Weather impacts on leisure activities in Halifax,Nova Scotia

The aim of this study was to investigate the impact of daily atmospheric weather conditions on daily leisure activity engagement, with a focus on physically active leisure. The methods capitalize on time diary data that were collected in Halifax, Nova Scotia to calculate objective measures of leisure activity engagement. Daily meteorological data from Environment Canada and daily sunrise and sunset times from the National Research Council of Canada are used to develop objective measures of the natural atmospheric environment. The time diary data were merged with the meteorological data in order to quantify the statistical association between daily weather conditions and the type, participation rate, frequency, and duration of leisure activity engagement. The results indicate that inclement and uncomfortable weather conditions, especially relating to thermal comfort and mechanical comfort, pose barriers to physically active leisure engagement, while promoting sedentary and home-based leisure activities. Overall, daily weather conditions exhibit modest, but significant, effects on leisure activity engagement; the strongest associations being for outdoor active sports and outdoor active leisure time budgets. In conclusion, weather conditions influence the type, participation rate, frequency, and duration of leisure activity engagement, which is an important consideration for health-promotion programming.     

Community engagement in global health research that advances health equity

Community engagement is gaining prominence in global health research. So far, a philosophical rationale for why researchers should perform community engagement during such research has not been provided by ethics scholars. Its absence means that conducting community engagement is still often viewed as no more than a ‘good idea’ or ‘good practice’ rather than ethically required. In this article, we argue that shared health governance can establish grounds for requiring the engagement of low‐ and middle‐income country (LMIC) community members in global health research, where such research aims to help reduce health disparities. This philosophical basis has important implications for the ethical goals ascribed to engagement and the approach adopted to undertake it. We suggest the ethical goals of engagement in equity‐oriented global health research should include: (a) generating research topics and questions that reflect the key problems disadvantaged groups face in accessing healthcare, services and broader social determinants of health and (b) promoting the translation of research findings into policy and practice in ways that benefit the health of disadvantaged groups. We propose engagement practice should have the following features: deliberation with LMIC community members to make a range of project decisions, beginning with setting research topics and questions; inclusion of members of disadvantaged groups and those with the power to change policy and practice to benefit them; and purposeful structuring of deliberations to minimize the impact of power disparities between LMIC community members. Finally, we reflect on how these features differ from those typical of much current community engagement practice in LMICs.     

Sensitivity of the Welfare Quality® broiler chicken protocol to differences between intensively reared indoor flocks: which factors explain overall classification?

There is a large demand for holistic welfare assessment systems that result in a singular balanced summary of welfare. The Welfare Quality® (WQ) broiler protocol summarizes 18 welfare measures into four principles (‘good feeding’, ‘good housing’, ‘good health’ and ‘appropriate behaviour’), which are then integrated into one overall category (‘excellent’, ‘enhanced’, ‘acceptable’ or ‘not classified’). But the protocol is time consuming which hampers implementation. Furthermore, WQ’s aim to assess animal welfare in a wide range of husbandry systems may decrease its ability to discriminate between flocks from the same system. We applied the protocol in the context of intensive indoor rearing to assess whether it discriminated sufficiently between flocks, could be shortened without losing essential information, and provided a balanced summary of welfare. The vast majority of the flocks (88%) received the same overall classification (acceptable) whilst all other flocks received an adjacent classification (enhanced), suggesting poor discriminative capacity. For 95% of the flocks overall classification was explained by two measures only (‘drinker space’ and ‘stocking density’). A system based on these two measures would reduce assessment time from 3.5 h to a few minutes. However, both measures’ validity can be questioned as they are risk factors for poor welfare rather than animal-based outcome measures and they suffer from methodological weaknesses. Furthermore, the possibility for such an extreme simplification raises doubts on whether the overall classification reflects a balanced summary of different welfare aspects. In line with this, overall classification was not affected by replacing single measures within the ‘good health’ and ‘appropriate behaviour’ principles with realistically attainable minima or maxima for intensively reared flocks. Even replacing either of these two principles entirely with their realistically obtainable minimum or maximum did not affect classification. Such insensitivity to change may discourage attempts to improve the welfare of intensively reared flocks when assessments are made based on the overall classification. This calls for an adjustment of the classification system, which is currently being developed by the Welfare Quality Network.     

