共查询到20条相似文献，搜索用时 31 毫秒
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The effect of oxytocin on collagen synthesis in the pregnant human cervix and lower uterine segment was studied in incubation experiments by measuring the incorporation of 3H-proline. Oxytocin had a concentration related inhibitory effect on the labelling with 3H-proline. Vasopressin in the corresponding concentrations had only a weak effect on the incorporation of 3H-proline. Addition of indomethacin did not influence the response to oxytocin indicating that the effect was probably not mediated by prostaglandins. These results suggest that oxytocin under in vitro experimental conditions influences cervical connective tissue metabolism which is in contrast to current clinical experience. 相似文献
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G Asboe-Hansen 《Federation proceedings》1966,25(3):1136-1140
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M J Walport 《BMJ (Clinical research ed.)》1987,294(6569):392-393
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LOEVEN WA 《Acta anatomica》1955,24(3-4):217-244
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In spite of the extensive literature, little is known of the diagnostic value of the enzymes of connective tissue metabolism. This review summarizes the available information and assesses the significance of enzyme measurements for the diagnosis of hereditary and nonhereditary connective tissue diseases, with emphasis being given to the roles of abnormal activities of collagenases and lysosomal glycosidases in the detection of fibrotic processes. 相似文献