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1.
Unstressed living bone exhibits bioelectric potential differences along its surface. This electrogenic behavior has been characterized by a V=f(l) curve which is linear up to a certain limit. To better understand the origin and meaning of these potentials and to better describe this electrogenic behavior an electrochemical generator (a silver-oxide cell) was included, instead of bone, into the same measurement situation used to describe the V=f(I) curve of the rabbit tibia. The V=f(I) curve of the cell was graphically compared with the V=f(I) curve of the living unstressed rabbit tibia: the two curves were superimposable. This suggests that an electrochemical mechanism may be at the origin of the bioelectric potentials in unstressed living bone.  相似文献   

2.
The use of biomass cook stoves is widespread in the domestic sector of developing countries, but the stoves are not efficient. To advance the versatility of the cook stove, we investigated the feasibility of adding a commercial thermoelectric (TE) module made of bismuth-telluride based materials to the stove's side wall, thereby creating a thermoelectric generator system that utilizes a proportion of the stove's waste heat. The system, a biomass cook stove thermoelectric generator (BITE), consists of a commercial TE module (Taihuaxing model TEP1-1264-3.4), a metal sheet wall which acts as one side of the stove's structure and serves as the hot side of the TE module, and a rectangular fin heat sink at the cold side of the TE module. An experimental set-up was built to evaluate the conversion efficiency at various temperature ranges. The experimental set-up revealed that the electrical power output and the conversion efficiency depended on the temperature difference between the cold and hot sides of the TE module. At a temperature difference of approximately 150 degrees C, the unit achieved a power output of 2.4W. The conversion efficiency of 3.2% was enough to drive a low power incandescent light bulb or a small portable radio. A theoretical model approximated the power output at low temperature ranges. An economic analysis indicated that the payback period tends to be very short when compared with the cost of the same power supplied by batteries. Therefore, the generator design formulated here could be used in the domestic sector. The system is not intended to compete with primary power sources but serves adequately as an emergency or backup source of power.  相似文献   

3.
This paper has described techniques permitting the first simultaneous recordings of ‘stress-generated’ electrical potentials from bone, together with mechanical strain, during ambulation in a living animal. Results of further studies should advance understanding of the mechanisms underlying Wolffs Law, and assist in design of devices intended to stimulate bone formation by application of electrical energy.  相似文献   

4.
A theoretical mechanism is described allowing biomembranes to convert heat into electrical energy during temperature cycling (thermosynthesis). Necessary conditions for thermosynthesis are a temperature dependent electrical capacity and a conductivity as low as that of artificial lipid bilayers. Temperature cycling, and consequently thermosynthesis, can take place in leaves during cyclic transpiration and in organisms in natural waters that are carried along by convection currents. Electrogenic ATPases can convert the electrical energy gained by thermosynthesis into ATP if their activity and stoichiometry are properly regulated. The power of thermosynthesis is discussed and its possible value compared with the power of respiration. Environments where thermosynthesis may occur are listed. Thermosynthesis is a plausible energy source for the first living organisms.  相似文献   

5.
In this study, we show the use of direct external electrical stimulation of a jellyfish luminescent calcium-activated protein, aequorin, expressed in a transgenic yeast strain. Yeast cultures were electrically stimulated through two electrodes coupled to a standard power generator. Even low (1.5 V) electric pulses triggered a rapid light peak and serial light pulses were obtained after electric pulses were applied periodically, suggesting that the system is re-enacted after a short refraction time. These results open up a new scenario, in the very interphase between synthetic biology and cybernetics, in which complex cellular behavior might be subjected to electrical control.  相似文献   

