bombesin-like peptide recruits disinhibitory cortical circuits and enhances fear memories

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The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone

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DStabilize: A Web Resource to Generate Mirror Images of Biomolecules

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Oxytocin Influences Male Sexual Activity via Non-synaptic Axonal Release in the Spinal Cord

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Structural insights into the interplay of protein biogenesis factors with the 70S ribosome

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Inhibition of talin-induced integrin activation by a double-hit stapled peptide

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HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies

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Functional coupling of TRPM2 and extrasynaptic NMDARs exacerbates excitotoxicity in ischemic brain injury

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Structure and Function of the Bacterial Protein Toxin Phenomycin

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A nexus of intrinsic dynamics underlies translocase priming

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Boost immunizations with NA-derived peptide conjugates achieve induction of NA inhibition antibodies and heterologous influenza protections

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Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization

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Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism,microbiota, and T cell-induced inflammation

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Remodeling of Metastatic Vasculature Reduces Lung Colonization and Sensitizes Overt Metastases to Immunotherapy

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