共查询到20条相似文献,搜索用时 31 毫秒
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Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development 总被引:9,自引:0,他引:9
Takeuchi JK Mileikovskaia M Koshiba-Takeuchi K Heidt AB Mori AD Arruda EP Gertsenstein M Georges R Davidson L Mo R Hui CC Henkelman RM Nemer M Black BL Nagy A Bruneau BG 《Development (Cambridge, England)》2005,132(10):2463-2474
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Tbx5 is essential for heart development 总被引:11,自引:0,他引:11
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Davidson B 《Seminars in cell & developmental biology》2007,18(1):16-26
The primitive chordate Ciona intestinalis has emerged as a significant model system for the study of heart development. The Ciona embryo employs a conserved heart gene network in the context of extremely low cell numbers and reduced genetic redundancy. Here, I review recent studies on the molecular genetics of Ciona cardiogenesis as well as classic work on heart anatomy and physiology. I also discuss the potential of employing Ciona to decipher a comprehensive chordate gene network and to determine how this network controls heart morphogenesis. 相似文献
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Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart 总被引:8,自引:0,他引:8
Stennard FA Costa MW Elliott DA Rankin S Haast SJ Lai D McDonald LP Niederreither K Dolle P Bruneau BG Zorn AM Harvey RP 《Developmental biology》2003,262(2):206-224
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Yang L Cai CL Lin L Qyang Y Chung C Monteiro RM Mummery CL Fishman GI Cogen A Evans S 《Development (Cambridge, England)》2006,133(8):1575-1585