6.
The fast growth of smart electronics requires novel solutions to power them sustainably. Portable power sources capable of harvesting biomechanical energy are a promising modern approach to reduce battery dependency. Herein, a novel elastic impact‐based nonresonant hybridized generator (EINR‐HG) is reported to effectively harvest biomechanical energy from diverse human activities outdoors. Through the rational integration of a nonlinear electromagnetic generator with two contact‐mode triboelectric nanogenerators, the proposed EINR‐HG generates hybrid electrical output simultaneously under the same mechanical excitations. By introducing a flux‐concentrator with a nanowire‐nanofiber surface modification, significant improvement in the energy harvesting efficiency of the EINR‐HG is achieved. After optimizing using simulations and vibration tests, the as‐fabricated EINR‐HG delivers an outstanding normalized power density of 3.13 mW cm?3 g?2 across a matching resistance of 1.5 kΩ at 6 Hz under 1 g acceleration. Under human motion testing, the EINR‐HG generates an optimal output power of 131.4 mW with horizontal handshaking. With a customized power management circuit, the EINR‐HG serves as a universal power source that successfully drives commercial smart electronics, including smart bands and smartphones. This work shows the massive potential of biomechanical energy‐driven hybridized generators for powering personal electronics and portable healthcare monitoring devices.  相似文献   

7.
Advanced thermoelectric technologies can drastically improve energy efficiencies of industrial infrastructures, solar cells, automobiles, aircrafts, etc. When a thermoelectric device is used as a solid‐state heat pump and/or as a power generator, its efficiency depends pivotally on three fundamental transport properties of materials, namely, the thermal conductivity, electrical conductivity, and thermopower. The development of advanced thermoelectric materials is very challenging because these transport properties are interrelated. This paper reviews the physical mechanisms that have led to recent material advances. Progresses in both inorganic and organic materials are summarized. While the majority of the contemporary effort has been focused on lowering the lattice thermal conductivity, the latest development in nanocomposites suggests that properly engineered interfaces are crucial for realizing the energy filtering effect and improving the power factor. We expect that the nanocomposite approach could be the focus of future materials breakthroughs.  相似文献   

8.
Electromagnetic fields (EMFs) played a role in the initiation of living systems, as well as subsequent evolution. The more recent literature on electrochemistry is documented, as well as magnetism. The large numbers of reports on interaction with living systems and the consequences are presented. An important aspect is involvement with cell signaling and resultant effects in which numerous signaling pathways participate. Much research has been devoted to the influence of man-made EMFs, e.g., from cell phones and electrical lines, on human health. The degree of seriousness is unresolved at present. The relationship of EMFs to reactive oxygen species (ROS) and oxidative stress (OS) is discussed. There is evidence that indicates a relationship involving EMFs, ROS, and OS with toxic effects. Various articles deal with the beneficial aspects of antioxidants (AOs) in countering the harmful influence from ROS-OS associated with EMFs. EMFs are useful in medicine, as indicated by healing bone fractures. Beneficial effects are recorded from electrical treatment of patients with Parkinson’s disease, depression, and cancer.  相似文献   

9.
A new pulsed radio frequency electric field pattern evolved from bone studies was adopted to accelerate fracture healing in rats. The output of a specially designed signal generator was ca-pacitatively coupled to the fracture site using a pair of stainless steel electrodes. In a series of experiments performed on rats, fractures were induced in the femoral shafts and electrical stimulations were applied to one leg. Bone mass formed in the gap was estimated by measurement of the cortical thickness and by ultrasonic attenuation. We found that the stimulated side showed greater bone mass than the contralateral control. We suggest that. this device offers a simple and reliable method of acclerated healing, immediately after fracture.  相似文献   

10.
The velocity of ultrasound waves through bone has been used widely as a non-invasive method for assessing bone quality. Accurate measurement of velocity depends on accurate assessment of the distance travelled by the sound wave. It has been argued that the sonic pathway is deflected around the marrow cavity and so does not follow a straight line through the bone; therefore, correction factors have been developed to account for the extra distance travelled. This hypothesis was examined in vitro using sections from the equine third metacarpal bone. Two 1 MHz transducers used with the transmitting transducer energized by a 600 V electrical spike generator produced a 0.1 μs pulse width and the received signal was recorded on a delayed time-base oscilloscope, from which the velocity was calculated. Two distinct peaks were apparent in the received signal, corresponding to a direct cortical transmission wave and a direct medullary transmission wave. This observation was confirmed quantitatively using models of the third metacarpal made from homogeneous materials that allow accurate determination of the transit times of each component of the signal. Perspex was used to mimic cortical bone, with water as the mimic for the contents of the medullary canal; these materials were chosen because they have transmission velocities similar to the materials they were mimicing. The results confirmed that the pathway went straight through the bone with a time lag in the medullary wave due to the slower transmission velocity of the marrow. To ensure that the cortical wave is always received, transducers larger than the medullary width should always be used.  相似文献   

