Cancer et Hérédité

Sans résumé     

Radiopharmaceutiques et réglementations

The radiopharmaceuticals are products that combine two very stringent regulatory requirements from two different authorities: as medicine from a pharmaceutical point of view (Afssaps) and as radioactive source with specific authorization (ASN). This article discusses the different regulatory constraints imposed by these authorities but suggests also that legislation is supposed to be modified in the coming years in collaboration with nuclear physicians and their Society (SFMN).     

Fonction sexuelle et bilan sexologique de i’homme paraplégique et tétraplégique

This paper describes the sexological examination of spinal cord injured men. The complete exam includes a clinical interview, neurological examination, an EMG of the pelvic floor, a urodynamic examination and ano-rectal exploration, and the objective recording of the man’s sexual response to reflex and psychogenic professionals or psychologists and sextherapists can proceed with a more thorough interview which evaluates number of the elements of the physical examination. The results of the investigation give rise to a number of clinical entities described in terms of lesion levels with respect to the innervation of the reproductive system. Lesions can therefore be classified as being located above the two pathways of erection, or extended to the cauda equina. Each lesion type is associated with a given pronostic of erectile and ejaculatory function. The accompanying physiological recording of penile responses further helps to establish a differential diagnosis between an exclusively organic dysfunction or a primarily psychogenic dysfunction in spinal cord injured men.     

Psammocarcinome ovarien et médecine nucléaire

We report three cases of ovarian psammocarcinoma, which is a serous adenocarcinoma having psammoma calcifications. The FDG uptake in the psammomatous lesions is due to the tissular part of the lesion and the technetium-99m labelled agents uptake to its calcified part. Calcifications are detected on CT scans. Therefore, they are relatively simple to diagnose by nuclear medicine which is useful given relatively the better prognosis of the psammomatous ovarian serous carcinoma when compared to the serous one.     

Spermatogénèse et Paraplégie

In this article, the paraplegics’ possibilities for procreation will be examined. A first chapter will deal with the testicle functioning along with the study of hormonal measuring and testicle histology (study involving 100 patients). As a result, it appears that, after a testicle biopsy, there is a testicle lesion of neurological origin that is sometimes irreversible. On the contrary, the endocrinal testicle lesions have proved reversible under stimulation or spontaneously. A second chapter will deal with the different techniques to obtain an ejaculation and the semen analysis. The techniques that were used being: massage by vibrator, electroejaculation, ejaculation through pharmacological stimulation. The study focuses on 124 ejaculatory tests among which 64 forward ejaculations (52%) and 4 bachward ejaculations (3%) were obtained. The resulting semen analysis revealed a spermatozoon count greater than 20 millions per millilitre (that is 51,5%) and smaller than 5 millions in 11 cases (16%).     

Chromosomes et hétérochromosomes de ténébrionidés

Sans résumé Avec 81 figures dans le texte     

Mode d'action et propriétés des facteurs inducteurs issus du mésenchyme gastrique et des mésenchymes hétérologues

Résumé Des expériences d'associations d'épithélium gastrique de foetus de Lapin et de mésenchyme homologue ou hétérologue, partielles ou par membrane filtrante interposée, mettent en évidence l'existence de deux types de facteurs inducteurs.Le premier facteur induit la morphogenèse de l'épithélium. Il est thermostable et hautement diffusible.Le deuxième facteur, organospécifique, est plus ou moins favorable à la différenciation de l'épithélium gastrique suivant la nature du mésenchyme. Faiblement diffusible et thermolabile, il est élaboré dans la phase cytoplasmique des cellules mésenchymateuses.

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Action and properties of inductive factors proceeding from gastric and heterologous mesenchymes

Summary Experimental associations of gastric epithelium of the Rabbit foetus with homologous or heterologous mesenchyme, separated by membrane filter or partially associated, permit us to prove the existence of two types of inductors.The first factor induces the epithelial morphogenesis. It is thermostable and highly diffusible.The second factor, organospecific, is more or less favorable to the differentiation of the gastric epithelium according to the nature of the mesenchyme. Lightly diffusible and thermolabile, it is elaborated in the cytoplasmic phase of the mesenchymal cells.