Two escape routes from the paradigm of monistic authenticity: post-imperialist and federal perspectives on plural and complex identities

Despite a recent explosion of works emphasizing the increasingly plural and complex character of identity, political and social elites' interpretations of identities have continued to be dominated by the paradigm of monistic authenticity. In the face of this resilience, theorists must say more about the formation, meaning and implications of plural and complex identities. They must provide social and political actors with a credible alternative language to make sense of the actual or potential plurality of their allegiances. This article aims at contributing to the task by relying on the complementary merits of two traditions that used to ignore each other: post-imperialism and federalism. First, we suggest that post-imperialism may provide a language for redefining communities and individual-community relationships in a pluralist way. Second, we argue that the language of federalism has a high – and neglected – potential to answer the political and normative questions raised by post-imperialism.     

Best practices for authenticating cell lines

Experiments using cell cultures are only valid to the extent that the cell culture is a true model system for the biological system being investigated. To assure that a cell line is and remains an appropriate biological model, its identity, purity, ploidy, and phenotype must be maintained. These characteristics comprise and determine the authenticity of a cell line. Routine monitoring of the cell line through microscopic examination of morphology can help to determine authenticity, as can the determination of phenotypic status. Assays designed to confirm cell identity and ploidy and freedom from cross-contaminating cell types may need to be performed at certain times, as such information may not be obtained through morphologic and phenotypic examinations alone. The best practices associated with establishing cell line authenticity are described in this article.     

On the Origin of Language

Thomas Sebeok and Noam Chomsky are the acknowledged founding fathers of two research fields which are known respectively as Biosemiotics and Biolinguistics and which have been developed in parallel during the past 50 years. Both fields claim that language has biological roots and must be studied as a natural phenomenon, thus bringing to an end the old divide between nature and culture. In addition to this common goal, there are many other important similarities between them. Their definitions of language, for example, have much in common, despite the use of different terminologies. They both regard language as a faculty, or a modelling system, that appeared rapidly in the history of life and probably evolved as an exaptation from previous animal systems. Both accept that the fundamental characteristic of language is recursion, the ability to generate an unlimited number of structures from a finite set of elements (the property of ‘discrete infinity’). Both accept that human beings are born with a predisposition to acquire language in a few years and without apparent efforts (the innate component of language). In addition to similarities, however, there are also substantial differences between the two fields, and it is an historical fact that Sebeok and Chomsky made no attempt at resolving them. Biosemiotics and Biolinguistics have become two separate disciplines, and yet in the case of language they are studying the same phenomenon, so it should be possible to bring them together. Here it is shown that this is indeed the case. A convergence of the two fields does require a few basic readjustments in each of them, but leads to a unified framework that keeps the best of both disciplines and is in agreement with the experimental evidence. What is particularly important is that such a framework suggests immediately a new approach to the origin of language. More precisely, it suggests that the brain wiring processes that take place in all phases of human ontogenesis (embryonic, foetal, infant and child development) are based on organic codes, and it is the step-by-step appearance of these brain-wiring codes, in a condition that is referred to as cerebra bifida, that holds the key to the origin of language.     

Mongolian Ethnicity and Linguistic Anxiety in China

Language is one of the official criteria of defining a nationality in socialist China, but it simultaneously has been subjected to an "ideology of contempt" by the Chinese regime that builds nationality only to destroy it. This article examines the linguistic anxiety displayed by the Mongols and their controversial language revitalization efforts in a social environment in which they have become an absolute minority even while they have formal autonomy under their name. The tremendous cost—both emotional and economic—at which such language maintenance comes suggests that nationality in China may not be understood as primarily cultural but, instead, as political. As more Mongols lose their language, arguably the last bastion of their "nationality" status, they face the prospect of becoming a deinstitutionalized, depoliticized, and deterritorialized "ethnic group" in a racialized "Chinese Nation." [Keywords: language, nationality, ethnic group, Mongols, Chinese National Multiculturalism]     

After Authenticity at an American Heritage Site

This essay explores what happens to a heritage site "after authenticity." The site is Colonial Williamsburg, one of the most ambitious reconstruction projects ever undertaken and a place intended to be experienced as an objective correlate of an American national "identity." Because it makes such claims, throughout its history the site has been subject to critiques by those wishing to undermine its authority to speak as the voice of an all-encompassing America. Moreover, in the past 20 years, professional historians at Colonial Williamsburg have become articulate on-site critics of the epistemology of authenticity as they promulgate a historiography currently popular in history museums and in the academy.     

