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1.
Visual recognition of entire and partly masked geometric figure by men and women was studied. Probabilities of correct recognition of the entire (control) and partly masked figures (without some parts of their lines or corners) under conditions of their near-threshold tachistoscopic presentation were compared. A gradual decrease in recognition probability with increasing masking was observed. It was more pronounced for figures without some corners than for figures without part of their sides. Reliable gender differences were found: men better than women recognized figures, especially, with masked corners. Possible reasons for gender differences in recognition of geometrical figures are discussed, in particular, the role of striate sensitivity to a single light bar and a line crossing in the observed phenomena. 相似文献
2.
Shevelev IA Kamenkovich VM Sharaev GA 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》2000,50(3):403-409
Neurons tuned to line-crossings (corners, crosses, Y-like and three-ray star-like figures) of different shape and orientation rather than to a single bar were found in the area 17 of the cat visual cortex. We studied the relative role of lines and corners of 2D and 3D geometrical figures for their recognition by humans. Probability of figure recognition during its tachistoscopic presentation was compared for the whole (control) and partly masked figures. Sides or corners of the figures were masked to varying degrees and probabilities of correct response were compared. The recognition probability successively decreases with increasing extent of figure masking. This decrease is significantly more pronounced for the figures without corners than for the figures without part of the lines. The relatively greater significance of the corners than sides of geometrical figures for human visual recognition and some possible neuronal mechanisms of this effect are discussed. 相似文献
3.
Mikhaĭlova ES Slavutskaia AV Konyshev VA Shevelev IA Sharaev GA 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》2006,56(2):175-182
Temporal and amplitude characteristics of averaged visual evoked potentials to presentation of lines, corners and crosses with different orientation recorded in 19 adult healthy subjects were compared in 34 derivations. In all subjects, the latencies of P1, N2, and P3 were shorter while their amplitudes were higher for crosses than for lines. The effect of lengthening of P1 peak latency from occipital to temporal cortex was mostly pronounced for EPs to a bar, whereas as increase in the P1 amplitude was most evident for a cross-like figure. Correlation of these data with: i) greater magnitude and shorter latencies of responses to crosses vs. bars in a half of cat striate neurons, ii) sensitivity of cells in monkey inferior temporal cortex to star-like figures, and iii) relatively better human recognition of figures with comers than with lines, as well as significance of the effects obtained for detection of image features in different areas of the human visual cortex is discussed. 相似文献
4.
Recognition of shape of natural objects was studied during lateralized tachistoscopic presentation and different degree of noise-like ("rain drops") masking in 15 healthy subjects. Two sets of figures were used: halftone and contour ones. In all masking conditions, the mean group data showed a significantly better recognition of contour images by the left hemisphere as compared to the right hemisphere. The probability of correct response decreased with increase in the degree of masking. Contour figures were recognized significantly better than halftone figures. Gender differences in recognition were revealed. Male subjects displayed no hemispheric preference in recognition of both types of stimuli in both masking conditions. Possible neurophysiological mechanisms and functional significance of the findings are discussed. 相似文献
5.
Patricia A. Ramírez Andrea González Carezza Botto-Mahan 《Journal of Insect Behavior》2013,26(4):592-602
Masking, a type of camouflage, has been argued to function as an anti-predator mechanism helping to avoid detection or recognition by a prey or predator. However, research focused on the effects of masking on life history traits is scarce. We evaluated under laboratory conditions whether developmental time and survivorship in the absence of predators, and the probability to be predated by a potential predator are affected when the blood-feeding triatomine Mepraia spinolai masks with sand particles. Theoretically, it is expected to find a positive anti-predator effect of masking and the presence of trade-offs between development time and survival. We assigned M. spinolai nymphs to a masked or non-masked treatment and subjected them to a lizard, a potential predator. Results show masked nymphs reach the fifth instar faster and survive longer than non-masked nymphs, which is inconsistent with the trade-offs hypothesis we expected to find. In predation experiments, higher number of masked nymphs detected lizards before lizards detected them compared to non-masked nymphs. We suggest that masking may be an adaptation to the extreme climatic conditions the nymphs must face, and seems to render selective advantages to M. spinolai nymphs even in the absence of selective forces. 相似文献
6.
