Intérêt de l’introduction à la nomenclature du test de détection des HPV

Le cancer du col de l’utérus reste un problème de santé publique puisque 900 000 nouveaux cas sont diagnostiqués chaque année de par le monde [Luthra] et il est responsable en France de plus de 1600 décès par an. Pourtant, depuis plus de 40 ans, le dépistage de masse des précurseurs du cancer invasif est tout à fait réalisable et le traitement des anomalies cervicales pré-invasives amène généralement à la guérison.     

Vérification et utilisation d’un test élaboré de préselection des plantes tolérantes aux sels, à partir de la teneur en proline

This paper deals with the verification of a test of crop seedlings for the determination of the salt tolerance. There is a typical concentration of NaCl in the culture medium above which an enhancement of the free proline content is induced (critical point, critical concentration). The determination of this critical concentration in 19 cultivars of crop plants has proved that plants grown in aride areas (i.e. Hordeum, Triticum durum) have a critical concentration that is by about 50 to 80 mmol l^-1 of NaCl higher than that of plants grown in more humid regions (i.e. Triticum aestivum). The critical concentration is not influenced by pH changes of the external solution. Calcium application leads to an enhancement of tolerance. The different increases of growth and fresh mass of salt sensitive and salt tolerant plants selected by this test system proved the aptitude of the critical concentration in culture medium for proline augmentation as a test parameter.     

Using likelihood to test for Lévy flight search patterns and for general power-law distributions in nature

1. Ecologists are obtaining ever-increasing amounts of data concerning animal movement. A movement strategy that has been concluded for a broad variety of animals is that of Lévy flights, which are random walks whose step lengths come from probability distributions with heavy power-law tails. 2. The exponent that parameterizes the power-law tail, denoted micro, has repeatedly been found to be within the Lévy range of 1 < micro 相似文献   

Génétique moléculaire des dysgénésies testiculaires

The first step of male differentiation is the testis determination which is genetically controled. The key role of SRY gene is now established. However, a number of clinical and genetic data favoured the role of other genes taking place upstream or downstream SRY. Most of 46, XX males possess a translocated SRY gene and thus develop testis, but SRY gene is not found in 10% of such patients. Likewise, the molecular study of 46, XY females participated in the identification of SRY as testis determining factor, but 80% of XY gonadal dysgenesis are not explained by an abnormality of SRY gene. Several clinical situations permitted to suspect the role of autosomal (chromosome 1, 9, 10 17 …) and X chromosome loci in the pathology of sex determination. Some recent works concern, in particular, the testis determining factor of the X chromosome (TDF-X) that could act as a repressor of the testis differentiation. In conclusion, molecular mechanisms of sexual determination appear to be much complex, involving probably several genes in a pathway that remain to be elucidated.     

Cancer et Hérédité

Sans résumé     

Chromosomes et hétérochromosomes de ténébrionidés

Sans résumé Avec 81 figures dans le texte     

Systématique moléculaire des Mélitées

The holarctic subfamily Melitaeinae of Nymphalid butterflies (old genus Melitaea Hbn.) has been split into various genera by morphological systematics, but this division has been debated. This work presents the results of a preliminary survey of European taxa using two types of molecular criteria: analysis of enzyme variation by electrophoresis (19 loci) and sequencing of a mtDNA fragment (ND1 gene). The information provided by both kinds of markers are largely congruent. The division of the subfamily into two monophyletic lines corresponding to the genera Euphyryas s. 1. and Melitaea s. l. is validated. The subsequent division of the former genus into two units, Eurodryas and Hypodryas is also confirmed by molecular criteria. Inside rhe old genus Melitaea, a monophyletic assemblage, corresponding to the ‘Mellicta group’ is disclosed, but the phylogeny of the other species of the group is confused. Uniting them in a ‘Didymaeformia group’ or in a genus Melitaea s. str. risks rhe generation of a paraphyletic assemblage. It remains to be determined whether or not these results are due to insufficient resolution, or whether they reflecr a real evolutionary pattern