The Authentic (In)Authentic: Bushman Anthro‐Tourism

Focusing on tourism ventures that market contact with so‐called bushmen, this paper examines some of the current dynamics and consequences of cultural tourism in Namibia, where the Government has instituted a series of progressive policies to promote local control over tourism development. While notions of primitive cultural otherness continue to feature centrally in tourist demand for contact with “bushmen,” the community‐based and collaborative tourism’ ventures currently being developed in Namibia teach tourists to see their “bushman” hosts as modernizing producers of tourism in their own right, and not just as objects of touristic commodification. Drawing from the anthropological literature on tourism and authenticity, and on the work of Slavoj Zizek on the workings of modern ideology, we argue that such ventures encourage tourists to practise a sort of “meta‐tourism,” in which the authenticity of “traditional bushmen” is replaced by the meta‐authenticity of a tourism experience that thematizes its own effects on the lives of those being visited. For the “bushman” participants in such ventures, we contend, the financial and political benefits of tourism, substantial as they can sometimes be, are ultimately offset by the developmentalist underpinnings of meta‐tourist discourse, which casts “bushmen” as forever not‐quite‐yet fully modern, in perpetual contrast to the tourists who visit them.     

The molecular features of chromosome pairing at meiosis: the polyploid challenge using wheat as a reference

During meiosis, chromosome numbers are halved, leading to haploid gametes, a process that is crucial for the maintenance of a stable genome through successive generations. The process for the accurate segregation of the homologues starts in pre-meiosis as each homologue is replicated and the respective products are held together as two sister chromatids via specific cohesion proteins. At the start of meiosis, each chromosome must recognise its homologue from amongst all the chromosomes present in the nucleus and then associate or pair with that homologue. This process of homologue recognition in meiosis is more complicated in polyploids because of the greater number of related chromosomes. Despite the presence of these related chromosomes, for polyploids such as wheat to produce viable gametes, they must behave as diploids during meiosis with only true homologues pairing. In this review, the relationship between the Ph1 cyclin-dependent kinase (CDK)-like genes in wheat and the CDK2 genes in mammals and their involvement in controlling this process at meiosis is examined.     

Structural and functional relationship between the Ph1 locus protein 5B2 in wheat and CDK2 in mammals

During meiosis, chromosome numbers are halved, leading to haploid gametes, a process that is crucial for the maintenance of a stable genome through successive generations. The process for the accurate segregation of the homologues starts in pre-meiosis as each homologue is replicated and the respective products are held together as two sister chromatids via specific cohesion proteins. At the start of meiosis, each chromosome must recognise its homologue from amongst all the chromosomes present in the nucleus and then associate or pair with that homologue. This process of homologue recognition in meiosis is more complicated in polyploids because of the greater number of related chromosomes. Despite the presence of these related chromosomes, for polyploids such as wheat to produce viable gametes, they must behave as diploids during meiosis with only true homologues pairing. In this review, the relationship between the Ph1 cyclin-dependent kinase (CDK)-like genes in wheat and the CDK2 genes in mammals and their involvement in controlling this process at meiosis is examined.     