Kamenkovich VM Sharaev GA Shevelev IA 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》2007,57(2):155-160
Shape recognition of natural objects was studied under conditions of tachistoscopic (12 ms) presentation and different degree of noise-like ("rain drops") masking in 15 healthy subjects. Three set of figures were used: halftone, contour and silhouette. For all sets of figures, mean group data reveal a drop of the correct response probability with increase in masking. Recognition of contours was shown to be significantly better than that of halftone and silhouette figures, whereas halftone figures were recognized better than silhouettes. Possible neurophysiological mechanisms of the revealed phenomena and their functional implication are discussed. 相似文献
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Psychophysiological experiments were carried out to study the probability and latency of the recognition of significant and insignificant stimuli, namely, partially masked images of household items during their tachystoscopic presentation to subjects with normal vision. Data on a group of 16 subjects showed that the probability of recognition of significant stimuli was substantially higher as compared to the recognition of insignificant stimuli. The recognition latencies for significant stimuli were significantly higher as compared to insignificant stimuli. These effects were found using analysis of the distribution of the respective values and ANOVA. We did not find any gender effects. We suppose that these differences were related to a longer and more detailed recall and comparison of significant stimuli with other images of the set used, as well as to the effect of selective visual attention and interaction between the recognitions of significant and insignificant stimuli on the final result of identification of images. 相似文献
9.
Aleksandr Morgulis E Michael Gertz Alejandro A Sch?ffer Richa Agarwala 《Journal of computational biology》2006,13(5):1028-1040
The DUST module has been used within BLAST for many years to mask low-complexity sequences. In this paper, we present a new implementation of the DUST module that uses the same function to assign a complexity score to a sequence, but uses a different rule by which high-scoring sequences are masked. The new rule masks every nucleotide masked by the old rule and occasionally masks more. The new masking rule corrects two related deficiencies with the old rule. First, the new rule is symmetric with respect to reversing the sequence. Second, the new rule is not context sensitive; the decision to mask a subsequence does not depend on what sequences flank it. The new implementation is at least four times faster than the old on the human genome. We show that both the percentage of additional bases masked and the effect on MegaBLAST outputs are very small. 相似文献
10.
Optimization of immunohistochemical techniques to detect extracellular matrix proteins in fixed skin specimens 总被引:7,自引:0,他引:7
J M Folkvord D Viders A Coleman-Smith R A Clark 《The journal of histochemistry and cytochemistry》1989,37(1):105-113
Complete antigen visualization in the context of well-preserved tissue architecture is the goal of all immunohistochemical techniques. Frozen tissue section techniques achieve optimal antigen visualization but preserve tissue architecture poorly. On the other hand, formalin-fixed tissue section techniques preserve tissue architecture very well but result in antigen masking. Enzymatic digestion or salt extraction of formalin-fixed sections has been used to reestablish antigen expression. Recently acid-alcohol-fixed tissue has been used as a successful compromise between tissue architecture preservation and the visualization of cytoskeletal antigens. In an attempt to find an improved immunohistochemical process for non-cytoskeletal antigens, we compared avidin-biotin immunofluorescence staining in frozen, formalin-fixed, and acid-alcohol-fixed tissues. The fixed tissues were either untreated or treated with enzyme digestion or salt extraction. For this study, we examined healing cutaneous wounds in Yorkshire pigs with antibodies to fibronectin, laminin, von Willebrand factor VIII, and keratin. Although tissue architecture was poor, frozen sections provided the best antigen visualization and were therefore used as the standard for complete antigen expression. Formalin-fixed tissues had excellent tissue architecture, but most antigens were completely masked. Pre-treatment technique only partially overcame the antigen masking caused by formalin. In contrast, acid-alcohol fixation preserved tissue architecture almost as well as formalin and sometimes allowed complete antigen visualization; however, laminin and fibronectin were partially masked. Total recovery of the expression of these antigens could be obtained by pre-treating the acid-alcohol-fixed tissue with either hyaluronidase or 1 M NaCl. Therefore, acid-alcohol-fixed tissue appears best for extracellular matrix (ECM) protein immunostaining as well as for cytoskeletal staining. However, certain ECM antigens require hyaluronidase or 1 M NaCl treatment for optimal visualization. 相似文献
11.