Low-amplitude trapezius activity in work and leisure and the relation to shoulder and neck pain.

The aim of this study is to obtain evidence supporting or negating the hypothesis that muscle pain is associated with sustained activation of low-threshold motor units. Long-term surface electromyographic (EMG) recordings of trapezius activity pattern were related to subjectively reported shoulder and neck pain in work and leisure. Recordings from 118 female subjects (73 recorded both during work and leisure) were analyzed. Computer operators, secretaries, and health care and retail workers were represented in the material. The recordings were calibrated by the root-mean-square-detected response at maximal voluntary contraction (%maximum EMG). The analysis was performed by quantifying duration and amplitude of surface EMG activity exceeding 2% maximum EMG ("EMG bursts"). Three response categories were defined by duration of the burst periods during work: low- (<50%), intermediate- (50-70%), and high-response (>70%) groups. Shoulder and neck pain was assessed by hourly visual analog score throughout work and leisure and by pain score for the last 6 mo. Shoulder and neck pain was higher at work than leisure for subjects with long-term pain in both the high- and the low-response groups. Persistent pain, defined by the 6-mo score, was more prevalent in the high- than the low- and intermediate-response groups (73 vs. 37%); relative risk was 2.0. Trapezius activity was reduced from work to leisure for the high- but not the low-response group. The activity pattern is consistent with low-threshold motor unit overexertion for the high- but not the low-response group. We speculate that different mechanisms of muscle pain causation, dependent and independent of motor activity pattern, coexist.     

Injuries to primary school pupils and secondary school students during physical education classes and in their leisure time

The study aimed to establish the frequency of injuries in primary and secondary schools during leisure time and physical education classes in school as well as in group and individual sports. The sample included 2842 pupils from nine primary schools and 1235 students from five secondary schools in Slovenia. The data were processed with the SPSS statistical software package and the frequencies and Crosstabs were calculated. The results showed that substantially more pupils and students were injured in their leisure time than during physical education classes. Girls were more frequently injured in group and individual sports practiced during physical education classes and in individual sports practiced in their leisure time, whereas boys suffered more injuries in group sports practiced in their leisure time. As regards group sports, pupils and students were most frequently injured while playing football in their leisure time whereas, during physical education classes, they suffered most injuries in volleyball, followed closely by basketball and football; as regards individual sports, pupils and students were most frequently injured while cycling and rollerblading in their leisure time, whereas during physical education classes they suffered most injuries in athletics.     

The IDIP framework for assessing protein function and its application to the prion protein

The quest to determine the function of a protein can represent a profound challenge. Although this task is the mandate of countless research groups, a general framework for how it can be approached is conspicuously lacking. Moreover, even expectations for when the function of a protein can be considered to be ‘known’ are not well defined. In this review, we begin by introducing concepts pertinent to the challenge of protein function assignments. We then propose a framework for inferring a protein's function from four data categories: ‘inheritance’, ‘distribution’, ‘interactions’ and ‘phenotypes’ (IDIP). We document that the functions of proteins emerge at the intersection of inferences drawn from these data categories and emphasise the benefit of considering them in an evolutionary context. We then apply this approach to the cellular prion protein (PrP^C), well known for its central role in prion diseases, whose function continues to be considered elusive by many investigators. We document that available data converge on the conclusion that the function of the prion protein is to control a critical post-translational modification of the neural cell adhesion molecule in the context of epithelial-to-mesenchymal transition and related plasticity programmes. Finally, we argue that this proposed function of PrP^C has already passed the test of time and is concordant with the IDIP framework in a way that other functions considered for this protein fail to achieve. We anticipate that the IDIP framework and the concepts analysed herein will aid the investigation of other proteins whose primary functional assignments have thus far been intractable.     

