共查询到19条相似文献,搜索用时 93 毫秒
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《昆虫学报》2017,(5)
同源异形盒基因(homeobox genes)是一类具有180 bp保守序列的基因,在生物发育的调控中起着重要作用。昆虫幼虫的腹足在位置和数目上均表现出丰富的多样性,使其成为进化发育生物学研究的主要对象之一。通过对昆虫幼虫腹足发育过程中相关同源异形盒基因的研究,既可了解腹足的发育机制,又可加深对同源异形盒基因进化和功能的理解。本文简要介绍同源异形盒基因的概况,重点总结了同源异形盒基因在昆虫幼虫腹足发育方面的研究进展,包括通过相关同源异形盒基因时空表达模式来揭示腹足的附肢起源、腹足发育的调控通路中相关同源异形盒基因的功能和进化等,尤其是腹部Hox家族基因对Distal-less基因的抑制作用及其在不同昆虫类群中的进化,以及该领域目前存在的主要争议,期望为相关研究提供参考。 相似文献
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基于模式植物拟南芥(Arabidopsis thaliana)和金鱼草(Antirrhinum majus)花器官突变体研究提出的四聚体模型揭示了花同源异型蛋白的相互作用方式;进一步提出的核小体拟态模型,解释了花同源蛋白四聚体调控目标靶基因的分子机理。被子植物花器官形态多样化与MADS-box基因的表达模式和功能分化密切相关。多年生被子植物花发育的高通量转录组分析表明,多种基因参与调控花器官发育过程。本文重点综述了被子植物花器官发育的模型演变、MADS-box基因结构和基因重复、miRNA调控以及相关转录组分析的最新研究成果,并对花器官发育的研究前景进行了展望。 相似文献
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最近,美国哈佛药学院的Ford发现同源异形盒(homeobox)基因在细胞周期、发育以及癌症发展中起着重要的链接作用[1]同源异形盒基因是与细胞正常分化、发育相关的转录因子,最初作为果蝇同源异形突变中的重要座位而得名。此后,陆续有170多个同源异形盒基因在各类物种中被发现。同源异形盒基因的共同点是具有183个核苷酸长度的同源区,编码61个氨基酸。同源异形盒基因同源区表达蛋白通过其DNA结合活性及其下游基因转录活性发挥作用。Lawrence等[2]推测哺乳动物同源异形盒表达蛋白的作用目标为编码细胞外层蛋白质的基因,粘… 相似文献
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花同源异型MADS-box 基因在被子植物中的功能保守性和多样性 总被引:1,自引:0,他引:1
MADS-box基因家族成员作为转录调控因子在被子植物花发育调控中发挥关键作用。本文以模式植物拟南芥(Arabidopsis thaliana) 和水稻 (Oryza sativa)为例, 综述了近10年来对被子植物(又称有花植物)两大主要类群——核心真
双子叶植物和单子叶植物花同源异型MADS-box基因的研究成果, 分析MADS-box基因在被子植物中的功能保守性和多样性,同时探讨双子叶植物花发育的ABCDE模型在多大程度上适用于单子叶植物。 相似文献
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花同源异型MADS-box基因在被子植物中的功能保守性和多样性 总被引:6,自引:2,他引:4
MADS-box基因家族成员作为转录调控因子在被子植物花发育调控中发挥关键作用。本文以模式植物拟南芥(Arabidopsis thaliana)和水稻(Oryza sativa)为例,综述了近10年来对被子植物(又称有花植物)两大主要类群——核心真双子叶植物和单子叶植物花同源异型MADS-box基因的研究成果,分析MADS-box基因在被子植物中的功能保守性和多样性,同时探讨双子叶植物花发育的ABCDE模型在多大程度上适用于单子叶植物。 相似文献
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同源异形盒(homeobox)基因是最先在果蝇中发现的一段长约180碱基对的DNA片段,这些基因影响果蝇的早期发育,并能编码出高度保守的DNA结合区域。近来,在一些脊椎动物中亦分离到同源异形盒基因,这些基因在脊椎动物中的胚胎期表达形式类似于果蝇。因此,一些脊椎动物同源异形盒基因可能控制早期发育,并且可能在成年分化过程中起重要作用。T、B淋巴细胞等血液细胞是从造血干细胞分化来的。实验结果表明,同源异形盒基因可能参与造血细胞分化的控制。 相似文献
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MADS-box基因在植物发育中的功能 总被引:11,自引:0,他引:11
MADS-box基因是一类序列特异的调节基因家族,是同源异型基因。它编码的蛋白质是一类转录因子,在植物的发育尤其在花器官的发育调控中起作用。文章介绍MADS-box基因调控植物开花的作用模式、MADS-box基因间的相互调控以及MADS-box基因功能的研究进展。 相似文献
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Ezhova TA 《Genetika》1999,35(11):1522-1537
A vast amount of information on the genetic control of plant development has been obtained in Arabidopsis thaliana with classical genetic and molecular biological methods. The genes involved in multistep regulation of floral morphogenesis have been identified. The formation of floral meristem is controlled by the LEAFY (LFY), UNUSUAL FLORAL ORGANS (UFO), APETALA1 (AP1), and APETALA2 (AP2) genes. Studies of the abruptus and bractea recessive monogenic mutants from the collection of the Department of Genetics and Selection, Moscow State University, showed that the ABRUPTUS (ABR) and BRACTEA (BRA) genes also play an important role in inflorescence differentiation. The ABR gene controls the early formation of organ primordia on the inflorescence and the formation of floral organ primordia after floral initiation. Further differentiation of inflorescence organ primordia in vegetative or generative organs depends on the activity of the LFY gene, and floral organ identity is determined by the homeotic genes. Presumably, the major function of the ABR gene is to determine the auxin polar transport. The BRA gene suppresses the development of bracts on the inflorescence and constrains cell division at the base of primordia of rosette and cauline leaves. 相似文献
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Conservation and diversity in flower land 总被引:1,自引:0,他引:1
During the past decade, enormous progress has been made in understanding the molecular regulation of flower development. In particular, homeotic genes that determine the identity of the floral organs have been characterised from different flowering plants, revealing considerable conservation among angiosperm species. On the other hand, evolutionary diversification has led to enormous variation in flower morphology. Increasing numbers of reports have described differences in the regulation, redundancy and function of homeotic genes from various species. These fundamentals of floral organ specification are therefore an ideal subject for comparative analyses of flower development, which will lead to a better understanding of plant evolution, plant development and the complexity of molecular mechanisms that control flower development and morphology. 相似文献
