The Poetics of Purpose

Hackles have been raised in biosemiotic circles by T. L. Short’s assertion that semiosis, as defined by Peirce, entails “acting for purposes” and therefore is not found below the level of the organism (2007a:174–177). This paper examines Short’s teleology and theory of purposeful behavior and offers a remedy to the disagreement. Remediation becomes possible when the issue is reframed in the terms of the complexity sciences, which allows intentionality to be understood as the interplay between local and global aspects of a system within a system. What is called “acting for purposes” is not itself a type of behavior so much as a relationship between a dynamic system that “exists for a purpose” and its microprocesses that “serve purposes.” The “intentional object” of philosophy is recast here as the holistic self-organized dynamics of a system, which exists for the purpose of self-maintenance, and that constrains the parts’ behaviors, which serve the purpose of forming the system. (A “system” can be any emergent, e.g. an abiotic form, an adapted species, a self, a conditioned response, thought, or a set of ideas.) The self-organized whole, which is represented to the parts in their own constrained behaviors, assumes the guiding function so long attributed to the mysterious “intentional object.” If emergent self-causation is not disallowed, creative originality, as well as directionality, becomes part of the definition of purposeful behavior. Thus, key tools used here, required for understanding emergence, come from poetics rather than semoitics. In the microprocesses of self-organization, I find what I call “accidental” indices and icons — which are poetic in the sense that they involve mere metonymic contiguity and metaphoric similarity — and which are preferentially selected under constrained conditions allowing radically new connections to habituate into an “intentional” self-organized system that, not coincidentally, has some of the emergent characteristics of a conventional symbolic system.

The Law of the Lifegivers: The Domestication of Desire

The Law of the Lifegivers: The Domestication of Desire. René Devisch and Claude Brodeur. Langhorne, PA: Harwood Academic Publishers, 1999. 268 pp.     

Gravity Constraints Drive Biological Systems Toward Specific Organization Patterns

Different cell lineages growing in microgravity undergo a spontaneous transition leading to the emergence of two distinct phenotypes. By returning these populations in a normal gravitational field, the two phenotypes collapse, recovering their original configuration. In this review, we hypothesize that, once the gravitational constraint is removed, the system freely explores its phenotypic space, while, when in a gravitational field, cells are “constrained” to adopt only one favored configuration. We suggest that the genome allows for a wide range of “possibilities” but it is unable per se to choose among them: the emergence of a specific phenotype is enabled by physical constraints that drive the system toward a preferred solution. These findings may help in understanding how cells and tissues behave in both development and cancer.     

"The Horror": The Subject of Desire in Postcoioniai Studies

Imperial Leather: Race, Gender and Sexuality in the Colonial Contest. Anne McClintock. New York: Routledge, 1995. 449 pp.
Race and the Education of Desire: Foucault's History of Sexuality and the Colonial Order of Things. Ann Laura Stoler. Durham, NC: Duke University Press, 1995. 238 pp.
Colonial Desire: Hybridity in Theory, Culture, and Race. Robert J. C. Young. London: Routledge, 1995.236 pp.     

Toward Computational Cumulative Biology by Combining Models of Biological Datasets

A main challenge of data-driven sciences is how to make maximal use of the progressively expanding databases of experimental datasets in order to keep research cumulative. We introduce the idea of a modeling-based dataset retrieval engine designed for relating a researcher''s experimental dataset to earlier work in the field. The search is (i) data-driven to enable new findings, going beyond the state of the art of keyword searches in annotations, (ii) modeling-driven, to include both biological knowledge and insights learned from data, and (iii) scalable, as it is accomplished without building one unified grand model of all data. Assuming each dataset has been modeled beforehand, by the researchers or automatically by database managers, we apply a rapidly computable and optimizable combination model to decompose a new dataset into contributions from earlier relevant models. By using the data-driven decomposition, we identify a network of interrelated datasets from a large annotated human gene expression atlas. While tissue type and disease were major driving forces for determining relevant datasets, the found relationships were richer, and the model-based search was more accurate than the keyword search; moreover, it recovered biologically meaningful relationships that are not straightforwardly visible from annotations—for instance, between cells in different developmental stages such as thymocytes and T-cells. Data-driven links and citations matched to a large extent; the data-driven links even uncovered corrections to the publication data, as two of the most linked datasets were not highly cited and turned out to have wrong publication entries in the database.     