The Nation‐State,Public Education,and the Logic of Migration: Chinese Students in Hungary

Public education remains the nation‐state's foremost instrument of forging citizens. But the emergence of ‘international education’, a system explicitly based on the ideology of globality and outside the purview of national curricula, provides a way to circumvent the citizen‐making machine. This article, based on fieldwork among Chinese secondary school students in Hungary, considers the interaction between ‘international education’ and transnational migrants in a nation‐state whose public education, as the state itself, has little interest in the ‘integration’ of non‐natives.     

Socioeconomic position and incidence of colorectal cancer in the Swedish population

BackgroundThe association between socioeconomic position and incidence of colorectal cancer is inconsistent and differs by global region. We aimed to clarify this association in the Swedish population.MethodsWe conducted a population-based open cohort study using data from Swedish national registers. We included all individuals, aged ≥30 years, residing in Sweden between 1993 and 2010. Socioeconomic position was indicated by (1) highest educational level (five groups), and (2) disposable income (quintiles). We used Poisson regression to estimate incidence rate ratios (IRR) and 95% confidence intervals (95% CI) of colon and rectal cancer, and colon and rectal dysplasia.ResultsIn total, 97,827,817 person-years were accumulated and 82,686 cases of colorectal cancer were diagnosed. Compared to men with ‘higher secondary’ education, the adjusted IRRs (95% CI) of rectal cancer in men with ‘primary or less’, ‘lower secondary’, ‘lower university’ or ‘higher university’ education were: 1.06 (1.00, 1.11), 1.05 (0.99, 1.10), 0.96 (0.89, 1.03), and 0.92 (0.86, 0.98), respectively. In women, the corresponding figures were: 1.04 (0.95, 1.14), 1.03 (0.94, 1.13), 0.92 (0.82, 1.02) and 0.92 (0.82, 1.02). Disposable income was not associated with rectal cancer incidence. Adjusted IRRs of colon cancer did not differ between levels of education or disposable income overall or for specific colon sub-sites. Neither education nor disposable income was consistently associated with incidence of colon or rectal dysplasia.ConclusionsPrevention strategies for colon cancer should be applicable to individuals regardless of their socioeconomic position. However, factors conferred by education, e.g., health awareness, may be important for approaches aiming to reduce inequalities in incidence of rectal cancer. Further evaluation of cancer prevention and health promotion strategies among less educated groups is warranted.     

Individuals and groups in evolution: Darwinian pluralism and the multilevel selection debate

Outlined here is an updated review of the long-standing ‘kin selection vs group selection’ debate. Group selection is a highly contentious concept, scientifically and philosophically. In 2012, Dawkins’ attack against Wilson’s latest book about eusociality concentrated all the attention on group selection and its mutual exclusivity with respect to inclusive fitness theory. Both opponents seem to be wrong, facing the general consensus in the field, which favours a pluralistic approach. Historically, despite some misunderstandings in current literature, such a perspective is clearly rooted in Darwin’s writings, which suggested a plurality of levels of selection and a general view that we propose to call ‘imperfect selfishness’. Today, the mathematically updated hypothesis of group selection has little to do with earlier versions of ‘group selection’. It does not imply ontologically unmanageable notions of ‘groups’. We propose here population structure as the main criterion of compatibility between kin selection and group selection. The latter is now evidently a pattern among others within a more general ‘multilevel selection’ theory. Different explanations and patterns are not mutually exclusive. Such a Darwinian pluralism is not a piece of the past, but a path into the future. A challenge in philosophy of biology will be to figure out the logical structure of this emerging pluralistic theory of evolution in such contentious debates.     