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Himeno M Neriya Y Minato N Miura C Sugawara K Ishii Y Yamaji Y Kakizawa S Oshima K Namba S 《The Plant journal : for cell and molecular biology》2011,67(6):971-979
Abnormal flowers are often induced by infection of certain plant pathogens, e.g. phytoplasma, but the molecular mechanisms underlying these malformations have remained poorly understood. Here, we show that infection with OY-W phytoplasma (Candidatus Phytoplasma asteris, onion yellows phytoplasma strain, line OY-W) affects the expression of the floral homeotic genes of petunia plants in an organ-specific manner. Upon infection with OY-W phytoplasma, floral morphological changes, including conversion to leaf-like structures, were observed in sepals, petals and pistils, but not in stamens. As the expression levels of homeotic genes differ greatly between floral organs, we examined the expression levels of homeotic genes in each floral organ infected by OY-W phytoplasma, compared with healthy plants. The expression levels of several homeotic genes required for organ development, such as PFG, PhGLO1 and FBP7, were significantly downregulated by the phytoplasma infection in floral organs, except the stamens, suggesting that the unique morphological changes caused by the phytoplasma infection might result from the significant decrease in expression of some crucial homeotic genes. Moreover, the expression levels of TER, ALF and DOT genes, which are known to participate in floral meristem identity, were significantly downregulated in the phytoplasma-infected petunia meristems, implying that phytoplasma would affect an upstream signaling pathway of floral meristem identity. Our results suggest that phytoplasma infection may have complex effects on floral development, resulting in the unique phenotypes that were clearly distinct from the mutant flower phenotypes produced by the knock-out or the overexpression of certain homeotic genes. 相似文献
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The blooming of grass flower development 总被引:11,自引:0,他引:11
The past half decade has provided a wealth of information concerning the molecular and genetic control of floral organ and meristem identity in dicotyledonous plants. Comparatively little is understood about these processes in grass species in spite of the importance that these species play in human agriculture. The isolation of grass genes that are homologous to dicot floral homeotic genes in combination with recent advances in reverse genetic technology and improvements in cereal transformation opens the door for understanding molecular mechanisms of grass flower development. Such information will also focus attention on the evolutionary relationships between grass and dicot flowers and the degree to which the developmental pathways leading to reproductive organ development in divergent angiosperms have utilized conserved mechanisms. 相似文献
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Negative regulation of the Arabidopsis homeotic gene AGAMOUS by the APETALA2 product. 总被引:65,自引:0,他引:65
We characterized the distribution of AGAMOUS (AG) RNA during early flower development in Arabidopsis. Mutations in this homeotic gene cause the transformation of stamens to petals in floral whorl 3 and of carpels to another ag flower in floral whorl 4. We found that AG RNA is present in the stamen and carpel primordia but is undetectable in sepal and petal primordia throughout early wild-type flower development, consistent with the mutant phenotype. We also analyzed the distribution of AG RNA in apetela2 (ap2) mutant flowers. AP2 is a floral homeotic gene that is necessary for the normal development of sepals and petals in floral whorls 1 and 2. In ap2 mutant flowers, AG RNA is present in the organ primordia of all floral whorls. These observations show that the expression patterns of the Arabidopsis floral homeotic genes are in part established by regulatory interactions between these genes. 相似文献
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目的:探讨草原龙胆花发育的分子机制,为进一步阐述花器官同源异型、属于MADS-box基因家族的一系列基因在调节开花植物花瓣和雄蕊的发育中的作用奠定基础。方法:以草原龙胆不同发育时期的花器官(萼片、花瓣、雄蕊、雌蕊)原基的cDNA作为试验方(tester),以茎叶组织的cDNA作为驱动方(driver),利用抑制性消减杂交技术构建了一个富集花器官发育特性基因的抑制性差减cDNA文库。对抑制性差减cDNA文库进行筛选、测序及Blast同源性比较。结果:获得了与花器官发育相关的特异性基因。结论:构建了抑制性差减cDNA文库,为克隆草原龙胆花器官发育特异性基因全长序列奠定了基础。 相似文献