臭灵丹中四个新的倍半萜酸

从云南省芒市产臭灵丹［Ｌａｇｇｅｒａｐｔｅｒｏｄｎｔａ（ＤＣ．）Ｂｅｎｔｈ］中,分离得以４个新的桉烷型倍半萜酸,结构鉴定为５,１２－二烯－桉烷－１３－酸（１）;１β－式－５,１２－二烯－桉烷－１３－酸（２）;３β－羟基－５,１２－二烯－桉烷－１３－酸（３）。     

臭灵丹四醇的结构

臭灵丹四醇的结构李顺林，丁靖垲（中国科学院昆明植物研究所植物化学开放研究室验室，昆明６５０２０４）关键词四棱峰，臭灵丹，倍半萜，臭灵丹四醇ＴＨＥＳＴＲＵＣＴＵＲＥＯＦＰＴＥＲＯＤＯＮＴＥＴＲＡＡＯＬＦＲＯＭＬＡＧＧＥＲＡＰＴＥＲＯＤＯＮＴＡ￥ＬＩＳｈ...     

朝鲜蓟叶中一个新的倍半萜内酯

从朝鲜蓟（Cynarascolyrnus）叶中分离得到2个倍半萜内酯,其中一个是新化合物,通过波谱学方法确定其结构为3β,8α,11α,13-四羟基-10（14）-愈创木烯-1α,4β,5α,6β氢-6α,12-内酯（1）。     

臭灵丹中的黄酮醇成分

臭灵丹中的黄酮醇成分李顺林,丁靖垲（中国科学院昆明植物研究所植物化学开放研究室验室,昆明６５０２０４）关键词四棱峰属,臭灵丹,黄酮醇ＴＨＥＦＬＡＶＯＮＯＬＳＦＲＯＭＬＡＧＧＥＲＡＰＴＥＲＯＤＯＮＴＡ￥ＬＩＳｈｕｎ－Ｌｉｎ;ＤＩＮＧＪｉｎｇ－Ｋａｉ（Ｌ...     

云南含笑中的新倍半萜醇

从云南含笑ＭｉｃｈｅｌｉａｙｕｎｎａｎｅｎｓｉｓＦｒ．ｅｘＦｉｎ．ｅｔＧａｇｎ中分离得到１个新的倍半萜醇,命名为１２,１３－ｄｉ－ａｃｅｔｏｘｙｌ－１．４．６１１－ｅｕｄｅｓｍａｎｅｔｅｔｏｌ,以及３个已知的倍半萜内酯１β－ｈｙｄｒｏｘｙａｒｂｕｓｃｕｌｉｎＡ２,ｒｅｙｎｏｓｉｎ３,ｐａｒｔｈｅｎｏｌｉｄｅ４和３个木脂素３－（α,４－ｄｉｈｙｄｒｏｘｙ－３－ｍｅｔｈｏｘｙｂｅｎｚｙｌ）－４－（４－     

臭灵丹中五个新的桉烷类衍生物

臭灵丹中五个新的桉烷类衍生物赵昱岳建民林中文王德祖丁靖垲孙汉董（中国科学院昆明植物研究所植物化学开放实验室,昆明６５０２０４）ＦＩＶＥＮＥＷＥＵＤＥＳＭＡＮＥＤＥＲＩＶＡＴＩＶＥＳＦＲＯＭＬＡＧＧＥＲＡＰＴＥＲＯＤＯＮＴＡＺｈａｏＹｕ,ＹｕｅＪ...     