Sleep problems and computer use during work and leisure: Cross-sectional study among 7800 adults

Previous studies linked heavy computer use to disturbed sleep. This study investigates the association between computer use during work and leisure and sleep problems in working adults. From the 2010 round of the Danish Work Environment Cohort Study, currently employed wage earners on daytime schedule (N?=?7883) replied to the Bergen insomnia scale and questions on weekly duration of computer use. Results showed that sleep problems for three or more days per week (average of six questions) were experienced by 14.9% of the respondents. Logistic regression analyses, controlled for gender, age, physical and psychosocial work factors, lifestyle, chronic disease and mental health showed that computer use during leisure for 30 or more hours per week (reference 0–10 hours per week) was associated with increased odds of sleep problems (OR 1.83 [95% CI 1.06–3.17]). Computer use during work and shorter duration of computer use during leisure were not associated with sleep problems. In conclusion, excessive computer use during leisure – but not work – is associated with sleep problems in adults working on daytime schedule.     

Graph-based impact analysis as a framework for incorporating practitioner knowledge in dairy herd health management

Production diseases in dairy cows are multifactorial, which means they emerge from complex interactions between many different farm variables. Variables with a large impact on production diseases can be identified for groups of farms using statistical models, but these methods cannot be used to identify highly influential variables in individual farms. This, however, is necessary for herd health planning, because farm conditions and associated health problems vary largely between farms. The aim of this study was to rank variables according to their anticipated effect on production diseases on the farm level by applying a graph-based impact analysis on 192 European organic dairy farms. Direct impacts between 13 pre-defined variables were estimated for each farm during a round-table discussion attended by practitioners, that is farmer, veterinarian and herd advisor. Indirect impacts were elaborated through graph analysis taking into account impact strengths. Across farms, factors supposedly exerting the most influence on production diseases were ‘feeding’, ‘hygiene’ and ‘treatment’ (direct impacts), as well as ‘knowledge and skills’ and ‘herd health monitoring’ (indirect impacts). Factors strongly influenced by production diseases were ‘milk performance’, ‘financial resources’ and ‘labour capacity’ (directly and indirectly). Ranking of variables on the farm level revealed considerable differences between farms in terms of their most influential and most influenced farm factors. Consequently, very different strategies may be required to reduce production diseases in these farms. The method is based on perceptions and estimations and thus prone to errors. From our point of view, however, this weakness is clearly outweighed by the ability to assess and to analyse farm-specific relationships and thus to complement general knowledge with contextual knowledge. Therefore, we conclude that graph-based impact analysis represents a promising decision support tool for herd health planning. The next steps include testing the method using more specific and problem-oriented variables as well as evaluating its effectiveness.     

Review: Animal health and sustainable global livestock systems

This paper discusses the sustainability of livestock systems, emphasising bidirectional relations with animal health. We review conventional and contrarian thinking on sustainability and argue that in the most common approaches to understanding sustainability, health aspects have been under-examined. Literature review reveals deep concerns over the sustainability of livestock systems; we recognise that interventions are required to shift to more sustainable trajectories, and explore approaches to prioritising in different systems, focusing on interventions that lead to better health. A previously proposed three-tiered categorisation of ‘hot spots’, ‘cold spots’ and ‘worried well’ animal health trajectories provides a mental model that, by taking into consideration the different animal health status, animal health risks, service response needs and key drivers in each system, can help identify and implement interventions. Combining sustainability concepts with animal health trajectories allows for a richer analysis, and we apply this to three case studies drawn from North Africa and the Middle East; Bangladesh; and the Eastern Cape of South Africa. We conclude that the quest for sustainability of livestock production systems from the perspective of human and animal health is elusive and difficult to reconcile with the massive anticipated growth in demand for livestock products, mainly in low- and middle-income countries, as well as the aspirations of poor livestock keepers for better lives. Nevertheless, improving the health of livestock can contribute to health sustainability both through reducing negative health impacts of livestock and increasing efficiency of production. However, the choice of the most appropriate options must be under-pinned by an understanding of agro-ecology, economy and values. We argue that a new pillar of One Health should be added to the three traditional sustainability pillars of economics, society and environment when addressing livestock systems.     