Toward Practical Biological Control of Parasitic Nematodes in Domestic Animals

In a series of laboratory and field experiments where the nematophagous fungus Arthrobotrys oligospora was mixed directly with feces it has been demonstrated that it is possible to use nematophagous fungi for biological control of animal parasitic nematodes. A procedure used for selection of nematophagous fungi that can pass the digestive tract of ruminants, horses, and pigs is described. The selected fungus, Duddingtonia flagrans, has been used in further field experiments, and the results have confirmed that by the addition of D. flagrans to feed supplement it is possible to reduce the parasitic burden significantly.     

Material Poetics of a Malay House

Material objects call to us and structure our being. They are not passive, while we are active—rather, they embroil us in their lives as much as we engage them. Hence, sociality is not solely a human function but necessarily involves environments and artefacts. The notion of material poetics is, in this sense, a mutually shaping matrix that affects social life and thought. This philosophy is explored through an encounter with a Malay house. The house is in many ways liminal—a place in which thought and image dwells. It is traditional, yet unique; it holds and expresses history, yet that history is elsewhere and legendary; is Malay but with Chinese decorations, which articulate hybridity; is specifically local, yet involved in national and international flows. It embraces both oscillation and direction. The house is made of wood. This paper takes up this element, showing how the wood not only shelters, but also leads us to venture out to a garden of trees and a dream of jungles where encounters with things, stories and myths subvert our normal categories and expectations. The house leads us places and clears things for us, leading us into a new social field.     

The Kinesin-1 Chemomechanical Cycle: Stepping Toward a Consensus

Kinesin-1 serves as a model for understanding fundamentals of motor protein mechanochemistry and for interpreting functional diversity across the kinesin superfamily. Despite sustained work over the last three decades, disagreements remain regarding the events that trigger the two key transitions in the stepping cycle: detachment of the trailing head from the microtubule and binding of the tethered head to the next tubulin binding site. This review describes the conflicting views of these events and highlights recent work that sheds light on these long-standing controversies. It concludes by presenting a consensus kinesin-1 chemomechanical that incorporates recent work, resolves discrepancies, and highlights key questions for future experimental work. It is hoped that this model provides a framework for understanding how diverse kinesins are tuned for their specific cellular roles.     

The Politics of Tradition: Toward a Generic Culture in Vanuatu

The paper examines the role of the elite in generating constructions of tradition in present-day Vanuatu. While stopping short of postulating a ‘conspiracy theory’ interpretation, the paper does argue that the proto-bureaucratic 'class' is attempting to gain control over a symbolic code derived from traditional practices (kastom) so as to promote social cohesion and establish a civil polity. The negative case of kava, a symbol of traditional culture which was significantly not included in this corpus is discussed at length.     

Beyond Anthropology: Toward a Man-Science

Culture and Biological Man: Explorations in Behavioral Anthropology. ELIOT D. CHAPPLE.
Ethology: The Biology of Behavior. IREN-ÄUS EIBL-EIBESFELDT. Erich Kling-hammer, trans.
Studies in Animal and Human Behaviour. Volume I. Volume II. KONRAD LORENZ. Robert Martin, trans.     

Scenting a Subject: Odour Poetics and the Politics of Space

Olfactory studies are truly multidisciplinary, from anthropology to zoology. What literary criticism can offer is analysis of the language of smell and the discourses of olfactory practice which give smell meanings. In this paper I explore the poetics of odour in selected contexts in the developed West of the twenty-first century. I argue that the language of smell is elusive, contradictory, disguised: nonetheless, it deploys metaphor, story, personal meaning and social meaning, all frames that ‘nest’ together. I demonstrate contradictions of olfactory practice with reference to urban space and technologies of scent, acting on bodies and places. I argue that a relationship between scent, identity and space can be understood in terms of an olfactory sublime, to which there is also resistance, sanctioned by new laws. In public space, the complexity of deodorisation appears in the conflict between fragrance-free and compulsory olfaction, as I argue with reference to Halifax, Nova Scotia and to the London Underground.