Product and contaminant measurement in bioprocess development by SELDI‐MS

Bioprocesses for therapeutic protein production typically require significant resources to be invested in their development. Underlying these efforts are analytical methods, which must be fit for the purpose of monitoring product and contaminants in the process. It is highly desirable, especially in early‐phase development when material and established analytical methods are limiting, to be able to determine what happens to the product and impurities at each process step with small sample volumes in a rapid and readily performed manner. This study evaluates the utility of surface‐enhanced laser desorption ionization mass spectroscopy (SELDI‐MS), known for its rapid analysis and minimal sample volumes, as an analytical process development tool. In‐process samples from an E. coli process for apolipoprotein A‐IM (ApoA‐IM) manufacture were used along with traditional analytical methods such as HPLC to check the SELDI‐MS results. ApoA‐IM is a naturally occurring variant of ApoA‐I that appears to confer protection against cardiovascular disease to those that carry the mutated gene. The results show that, unlike many other analytical methods, SELDI‐MS can handle early process samples that contain complex mixtures of biological molecules with limited sample pretreatment and thereby provide meaningful process‐relevant information. At present, this technique seems most suited to early‐phase development particularly when methods for traditional analytical approaches are still being established. © 2009 American Institute of Chemical Engineers Biotechnol. Prog., 2010     

MEDICAL PLANNING FOR DISASTER—Brief Résumé of Accomplishments in California 1950-1959

Extensive accumulation and dispersal of medical supplies and equipment has been carried out in this state since 1950. Although such medical supplies and equipment are inadequate for an all out war type disaster their addition to the medical disaster preparedness program represents a great contribution and efforts must be made to continually supplement them.All hospitals must have a disaster plan which is well understood and which must be tested by actual test exercises at least once each year.Preparations for major disasters of all types are costly and time-consuming but represent one of the best possible investments which we can make as insurance against the loss of thousands of casualties.It is the responsibility of each physician to prepare himself and his family in anticipation of being exposed to natural or man-made disasters.     

Zombie Linguistics: Experts,Endangered Languages and the Curse of Undead Voices

The alarming projection that up to ninety per cent of the world's languages will become extinct by the end of this century has prompted a new sense of urgency among linguists and other language scholars to rush out and record the last utterances from the last speakers of ‘endangered languages’. As the last speaker utters her/his last words, the ‘expert’ is there to record this important moment and preserve it for all time. Among the benefits from such preservation efforts is the ability to play back the recordings at any time in any place. In popular media this process is described as ‘saving the language’ through recording and documentation. Unfortunately, these recordings are not living voices. Rather, they are zombie voices—undead voices that are disembodied and techno-mechanized. They are cursed with being neither dead nor alive. They become artefacts of technological interventions, as well as expert valorisations of linguistic codes. Expert rhetoric compounds the problem by the use of metaphoric frames such as death, endangerment and extinction. Metaphors not only frame discourses of language endangerment, but they also frame and influence actions and interventions. This essay critically evaluates the metaphors used by language experts to understand the unintended consequences for community members who are actively revitalising and reclaiming their languages. The essay also identifies key strategies used by community language activists to ignore existing metaphors, while creating new metaphors to potentiate new solutions to language death to promote emergent vitalities.     

The Role of Language in Nation-Building within the European Union

Europe is home to a vast array of indigenous languages, not to mention numerous immigrant languages. European Union (EU) acknowledgement of “national” languages as official languages results in a privileged status for these languages vis-à-vis the minority languages with which they cohabit. This support prevents hegemony by a single language such as English, yet the EU simultaneously undermines these national languages domestically by promoting their minority language competitors. This paradox can only be understood by examining the developing model for European identity whereby identity is viewed as variable and multi-faceted, rooted in multilingual facility and the absence of a single, monolithic source of identity. If the project of creating a European identity is viewed as nation-building,it is central to consider how the issue of language diversity is addressed at the European level. The paper begins by discussing the concept of national identity and the central role that language plays in its determination, as well as what modern conceptions of language planning bring to this process. After exploring the European language terrain, the paper considers whether the EU can even be said to have a language policy. The discussion focuses on multilingual education programs, the treatment of minority languages, and the issue of languages spoken by immigrant populations. Having presented these conceptual tools and policy surveys, an analytical framework is introduced that situates the nation-building process in relation to the creation of a common European identity.     

Conducting Research with Human Subjects in International Settings: Ethical Considerations

Biomedical research in international settings is undergoing expansive growth and may potentially result in far-reaching benefits, such as direction of research resources toward solving basic health care needs of world populations. However, key ethical concerns surround this expansion and must be carefully considered by international researchers. International research is impacted by differences in language, culture, regulatory structures, financial resources, and possibly ethical standards. Local community leadership involvement in the planning stages of research is imperative. Especially in resource-poor countries, the research agenda must be designed to address local needs and provide local benefit. Capacity strengthening efforts, aimed at improving institutional support for ethical conduct of human subjects research, must continue to be supported by wealthier nations.     

