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1.
《Wetlands Ecology and Management》2002,10(1):97-101
Instructions for Authors
Wetlands Ecology and Management 相似文献2.
Editorial Notes and Announcements
Editorial Notes and Announcements 相似文献3.
Handling Editors and Reviewers
Handling Editors and Reviewers 相似文献4.
《Ichthyological Research》2010,57(2):214-214
Editorial Notes and Announcements
Editorial Notes and Announcements 相似文献5.
Dieter Czeschlik 《Planta》2011,233(5):857-858
In Recognition and Memoriam
In recognition and memoriam 相似文献6.
Paulo Cezar Rezende Fontes Marcelo Cleón de Castro Silva Glauco Vieira Miranda 《Biologia Plantarum》2001,44(4):3-8
Subject Index
Subject and Plant Index 相似文献7.
S. K. Sharma B. Sharma 《TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik》1986,71(6):820-825
Summary Seeds of two cultivars, each of macrosperma and microsperma varietal groups of lentil were mutagenised with gamma-rays and NMU to determine their mutagen sensitivity and mutability. The increasing doeses of gamma-rays and NMU decreased germination, root and shoot length, pollen fertility and plant survival, but increased the occurrence of leaf spots. The root system was found to be more sensitive to both mutagens than the shoot. The macrosperma varietal group was more sensitive to both the mutagens than microsperma group. In microsperma group, variety Pusa-1 was more sensitive to both the mutagens than L-259, while in the macrosperma group L-1491 showed more sensitivity to the mutagens than L-1492. Radio-sensitivity corresponded positively with chemosensitivity in both varietal groups. There was a positive relationship between radio- and chemo-sensitivity of the genotypes and their mutability. The results also revealed the existence of a parallelism between radiomutability and chemo-mutability. Due to saturation in the mutational events and vigour of both diplontic and haplontic selection in the biological material, the mutation frequency either decreased or remained constant at higher doses of the mutagens. 相似文献
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9.
Walter Kl?pffer Almut Beate Heinrich 《The International Journal of Life Cycle Assessment》2001,6(1):1-3
Editorial
Two planets and one journal 相似文献10.
Zhenhua Wang Dong Wang Liangliang Liu Dandan Guo Bacui Yu Bo Zhang Bo Han Xiling Sun Qiusheng Zheng 《Life sciences》2014
Aims
The purpose of this study is to evaluate the anti-metastatic effects of alteronol on melanoma B16F10 and B16F1 cells in vitro and in vivo.Main methods
Melanoma B16F1 and B16F10 cells were cultured in vitro. Cell proliferation was analyzed via 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay. The cell migration and invasion were evaluated via wound healing and transwell chamber assays. The activity of matrix metalloproteinase 2 (MMP-2) in culture supernatants was assessed via gelatin zymography. The expression of MMP-2 and TIMP-2 were detected via enzyme-linked immunosorbent assay (ELISA) assay. The anti-metastatic ability in vivo was detected through experimental lung metastasis.Key findings
The data indicate that alteronol can inhibit the proliferation, invasion, and migration of B16F1 and B16F10 cells in vitro and in vivo, decrease the activity and expression of MMP-2, enhance the expression level of Tissue Inhibitor of Metalloproteinase-2 (TIMP-2), and inhibit the experimental lung metastasis of B16F1 and B16F10 cells.Significance
Although alteronol and taxol are obtained from the same source, these substances do not destroy the rare resource; the mechanisms of them on tumor growth inhibition are different. Conversely, alteronol treatment had lesser effects on normal cells revealing for a selective property and a strong competitive advantage. 相似文献11.
Agrobacterium and plant genetic engineering 总被引:27,自引:0,他引:27
Erratum
Agrobacterium and plant genetic engineering 相似文献12.
Historical Biographies
Lofarma allergeni and allergies 相似文献13.
14.
Editorial
Microbiology and biotechnology education in India 相似文献15.
Background
This study aims to introduce the diagnosis and surgical treatment of the rare disease multiple endocrine neoplasia type 2A (MEN 2A).Methods
Thirteen cases of MEN 2A were diagnosed as medullary thyroid carcinoma (MTC) and pheochromocytoma by biochemical tests and imaging examination. They were treated by bilateral adrenal tumor excision or laparoscopic surgery.Results
Nine patients were treated by bilateral adrenal tumor excision and the remaining four were treated by laparoscopic surgery for pheochromocytoma. Ten patients were treated by total thyroidectomy and bilateral lymph nodes dissection and the remaining three were treated by unilateral thyroidectomy for MTC. Up to now, three patients have died of MTC distant metastasis.Conclusions
We confirmed that MEN 2A can be diagnosed by biochemical tests and imaging examination when genetic testing is not available. Surgical excision is the predominant way to treat MEN 2A; pheochromocytoma should be excised at first when pheochromocytoma and MTC occur simultaneously. 相似文献16.
Editorial Notes and Announcements
Editorial Notes and Announcements 相似文献17.
《Wetlands Ecology and Management》2001,9(1):75-79
Instructions for Authors
Wetlands Ecology and Management 相似文献18.
Kumiko Sakai-Kato Masayuki Hidaka Keita Un Toru Kawanishi Haruhiro Okuda 《Biochimica et Biophysica Acta (BBA)/General Subjects》2014
Background
Amorphous silica particles with the primary dimensions of a few tens of nm, have been widely applied as additives in various fields including medicine and food. Especially, they have been widely applied in powders for making tablets and to coat tablets. However, their behavior and biological effects in the gastrointestinal tracts associated with oral administration remains unknown.Methods
Amorphous silica particles with diameters of 50, 100, and 200 nm were incubated in the fasted-state and fed-state simulated gastric and intestinal fluids. The sizes, intracellular transport into Caco-2 cells (model cells for intestinal absorption), the Caco-2 monolayer membrane permeability, and the cytotoxicity against Caco-2 cells were then evaluated for the silica particles.Results
Silica particles agglomerated in fed-state simultaneous intestinal fluids. The agglomeration and increased particles size inhibited the particles' absorption into the Caco-2 cells or particles' transport through the Caco-2 cells. The in vitro cytotoxicity of silica particles was not observed when the average size was larger than 100 nm, independent of the fluid and the concentration.Conclusion
Our study indicated the effect of diet on the agglomeration of silica particles. The sizes of silica particles affected the particles' absorption into or transport through the Caco-2 cells, and cytotoxicity in vitro, depending on the various biological fluids.General significance
The findings obtained from our study may offer valuable information to evaluate the behavior of silica particles in the gastrointestinal tracts or safety of medicines or foods containing these materials as additives. 相似文献19.
20.
《Ichthyological Research》2011,58(2):193-193