Mapping the complexity of ecological models

We propose to define the complexity of an ecological model as the statistical complexity of the output it produces. This allows for a direct comparison between data and model complexity. Working with univariate time series, we show that this measure ‘blindly’ discriminates among the different dynamical behaviours a model can exhibit. We then search a model parameter space in order to segment it into areas of different dynamical behaviour and calculate the maximum complexity a model can generate. Given a time series, and the problem of choosing among a number of ecological models to study it, we suggest that models whose maximum complexity is lower than the time series complexity should be disregarded because they are unable to reconstruct some of the structures contained in the data. Similar reasoning could be used to disregard models’ subdomains as well as areas of unnecessary high complexity. We suggest that model complexity so defined better captures the difficulty faced by a user in managing and understanding the behaviour of an ecological model than measures based on a model ‘size’.     

To see that which cannot be seen: ontological differences and public health policies in Southern Chile

In this article, I explore different visual practices performed by Pehuenche Indigenous healers and state public health professionals in Southern Chile. While non‐Indigenous health workers seek to make ‘traditional’ Pehuenche healing visible within or alongside their own ‘modern’ practices, Pehuenche people are concerned with making visible the evil spirits whose ‘eating’ of persons produces illness. Focusing in particular on different healing practices triggered by the existence of Pehuenche spiritual illnesses that are ‘seen’ by both Indigenous healers and state professionals, this article discusses how different ontologies ground differences between the Indigenous healers and what they ‘see’; as well as how a broader and substantive binary between Pehuenche and non‐Pehuenche realities goes above and beyond these multiplicities. By exploring and discussing the endurance of Pehuenche cosmo‐political relations in a world inhabited by visible and invisible eaters, I hope to create awareness about how a failure to recognize these different realities limits current multicultural policies in Southern Chile, and Indigenous health policies more broadly. At a more theoretical level, the following ethnographic account sheds light on unresolved tensions between the ways ontological difference has been conceptualized within the so‐called ‘ontological turn’ in anthropology and within the field of Science and Technology Studies (STS).     

Social mobility of ethnic minority students in Laos

Idealistically speaking, schools are engines for upward social mobility. Education for ethnic minorities in Laos was set up to achieve nationalist, political, economic and sociocultural goals of ‘equity’ and ‘equality’. It was hoped that education would shift ethnic minorities from a lifestyle based on superstitious beliefs to a modern one, so that they could participate and enjoy ‘equality’ through educational equity. The purpose of this paper is to provide a case study of how equality as a promise in education has impacted on students’ upward mobility, particularly the political discourse of the ‘big man’. This paper explores social mobility provided by national education for ethnic minorities through boarding schooling. It finds that such education has yet to reposition ethnic minorities into the ethnic Lao sociocultural hierarchy. As a result, regardless of their educational success, students are still ranked as ‘ethnic minorities’ and as being ‘poor’ in the eyes of urban students, middle class and rich students, and the ethnic Lao elite.     

生态系统休闲游憩价值评估——以北京密云区为例

作为生态产品总值核算的重要内容,生态系统文化服务主要包括休闲游憩、旅游康养与景观增值三个核算内容,但受公共产品性质的影响,休闲游憩服务缺乏市场价值,因此目前的研究很少涉及对生态系统休闲游憩价值的评估。而随着公园绿地等区域被广泛利用,其能为人们带来的休闲游憩服务也逐渐成为生态系统文化服务中不可忽视的重要组成部分。因此以北京密云区的公园绿地、滨水带与山地健身区为研究对象,运用替代成本法与支付意愿法对生态系统的休闲游憩价值进行评估与比较。结果表明,替代成本法评估的结果相对更合理;公园绿地、滨水带与山地健身区的休闲游憩价值分别为2.93亿元、4.54亿元、2.78亿元;密云区生态系统的休闲游憩价值为10.25亿元,其中费用成本6.69亿元,时间成本3.56亿元。     