乌药中3个新的倍半萜

研究乌药的化学成分。采用硅胶、ODS、Sephadex LH-20、制备液相等多种色谱分离技术进行分离纯化,通过波谱数据分析进行结构鉴定。从乌药90%乙醇提取物中分离得到4个倍半萜,分别鉴定为linderaggredin B1(1)、乌药酮酸A(2)、乌药酮酸B(3)、chlorahupetolide K(4),其中化合物1～3为新化合物,化合物4为首次从樟科中分离得到。     

山楝枝叶中两个新的倍半萜

本文报道了对山楝Aphanamixis polystachya枝叶的化学成分进行研究.采用硅胶柱色谱、Sephadex LH-20、RP-C18、HPLC等色谱分离手段,从其95％乙醇提取物中分离得到9个化合物,通过波谱方法进行鉴定为polystachyadione A(1)、polystachyadione B (2...     

甘松醛：一个新的倍半萜过氧化物

从甘松(Nardostachys chinensis.Batal)的根中分离到了一个新的倍半萜过氧化物——甘松醛(Nardosaldehyde),并通过J-分解谱等二维核磁共振技术鉴定了其结构。     

蒿属和各里光属植物中桉烷型倍半萜的光谱特征

本文就菊科中的两个大属蒿属和千里光属植物中一类典型倍半萜成分－桉烷型倍半萜的光谱特征进行综述。     

FIVE NEW EUDESMANE DERIVATIVES FROM LAGGERA PTERODONTA

Three eudesmanoic acids (1~ 3) and two eudesmanoic acid glucosides (4-5) were isolated from the n-BuOH extract of the title plant.     

Chemical Composition and Antimicrobial Activities of Essential Oils of Laggera pterodonta Collected in Four Different Locations in Yunnan,China*

Essential oils obtained by hydrodistillation from leaves of Laggera pterodonta collected from four different locations (Kunming, Lijiang, Puer and Xinping) in Yunnan, China, were analyzed using GC MS and GC FID. The number of compounds identified in each sample was 39, 37, 33 and 44, respectively, representing 9332% (Kunming), 8057% (Lijiang), 9224% (Puer) and 9385% (Xinping) of total essential oils. Chemical compositions of essential oils differed between sample locations: thus, those from Kunming were rich in benzenoid compounds (3806%) while those from Lijiang and Puer were largely dominated by sesquiterpenes (1989% and 4465% respectively) and sesquiterpenes oxide (4085% and 3511%, respectively), and those from Xinping contained a high proportion of monoterpene hydrocarbons and sesquiterpene hydrocarbons (4223% and 3325% respectively) (7548%). The results of tests on the antimicrobial activities of essential oils indicated that chemical composition was affected by environmental variation causing differences in sensitivity to microbes among samples.     

云南植物三新种

<正> 马鞭草科 VERBENACEAE 紫珠属 CalliCarpa 细花紫珠 (江城紫珠) 新种 图1 Callicarpa minutiflora Y. Y. Qian, sp. nov. C. jiangchengensis Y. Y. Qian, ined. Species affinis C. acutifoliae H. T. Chang, sed foliis ellipticis, utrinque stellatopilosis, nervis lateralibus utrinseeus 7—9, cymis 4—6 cm latis, 5—7-     

云南不同产地臭灵丹精油化学成分及抗菌活性

采用水蒸气蒸馏的方法,对采自云南4个不同地区（昆明,丽江,普洱,新平）的臭灵丹叶子进行挥发油提取,并利用GC MS和GC FID气相色谱联用技术分析其化学组成,分别从中鉴定出39、37、33、44个化合物。鉴定的化合物各占挥发油总量的9332% (昆明)、8057% (丽江)、9224% (普洱)和9385% (新平)。研究结果表明,采自这四个地区植物样品提取所得挥发油化学组成不尽相同：昆明产臭灵丹挥发油富含芳香族化合物(3806%);而从丽江和普洱样品中获得的挥发油化学成分以倍半萜（分别为1989%和4465%）和氧化倍半萜（分别为4085%和3511%）为主;非氧化单萜和非氧化倍半萜化合物（分别为4223%和3325%）则是新平产臭灵丹挥发油的主要化合物类型。同时,对这些不同产地的臭灵丹挥发油也进行了抗菌活性测试。从以上实验研究结果推测环境差异是影响臭灵丹挥发油化学组成差异的重要因素,而不同的化学组成可能是导致4种样品抗菌敏感程度不同的原因。     

