共查询到20条相似文献,搜索用时 15 毫秒
1.
Background
The p49/STRAP (or SRFBP1) protein was recently identified in our laboratory as a cofactor of serum response factor that contributes to the regulation of SRF target genes in the heart. 相似文献2.
Background
The relative efficacy of antiemetics for the treatment of postoperative nausea and vomiting (PONV) is poorly understood. 相似文献3.
Characterization of a filamentous biofilm community established in a cellulose-fed microbial fuel cell 总被引:1,自引:0,他引:1
Background
Microbial fuel cells (MFCs) are devices that exploit microorganisms to generate electric power from organic matter. Despite the development of efficient MFC reactors, the microbiology of electricity generation remains to be sufficiently understood. 相似文献4.
Claudia Schiffczyk Barbara Romero Christina Jonas Constanze Lahmeyer Friedemann Müller Matthias W Riepe 《BMC neurology》2010,10(1):48
Background
Quality of life (QoL) is increasingly used to characterize the impact of disease and the efficacy of interventions. 相似文献5.
Background
Secretory carcinoma of the male breast (juvenile carcinoma) is a rare neoplasm. Only a few cases have been reported in the literature. 相似文献6.
A. Nur K. Hirota H. Yumoto K. Hirao D. Liu K. Takahashi K. Murakami T. Matsuo R. Shu Y. Miyake 《Journal of applied microbiology》2013,115(1):260-270
Aims
The aim of this study was to clarify the effects of homologous and heterologous extracellular DNAs (eDNAs) and histone‐like DNA‐binding protein (HLP) on Streptococcus intermedius biofilm development and rigidity.Methods and Results
Formed biofilm mass was measured with 0·1% crystal violet staining method and observed with a scanning electron microscope. The localizations of eDNA and extracellular HLP (eHLP) in formed biofilm were detected by staining with 7‐hydoxyl‐9H‐(1,3‐dichloro‐9,9‐dimethylacridin‐2‐one) and anti‐HLP antibody without fixation, respectively. DNase I treatment (200 U ml?1) markedly decreased biofilm formation and cell density in biofilms. Colocalization of eHLP and eDNA in biofilm was confirmed. The addition of eDNA (up to 1 μg ml?1) purified from Strep. intermedius, other Gram‐positive bacteria, Gram‐negative bacteria, or human KB cells into the Strep. intermedius culture increased the biofilm mass of all tested strains of Strep. intermedius, wild‐type, HLP‐downregulated strain and control strains. In contrast, the addition of eDNA (>1 μg ml?1) decreased the biofilm mass of all Strep. intermedius strains.Conclusions
These findings demonstrated that eDNA and eHLP play crucial roles in biofilm development and its rigidity.Significance and Impact of the Study
eDNA‐ and HLP‐targeting strategies may be applicable to novel treatments for bacterial biofilm‐related infectious diseases. 相似文献7.
Kenneth J Warrington Elena P Jarpa Cynthia S Crowson Leslie T Cooper Gene G Hunder Eric L Matteson Sherine E Gabriel 《Arthritis research & therapy》2009,11(2):R50-6
Introduction
The present study was conducted to determine whether patients with polymyalgia rheumatica (PMR) are at an increased risk of peripheral arterial disease (PAD). 相似文献8.
Reversing expansion of Calamagrostis epigejos in a grassland biodiversity hotspot: Hemiparasitic Rhinanthus major does a better job than increased mowing intensity 下载免费PDF全文
Questions
Can hemiparasitic Rhinanthus major originating from a local population suppress the competitive clonal grass Calamagrostis epigejos and reverse its expansion in species‐rich semi‐natural grasslands? Does sowing seeds of R. major facilitate restoration of target meadow vegetation? Is R. major more beneficial for biodiversity restoration/conservation than increased mowing intensity, a conventional measure to suppress C. epigejos?Location
?ertoryje National Nature Reserve, Bílé Karpaty (White Carpathians) Protected Landscape Area, Czech Republic.Methods
We conducted a before‐after‐control‐impact experiment in meadow patches heavily infested by C. epigejos: eight blocks, each containing four plots with four treatment combinations: (1) traditional management, i.e. mowing once in summer, (2) mowing in summer and autumn (3) mowing in summer and seed sowing of R. major, (4) mowing in summer and autumn and seed sowing of R. major. Above‐ground biomass of C. epigejos and vegetation composition of each of the plots were monitored every year from 2013 to 2016. To assess the effects of treatments, we analysed biomass production of C. epigejos, herb layer cover and vegetation composition.Results
Both sowing R. major and an additional autumn meadow cut significantly suppressed C. epigejos. Their effects were additive and of comparable size. Both treatments also had significant but markedly different effects on community composition. Rhinanthus major facilitated directional community composition change towards the regional Brachypodio‐Molinetum meadows. In contrast, increased mowing intensity significantly decreased frequency of threatened species, which however may have also been influenced by R. major.Conclusions
Sowing of autochthonous R. major seeds was demonstrated as an efficient tool to suppress C. epigejos and facilitate community restoration. It can be combined with an additional meadow cut to further accelerate decline of the grass. The additional cut should however be used as a short‐term practice (1–2 years) only to minimize potential negative effects of its long‐term application on some threatened plant species. The effects of R. major are comparable to those of Rhinanthus alectorolophus reported previously. As a species occurring naturally in species‐rich dry grasslands, R. major has a broader and longer‐term application potential than R. alectorolophus in ecological restoration and conservation of these communities. 相似文献9.