11.
L I Titomir 《Biofizika》1975,20(4):693-698
A set of characterisitics of the cardiac electrical generator is described which expresses in an integral form some important properties of the electrical excitation wave, in particular its summary intensity, average spatial localization and distinction from a uniform double layer with planar rim. Relation of the proposed model to the multipole equivalent generator is discussed, and procedures for computing its characteristics are given. Calculation results for these characteristics on the basis of experimentally measured electrical field potentials of isolated dog hearts are presented.  相似文献   

12.
A cross-sectional study was carried out to assess the growth of 780 children of both sexes, aged between 0-12 years, and living at two different areas in Ismailia, Egypt, with approximately similar socioeconomic standards. Based on a designed questionaire, the exposed group was formed of 390 children from the Abu Sultan area. They were chosen from families living within 50 meters nearby high voltage electric power lines. Another 390 children from the El-Sheikh Zayed area were chosen as the control group. Standard anthropometric measurements were carried out for each child. Plain X-ray was done on the hands of 200 randomly selected children from both groups (100 each) to assess their bone maturation. In the exposed group the weight was significantly decreased only at birth, while the circumferences of the head and chest as well as the height were significantly reduced at all studied ages. The radiological study revealed a significant delay in carpal bone ossification of the exposed children. In conclusion: Exposure to low frequency electromagnetic fields emerged from high voltage electric power lines increases the incidence of growth retardation of children. Isolating these power lines in a scientific way in order to shield both the magnetic and electric fields or removing them far away from the inhabitant areas is recommended.  相似文献   

13.
A rapid solvent evaporation method based on the triple point of a processing solvent is presented to prepare carbon nanotube (CNT) foam with a porous structure for thermoelectric (TE) power generators. The rapid solvent evaporation process allows the preparation of CNT foam with various sizes and shapes. The obtained highly porous CNT foam with porosity exceeding 90% exhibits a low thermal conductivity of 0.17 W m?1 K?1 with increased phonon scattering, which is 100 times lower than that of a CNT film with a densely packed network. The aforementioned structural and thermal properties of the CNT foam are advantageous to develop a sufficient temperature gradient between the hot and cold parts to enhance TE output characteristics. To improve the electrical conductivity and Seebeck coefficient further, p‐ and n‐molecular dopants are easily introduced into the CNT foam, and the optimized condition is investigated based on the TE properties. Finally, optimized p‐ and n‐doped CNT foams are used to fabricate a vertical and flexible TE power generator with a combination of series and parallel mixed circuits. The maximum output power and output power per weight of the TE generator reach 1.5 µW and 82 µW g?1, respectively, at a temperature difference of 13.9 K.  相似文献   

14.
In experiments on white rats the generator of excitation was created in the dorsal raphe nucleus by microinjection of tetanus toxin. After formation of the excitation generator electrical activity in this nucleus was changed as the following: the first negative component (N1) was strongly increased, general EP configuration changed and the spontaneous paroxysmal activity became more frequent. The time of the generator formation correlated with the appearance of intense and prolonged analgesia. Naloxone did not reverse the effects of analgesia described.  相似文献   

15.
This paper reports on the first stage in developing microbial fuel cells (MFCs) which can operate underwater by utilizing dissolved oxygen. In this context, the cathodic half-cell is likened to an artificial gill. Such an underwater power generator has obvious potential for autonomous underwater robots. The electrical power from these devices increased proportionately with water flow rate, temperature and salinity. The current output at ambient temperature (null condition) was 32 microA and this increased by 200% (approximately 100 microA) as a result of a corresponding temperature increase (DeltaT) of 52 degrees C. Similarly, the effect of increasing the water flow rate resulted in an increase in the MFC output ranging from 135% to 150%. Furthermore, the same positive effect was recorded when artificial seawater was used instead, in which case the increase in the MFC current output was >100% (from 32 to 65 microA). There was a distinct difference in the MFC performance when operated under low turbulent as opposed to high turbulent flow rates. These findings can be advantageous in the design of underwater autonomous robots.  相似文献   