Listening to speech in the presence of other sounds 总被引:1,自引:0,他引:1
Darwin CJ 《Philosophical transactions of the Royal Society of London. Series B, Biological sciences》2008,363(1493):1011-1021
Although most research on the perception of speech has been conducted with speech presented without any competing sounds, we almost always listen to speech against a background of other sounds which we are adept at ignoring. Nevertheless, such additional irrelevant sounds can cause severe problems for speech recognition algorithms and for the hard of hearing as well as posing a challenge to theories of speech perception. A variety of different problems are created by the presence of additional sound sources: detection of features that are partially masked, allocation of detected features to the appropriate sound sources and recognition of sounds on the basis of partial information. The separation of sounds is arousing substantial attention in psychoacoustics and in computer science. An effective solution to the problem of separating sounds would have important practical applications. 相似文献
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Cryostat sections of various substrates were treated with carbobenzoxychloride in acetone to modify antigens. By applying specific fluorescent antibodies, it could be shown that the antigenic determinants of rabbit gamma-globulin and bovine insulin were totally masked. The antigenicity of ACTH was markedly reduced, whereas the polysaccharide antigens of Salmonella typhimurium were only partially masked. After masking, antigenicity could be restored by treatment with nonspecific protease. The reversible protection of amino groups by carbobenzoxychloride may be a way to preserve protein antigens during embedding in plastics, as such materials also bind to amino groups, blocking the antigenicity of proteins. 相似文献
14.
Frith MC 《PloS one》2011,6(12):e28819
Detection of sequences that are homologous, i.e. descended from a common ancestor, is a fundamental task in computational biology. This task is confounded by low-complexity tracts (such as atatatatatat), which arise frequently and independently, causing strong similarities that are not homologies. There has been much research on identifying low-complexity tracts, but little research on how to treat them during homology search. We propose to find homologies by aligning sequences with "gentle" masking of low-complexity tracts. Gentle masking means that the match score involving a masked letter is min(0,S), where S is the unmasked score. Gentle masking slightly but noticeably improves the sensitivity of homology search (compared to "harsh" masking), without harming specificity. We show examples in three useful homology search problems: detection of NUMTs (nuclear copies of mitochondrial DNA), recruitment of metagenomic DNA reads to reference genomes, and pseudogene detection. Gentle masking is currently the best way to treat low-complexity tracts during homology search. 相似文献
15.
It is difficult to determine the reason why a patient complains of a bitter taste when their mouth is empty. We examined a new diagnostic test using a bitterness masking substance. The bitterness masking substance, 'Benecoat BMI-60' (hereafter BMI-60), is a masking substance specific to the taste cells' bitterness receptors. After patients gargled with BMI-60 solutions, the phantom sensation of bitterness was masked in some patients, but was not masked in others. Bitter substances in saliva seemed to be masked by BMI-60, but bitterness did not seem to be masked when the locus of the phantom sensation was within the peripheral nerve and/or the brain. The bitterness masking test is useful for diagnosis of the phantom sensation of bitter taste. 相似文献
16.
O O Iakimenko 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1975,25(1):101-109
A study was made of the mechanisms of discrimination of geometrical figures and their angles by fish and of the influence of repeated presentation of stimuli on recognition time. The experiment was made by the conditioning method with the use of two variants of food-procuring technique: simultaneous and successive choice of stimuli. It was shown that discrimination of geomentrical figures is achieved at the fist stage by the mechanism of selection, and after long training, by the mechanism of camparison with a chosen standard. The selection mechanism is also used for recognition of angles by their size. Certain combinations of angles differentiated not by size, but by orientation of their sides, are recognized by the mechanism of comparison with a standard. 相似文献
17.
K A Zaitseva V P Morozov A I Akopian 《Zhurnal evoliutsionno? biokhimii i fiziologii》1978,14(1):80-83
The paper presents data on the directional selectivity of hearing in the bottlenose dolphin as a function of masking noise angle. It has been shown that the hearing system of dolphins is characterised by sharp lowering of masked thresholds depending on the noise going in the high frequency region. The same effect is shown in man, but not so evidently. 相似文献
18.