Karen M Moody Lawrence B Schonberger Ryan A Maddox Wen-Quan Zou Laura Cracco Ignazio Cali 《BMC neurology》2011,11(1):136
Background
Sporadic fatal insomnia (sFI) and fatal familial insomnia (FFI) are rare human prion diseases. 相似文献10.
Ann Pa Jill S. Craven Xiaotao T. Bi Staffan Melin Shahab Sokhansanj 《The International Journal of Life Cycle Assessment》2012,17(2):220-231
Purpose
Environmental footprints of wood pellets produced in British Columbia (BC) of Canada are to be estimated based on industry surveys and published emission factor data. 相似文献11.
Emily Mulherin Jill Bryan Marijke Beltman Luke O'Grady Eugene Pidgeon Lucie Garon Andrew Lloyd John Bainbridge Helen O'Shea Paul Whyte Séamus Fanning 《BMC veterinary research》2008,4(1):1-8
Background
Results regarding the use of bovine somatotropin for enhancing fertility in dairy cattle are variable. Here, the hypothesis was tested that a single injection of a sustained-release preparation of bovine somatotropin (bST) during the preovulatory period would improve pregnancy success of lactating dairy cows at first service. 相似文献12.
Lutz Herrmann Ulrike Bockau Arno Tiedtke Marcus WW Hartmann Thomas Weide 《BMC biotechnology》2006,6(1):21-11
Background
Dihydrofolate reductase (DHFR) and thymidylate synthase (TS) are crucial enzymes in DNA synthesis. In alveolata both enzymes are expressed as one bifunctional enzyme. 相似文献13.
Jane Wang King-Jen Chang Chin-Yu Chen Kuo-Liong Chien Yuh-Show Tsai Yuh-Ming Wu Yu-Chuan Teng Tiffany Ting-Fang Shih 《Biomedical engineering online》2010,9(1):3
Background
The study was conducted to investigate the diagnostic performance of infrared (IR) imaging of the breast using an interpretive model derived from a scoring system. 相似文献14.
Sylvie Grandemange Sophie Schaller Shigeru Yamano Stanislas Du Manoir George V Shpakovski Marie-Geneviève Mattei Claude Kedinger Marc Vigneron 《BMC molecular biology》2001,2(1):14
Background
The sequences encoding the yeast RNA polymerase II (RPB) subunits are single copy genes. 相似文献15.
Yasuyuki Kobayashi Jon T Giles Masaharu Hirano Isamu Yokoe Yasuo Nakajima Joan M Bathon Joao AC Lima Hitomi Kobayashi 《Arthritis research & therapy》2010,12(5):R171
Introduction
Rheumatoid arthritis (RA) is a multi-organ inflammatory disorder associated with high cardiovascular morbidity and mortality. We sought to assess cardiac involvement using a comprehensive cardiac magnetic resonance imaging (cMRI) approach and to determine its association with disease characteristics in RA patients without symptomatic cardiac disease. 相似文献16.
Background
A method for inhibiting the expression of particular genes using external guide sequences (EGSs) has been developed in bacteria, mammalian cells and maize cells. 相似文献17.
Winfried Häuser Petra Klose Jost Langhorst Babak Moradi Mario Steinbach Marcus Schiltenwolf Angela Busch 《Arthritis research & therapy》2010,12(3):R79
Introduction
The efficacy and the optimal type and volume of aerobic exercise (AE) in fibromyalgia syndrome (FMS) are not established. We therefore assessed the efficacy of different types and volumes of AE in FMS. 相似文献18.
Introduction
BRAF (v raf murine sarcoma viral oncogene homologue B1) is a serine-threonine kinase involved in the mitogen-activated protein kinase (MAPK) signalling pathway, known to be implicated in the production of pro-inflammatory cytokines. 相似文献19.
Marcelo H Ratto Wilfredo Huanca Gregg P Adams 《Reproductive biology and endocrinology : RB&E》2010,8(1):44
Background
Previously, we documented the presence of ovulation-inducing factor (OIF) in the seminal plasma of llamas and alpacas. The purpose of the study was to define the biochemical characteristics of the molecule(s) in seminal plasma responsible for inducing ovulation. 相似文献20.