16.
It has previously been shown that the site of production of the generator potential in Pacinian corpuscles is the receptor membrane of the non-myelinated ending, and the site of initiation of the nerve impulse, the adjacent (first) Ranvier node. Effects of membrane polarization of these sites were studied in the present work. Nerve ending and first Ranvier node were isolated by dissection, electric activity was recorded from, and polarizing currents were passed through them. All observations were done at steady levels of polarization, seconds after onset of current flow. The following results were obtained: The amount of charge transferred through the excited receptor membrane is a function of the electrical gradients across the membrane. The generator potential in response to equal mechanical stimuli increases with resting potential of the receptor membrane. The refractory state of the generator potential is not affected by polarization. The electrical threshold for impulse firing at the first Ranvier node (measured by the minimal amplitude of generator potential which elicits a nodal impulse) is nearly minimal at normal resting potential of the node. Both, hyperpolarization and depolarization lead to a rise in nodal threshold. For any level of polarization of nodal and receptor membrane, the threshold for production of impulses by adequate (mechanical) stimulation appears determined by the generator potential-stimulus strength relation and by the electrical threshold of the node.  相似文献   

17.
Electro-mechanical behavior of wet bone--Part I: Theory   总被引:1,自引:0,他引:1  
The remodeling properties of bones due to various stimuli have been of substantial interest to the scientists. Examination of electro-mechanical properties of bone and their relation to remodeling and osteogenesis have been investigated mainly by experimental means. In this study, by using continuum physics, it is shown that the remodeling of bones can be formulated theoretically in terms of electrical and mechanical effects. The interactions among the constituents of bone (bone matrix, bone salts, electrolytes and hydrogen ions) and effects of various stimuli (mechanical, electrical and chemical) on the remodeling mechanism of bone tissue are interpreted with this model. Moreover, the stimulation of osteogenesis by electrical means is predicted.  相似文献   

18.
A possibility of formation of a generator of pathologically enhanced excitation in the system of the vestibular nuclei of the medulla oblongata by disturbance of their inhibitory processes (resulting in development of contralateral rotatory motions in animals) was shown. Experiments with electrical stimulation of the lateral vestibular nucleus and its coagulation showed the system of the vestibular neurons organizing the synchronous message by the vestibulo-spinal pathways to underlie the generator of the pathologically enhanced excitation. It was concluded that the generator of the pathologically enhanced excitation formed in the lateral vestibular nucleus as a result of disturbed inhibition underlied the hyperactive determinative dispatch station causing the syndrome of vestibulopathy  相似文献   

19.
When recording from the tip of insect taste hairs, responses to chemical stimulation may be influenced by electrical currents, such as the preamplifier's input bias current. The effect of electrical currents on firing frequency of the salt receptor cell to KCl and NaCl stimulation was determined in labellar ‘aboral’ and ‘adoral’ taste hairs of the blowfly Calliphora vicina. Negative currents always decreased spike frequency, whereas positive currents either increased it, or did not change it significantly. Spike frequency changed less than 1% per 5 × 10?11 A.A consistent picture of the electrophysiology of blowfly taste hairs is given. It includes a distal pore, present in the dendrite-free lumen of the hair. It abandons the concept of a generator current that transmits excitation from the distal, chemoreceptive part of the taste cell dendrite to the action potential generator in or near the taste cell body. The experimental results are interpreted on the basis of this picture. It is concluded that the ‘electrophoretic effect’ of the electrical current is very small. Thus, the measured effect should mainly be due to a ‘direct effect’ of electrical current on electrically excitable structures in the salt receptor cell, particularly in its dendrite.  相似文献   

20.
An original set-up replacing generator of sound frequencies is suggested. This set-up connected with AC current of 50 Hz frequency can be used as a power source to the electromagnetic vibrator with the frequency of the mechanical resonance of 200 Hz.  相似文献   

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