Māori Culture on Stage: Authenticity and Identity in Tourist Interactions1

Cultural tourism is often described as inciting visited populations to adapt elements of their culture to the visitors' tastes instead of displaying their real way of life or identity. Even when researchers adopt a constructivist approach to authenticity, they often assume that it is defined according to the criteria or expectations of the tourists. In this paper, I analyse three Māori cultural shows in New Zealand, and explore the way cultural authenticity is defined in tourist interactions. I review the arguments in favour of rejecting the opposition between ‘inauthentic’ staged culture and ‘authentic’ daily life. My study tends to indicate that if authenticity is better described as a social construction, the host society might be more active in this process than visitors.     

Spatial and Temporal Considerations in Restoring Habitat for Wildlife

An accumulated body of theory and empirical evidence suggests that habitat selection by animals is a scale‐dependent, hierarchical process. Hierarchy theory predicts that habitat suitability is influenced by the interaction of factors at multiple spatial scales from the microsite to the landscape and that higher‐order factors impose constraints at lower levels. For instance, large‐scale factors such as landscape context may make a site unsuitable for a species even if the vegetation structure and composition are appropriate. In addition, the spatial arrangement of habitat elements at all scales must be considered when planning restoration efforts. For example, the presence of snags does not ensure that the site will be suitable for snag‐dependent species. The size, age, and spacing of snags and their juxtaposition to other habitat elements must also be considered. Finally, all habitats are dynamic, and therefore the ecological processes that contribute to those dynamics must be maintained or suitable substitutes included in the recovery plan. When considering restoring habitat for wildlife, we recommend that managers: (1) identify the wildlife species they want to target for restoration efforts, (2) consider the size and landscape context of the restoration site and whether it is appropriate for the target species, (3) identify the habitat elements that are necessary for the target species, (4) develop a strategy for restoring those elements and the ecological processes that maintain them, and (5) implement a long‐term monitoring program to gauge the success of the restoration efforts.     

Tracing and control of raw materials sourcing for vaccine manufacturers

The control of the raw materials used to manufacture vaccines is mandatory; therefore, a very clear process must be in place to guarantee that raw materials are traced. Those who make products or supplies used in vaccine manufacture (suppliers of culture media, diagnostic tests, etc.) must apply quality systems proving that they adhere to certain standards. ISO certification, Good Manufacturing Practices for production sites and the registration of culture media with a ‘Certificate of Suitability’ from the European Directorate for the Quality of Medicines and Healthcare are reliable quality systems pertaining to vaccine production. Suppliers must assure that each lot of raw materials used in a product that will be used in vaccine manufacture adheres to the level of safety and traceability required. Incoming materials must be controlled in a single ‘Enterprise Resource Planning’ system which is used to document important information, such as the assignment of lot number, expiration date, etc. Ingredients for culture media in particular must conform to certain specifications. The specifications that need to be checked vary according to the ingredient, based on the level of risk.The way a raw material is produced is also important, and any aspect relative to cross-contamination, such as the sanitary measures used in producing and storing the raw material must be checked as well. In addition, suppliers can reduce the risk of viral contamination of raw materials by avoiding purchases in countries where a relevant outbreak is currently declared.     

Challenges in constructing statistically based structure-activity relationship models for developmental toxicity