Synthetic gene drives as an anthropogenic evolutionary force

Genetic drive represents a fundamental evolutionary force that can exact profound change to the genetic composition of populations by biasing allele transmission. Herein I propose that the use of synthetic homing gene drives, the human-mediated analog of endogenous genetic drives, warrants the designation of ‘genetic welding’ as an anthropogenic evolutionary force. Conceptually, this distinction parallels that of artificial and natural selection. Genetic welding is capable of imposing complex and rapid heritable phenotypic change on entire populations, whether motivated by biodiversity conservation or public health. Unanticipated possible long-term evolutionary outcomes, however, demand further investigation and bioethical consideration. The emerging importance of genetic welding also compels our explicit recognition of genetic drive as an addition to the other four fundamental forces of evolution.     

The weighted groundwater health index: Improving the monitoring and management of groundwater resources

Increased global demand for groundwater has resulted in the need to measure and monitor this resource. Rather than monitoring groundwater simply though water chemistry and levels, which provides a ‘snapshot’ of the conditions at any given time, a more holistic approach to managing groundwater resources and their changes over time is needed. Korbel & Hose (2011) introduced the first structured framework for measuring groundwater health – the Groundwater Health Index (GHI). This multimetric, two-tiered framework uses biotic and abiotic components of the groundwater ecosystem to measure and identify ecosystem health. The framework can be used to classify impacted from non-impacted groundwaters, however it has certain limitations. With increased research and associated knowledge of groundwater ecosystems in recent times, it is now timely to attempt to build on the GHI framework.This paper refines and improves the GHI by incorporating a weighting system to account for natural factors contributing to variations in biotic distribution and is tested on data within four geologically similar alluvial aquifers in intensively irrigated agricultural areas of New South Wales and Queensland, Australia. Using a combination of microbial, stygofaunal, water chemistry and environmental indicators, the ‘weighted GHI’ framework was able to discriminate three distinct ecosystem health classifications; that of ‘similar to reference’(displaying reference-like condition) ‘mild deviation from reference’ (sites failing to meet between 2 and 3 benchmarks) and ‘major deviation from reference’ (sites with more than four benchmarks exceeded). The framework indicated that groundwater health deviated from reference condition in all four catchments studied, with irrigated sites consistently displaying deviations from reference ecosystem health. Tier 2 benchmarks were set using results from the Gwydir River, and were tested on the adjacent Namoi River catchment, the Condamine and Lower Macquarie catchments. Results indicated that ecosystem health benchmarks may be associate with aquifer typology, rather than being applicable only for local areas.     

Opt‐in or opt‐out to increase organ donation in South Africa? Appraising proposed strategies using an empirical ethics analysis

Utilising empirical ethics analysis, we evaluate the merits of systems proposed to increase deceased organ donation in South Africa (SA). We conclude that SA should maintain its soft opt‐in policy, and enhance it with ‘required transplant referral’ in order to maximise donor numbers within an ethically and legally acceptable framework. In SA, as is the case worldwide, the demand for donor organs far exceeds the supply thereof. Currently utilising a soft opt‐in system, SA faces the challenge of how to increase donor numbers in a context which is imbued with inequalities in access to healthcare, multiplicitous personal beliefs and practices, distrust of organ transplant and varying levels of education and health literacy. We argue that a hard opt‐in, opt‐out or mandated consent system would be problematic, and we present empirical data from Gauteng Province illustrating barriers to ethically sound practice in soft consent systems. Ultimately, we argue that in spite of some limitations, a soft opt‐in system is most realistic for SA because its implementation does not require extensive public education campaigns at national level, and it does not threaten to further erode trust at a clinical level. However, to circumvent some of the clinical‐level barriers identified in our empirical study, we propose a contextually sensitive option for “enabling” soft opt‐in through “required transplant referral”. We argue that this system is legally defensible, enhances ethical practice and could also increase donor numbers as it has in many other countries.