Sevostyanova A Feklistov A Barinova N Heyduk E Bass I Klimasauskas S Heyduk T Kulbachinskiy A 《The Journal of biological chemistry》2007,282(30):22033-22039
Bacterial RNA polymerase holoenzyme relies on its sigma subunit for promoter recognition and opening. In the holoenzyme, regions 2 and 4 of the sigma subunit are positioned at an optimal distance to allow specific recognition of the -10 and -35 promoter elements, respectively. In free sigma, the promoter binding regions are positioned closer to each other and are masked for interactions with the promoter, with sigma region 1 playing a role in the masking. To analyze the DNA-binding properties of the free sigma, we selected single-stranded DNA aptamers that are specific to primary sigma subunits from several bacterial species, including Escherichia coli and Thermus aquaticus. The aptamers share a consensus motif, TGTAGAAT, that is similar to the extended -10 promoter. We demonstrate that recognition of this motif by sigma region 2 occurs without major structural rearrangements of sigma observed upon the holoenzyme formation and is not inhibited by sigma regions 1 and 4. Thus, the complex process of the -10 element recognition by RNA polymerase holoenzyme can be reduced to a simple system consisting of an isolated sigma subunit and a short aptamer oligonucleotide. 相似文献
19.
Natural ligands of the B cell adhesion molecule CD22 beta can be masked by 9-O-acetylation of sialic acids 总被引:4,自引:0,他引:4
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《The Journal of cell biology》1994,126(2):549-562
CD22 beta is a B cell-restricted phosphoprotein expressed on the surface of mature resting B cells. It mediates interactions with other cells partly or exclusively via recognition of alpha 2-6-linked sialic acids on glycoconjugates. The sialylated N-linked oligosaccharides recognized best by CD22 beta are common to many glycoproteins, suggesting that additional regulatory mechanisms may exist. Since the exocyclic side chain of sialic acid is required for recognition, we explored the effects of a naturally occurring modification of the side chain, 9-O-acetylation. Semisynthetic N-linked oligosaccharides terminating with 9-O-acetylated, alpha 2-6-linked sialic acids showed markedly reduced binding to CD22 beta relative to their non-O- acetylated counterparts. Murine lymphoid cells were probed for natural CD22 beta ligands that might be O-acetylated using recombinant soluble forms of CD22 beta (CD22 beta Rg) and influenza C esterase (CHE-Fc, which specifically removes 9-O-acetyl esters from sialic acids). By flow cytometry analysis, CD22 beta Rg binding to splenic B cells and a subset of T cells was increased by pretreatment with CHE-Fc, indicating that some potential CD22 beta ligands are naturally "masked" by 9-O- acetylation. Unmasking of these CD22 beta ligands by removal of 9-O- acetyl esters from intact splenocytes substantially increases their CD22 beta-dependent adhesion in an in vitro adhesion assay. Probing of murine lymphoid tissue sections by CD22 beta Rg and CHE-Fc treatment demonstrates regionally restricted and differentially expressed patterns of distribution between masked and unmasked ligands. For example, lymph node-associated follicular B cells express high levels of CD22 beta ligands, none of which are masked by 9-O-acetylation. In contrast, the ligands on lymph node-associated dendritic cells are almost completely masked by 9-O-acetylation, suggesting that masking may regulate interactions between CD22 beta-positive B cells and dendritic cells. In the thymus, only medullary cells express CD22 beta ligands, and a significant portion of these are masked by 9-O- acetylation, particularly at the cortical-medullary junction. Thus, 9-O- acetylation of sialic acids on immune cells is in a position to negatively regulate CD22 beta adhesion events in a manner depending on both cell type and tissue localization. 相似文献
20.
Presence of binding site for alpha-amylase and of masking protein for this site on mycelial cell wall of Aspergillus oryzae 总被引:3,自引:2,他引:1
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Mycelial cell wall of Aspergillus oryzae M-13 grown in an alpha-amylase-forming medium could not bind alpha-amylase (Taka-amylase A, EC 3.2.1.1). However, by treatment with 1.0 n NaOH at 100 C for 30 min, the wall gained the ability to bind alpha-amylase. This phenomenon was caused by removal of a factor (designated as masking factor) which masked the binding site for alpha-amylase. The masking factor was purified as a preparation giving a single peak in both ultracentrifugation (1.6S) and by gel electrophoresis (M(BPB), 1.0). Approximately 20 mug of the purified factor, bound to 10 mg of the alkali-treated mycelial cell wall, prevented the binding of approximately 100 mug of alpha-amylase or released approximately 100 mug of alpha-amylase which previously was bound to the alkali-treated wall. These findings indicate that the factor has much higher affinity than alpha-amylase for the binding site on the mycelial wall. The masking factor was inducibly formed accompanying the secretion of alpha-amylase. 相似文献