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1.
Yunkai Lu Palgun Reddy Pulasani Reza Derakhshani Trent M. Guess 《Biomedical signal processing and control》2013,8(6):475-482
Traditional finite element (FE) analysis is computationally demanding. The computational time becomes prohibitively long when multiple loading and boundary conditions need to be considered such as in musculoskeletal movement simulations involving multiple joints and muscles. Presented in this study is an innovative approach that takes advantage of the computational efficiency of both the dynamic multibody (MB) method and neural network (NN) analysis. A NN model that captures the behavior of musculoskeletal tissue subjected to known loading situations is built, trained, and validated based on both MB and FE simulation data. It is found that nonlinear, dynamic NNs yield better predictions over their linear, static counterparts. The developed NN model is then capable of predicting stress values at regions of interest within the musculoskeletal system in only a fraction of the time required by FE simulation. 相似文献
2.
Vineeta Singh Mahvish Khan Saif Khan C. K. M. Tripathi 《Applied microbiology and biotechnology》2009,82(2):379-385
Artificial neural network (ANN) and genetic algorithm (GA) were applied to optimize the medium components for the production
of actinomycinV from a newly isolated strain of Streptomyces triostinicus which is not reported to produce this class of antibiotics. Experiments were conducted using the central composite design
(CCD), and the data generated was used to build an artificial neural network model. The concentrations of five medium components
(MgSO4, NaCl, glucose, soybean meal and CaCO3) served as inputs to the neural network model, and the antibiotic yield served as outputs of the model. Using the genetic
algorithm, the input space of the neural network model was optimized to find out the optimum values for maximum antibiotic
yield. Maximum antibiotic yield of 452.0 mg l−1 was obtained at the GA-optimized concentrations of medium components (MgSO4 3.657; NaCl 1.9012; glucose 8.836; soybean meal 20.1976 and CaCO3 13.0842 gl−1). The antibiotic yield obtained by the ANN/GA was 36.7% higher than the yield obtained with the response surface methodology
(RSM). 相似文献