花锚的三种新(口山)酮甙

从抗肝炎植物药花锚中分得了三种新天然产(口山)酮双糖甙。经化学反应和光谱分析,化合物Ⅰ和Ⅱ分别被鉴定为1-O-[β-D-木吡喃糖-(1-6)-β-D-葡萄吡喃糖]-2,3,5,7-四甲氧基(口山)酮和1-O-[β-D-木吡喃糖-(1-6)-β-D-葡萄吡喃糖]-2,3,5-三甲氧基(口山)酮。经药理实验证明,该两成分为该植物抗肝炎的主要水溶性活性成分。化合物Ⅲ的结构初步被鉴定为1-0-[β-D-木吡喃糖-(1-6)-β-D-葡萄吡喃糖]-2,3,4,5-四甲氧基(口山)酮。     

瓦草中三个新环肽

从云南民间中草药瓦草（Ｓｉｌｅｎｅｓｚｅｃｈｕｅｎｓｉｓ）的根中分离鉴定了３个新的环肽,分别命名为瓦草环肽Ａ,Ｂ,Ｃ（ｓｉｌｅｎｉｎｓＡ,Ｂ,Ｃ）用光谱和化学方法确定它们均为环八肽,其结构分别为：ｓｉｌｅｎｉａＡ－ｃｙｃｌｏ－（Ｐｒｏ－Ｌｅｕ－Ｓｅｒ－Ｐｈｅ－Ｐｒｏ－Ｔｙｒ－Ｌｅｕ－Ｖａｌ）,ｓｉｌｅｎｉｎＢ－－ｃｙｃｌｏ－（Ｐｈｅ－Ｌｅｕ－Ａｌａ－Ｐｒｏ－Ｌｅｕ－Ｐｒｏ－Ｐｈｅ－Ｐｒｏ）,ｓｉｌ     

臭灵丹水提取物的急性毒性及镇痛作用的实验研究

采用上下移动法,醋酸扭体法、热板法、福尔马林致痛试验对臭灵丹水提取物的急性毒性及镇痛作用进行了研究。结果显示：臭灵丹水提取物LD50（腹腔注射）为1．19g／kg;臭灵丹水提取物明显抑制醋酸所致的小鼠扭体数,显著减少福尔马林致痛试验后期小鼠舔足行为;而对热板法所致疼痛无明显作用。表明臭灵丹水提取物具有一定的外周镇痛作用。     

Fragrant Volatile Sesquiterpenoids Isolated from the Essential Oil of Laggera pterodonta by Using Olfactory‐Guided Fractionation

Chemical composition of the essential oil from Laggera pterodonta (Compositae) was inverstigated. GC/MS Analyses led to the identification of 68 components, representing more than 96% of the total oil. By focusing on the woody note fraction of the essential oil, one new bisabolane‐type sesquiterpenoid, bisabola‐2,7(14),11‐trien‐10‐ol ( 1 ), together with ten known compounds, bisabolol oxide B ( 2 ), ylangenol ( 3 ), copaborneol ( 4 ), guai‐11‐en‐10‐ol ( 5 ), spathulenol ( 6 ), aromadendran‐10‐ol ( 7 ), caryophyllenol ( 8 ), 5α,7α‐eudesm‐11(13)‐en‐4α‐ol ( 9 ), γ‐costic acid ( 10 ), and eudesma‐4(15),11(13)‐diene‐12,5β‐olide ( 11 ), were isolated by using olfactory‐guided fractionation. The structures of the eleven compounds were determined by NMR and MS analyses. All the volatile compounds reported here were isolated for the first time from this plant. On the basis of preliminary odor assessment, the odor of the woody‐note fractions of the essential oil was assumed to be due to these isolated sesquiterpenoids.