Regulatory agencies are increasingly called upon to review large numbers of environmental contaminants that have not been characterized for their potential to pose a health risk. Additionally, there is special interest in protecting potentially sensitive subpopulations and identifying developmental toxicants that may be present in the environment. Thus, there is an urgent need for efficient methods to screen large numbers of chemicals for their potential to pose a developmental hazard. One potential screening method involves the use of statistically based structure-activity relationship (SAR) tools to predict activity of untested chemicals. Such systems rely on statistical analyses to discern relationships between structure and activity for a training set of substances. Predictions can then be made for an untested substance as long as its structural features are encompassed by chemicals of the training set. In theory, such systems could assist regulatory agencies in their screening efforts; however, to date, there has been little independent evaluation of these tools for this use. To contribute to such an evaluation, the International Life Sciences Institute Risk Science Institute (ILSI RSI) convened a Working Group to examine methodology used to construct statistically based SAR systems for developmental toxicity. This document reports on the deliberations of the Working Group, which concluded that an improved process is needed for utilizing developmental toxicity data in the construction of statistically based SAR models. The process must be objective, reproducible, rational and transparent. Moreover, it must be informed by the expertise of developmental toxicologists and biologists and must be subject to peer review.     

Levers for Language Growth: Characteristics and Predictors of Language Trajectories between 4 and 7 Years

Background

Evidence is required as to when and where to focus resources to achieve the greatest gains for children’s language development. Key to these decisions is the understanding of individual differences in children’s language trajectories and the predictors of those differences. To determine optimal timing we must understand if and when children’s relative language abilities become fixed. To determine where to focus effort we must identify mutable factors, that is those with the potential to be changed through interventions, which are associated with significant differences in children’s language scores and rate of progress.

Methods

Uniquely this study examined individual differences in language growth trajectories in a population sample of children between 4 and 7 years using the multilevel model for change. The influence of predictors, grouped with respect to their mutability and their proximity to the child (least-mutable, mutable-distal, mutable-proximal), were estimated.

Results

A significant degree of variability in rate of progress between 4 and 7 years was evident, much of which was systematically associated with mutable-proximal factors, that is, those factors with evidence that they are modifiable through interventions with the child or family, such as shared book reading, TV viewing and number of books in the home. Mutable-distal factors, such as family income, family literacy and neighbourhood disadvantage, hypothesised to be modifiable through social policy, were important predictors of language abilities at 4 years.

Conclusions

Potential levers for language interventions lie in the child’s home learning environment from birth to age 4. However, the role of a family’s material and cultural capital must not be ignored, nor should the potential for growth into the school years. Early Years services should acknowledge the effects of multiple, cascading and cumulative risks and seek to promote child language development through the aggregation of marginal gains in the pre-school years and beyond.     

Why nation-states and journalists can't teach people to be healthy: power and pragmatic miscalculation in public discourses on health

This article analyzes how Venezuelan public health officials collaborated with journalists in producing information about cholera in January-December 1991. It uses Michael Warner's (2002) observation that such public discourse involves a contradiction: it must project the image of reaching an actually existing public at the same time that it creates multiple publics as it circulates. The analysis explores the language ideologies that hide complex sets of practices, networks, and material conditions that shape how public discourses circulate. At the same time that epidemiologists targeted poor barrio residents, street vendors of food and drink, and indigenous people as being "at high risk," health education messages pictured women in well-equipped kitchens demonstrating cholera prevention measures. The gap between these ideal audiences and the discrepant publics created by their circulation limited the effectiveness of prevention efforts and created a substantial chasm between public health institutions and the publics they sought to reach.     

The green beards of language

Language transfers information on at least three levels; (1) what is said, (2) how it is said (what language is used), and, (3) that it is said (that speaker and listener both possess the ability to use language). The use of language is a form of honest cooperation on two of these levels; not necessarily on what is said, which can be deceitful, but always on how it is said and that it is said. This means that the language encoding and decoding systems had to evolve simultaneously, through mutual fitness benefits. Theoretical problems surrounding the evolution of cooperation disappear if a recognition system is present enabling cooperating individuals to identify each other – if they are equipped with “green beards”. Here, I outline how both the biological and cultural aspects of language are bestowed with such recognition systems. The biological capacities required for language signal their presence through speech and understanding. This signaling cannot be invaded by “false green beards” because the traits and the signal of their presence are one and the same. However, the real usefulness of language comes from its potential to convey an infinite number of meanings through the dynamic handling of symbols – through language itself. But any specific language also signals its presence to others through usage and understanding. Thus, languages themselves cannot be invaded by “false green beards” because, again, the trait and the signal of its presence are one and the same. These twin green beards, in both the biological and cultural realms, are unique to language.