‘Have you got the Britísh?’: narratives of migration and settlement among Albanian-origin immigrants in London

Studies on migration and integration in Britain have noted the paucity of research on ‘new’ migrants, especially ‘illegal’ migrants and asylum seekers. This paper focuses on one understudied group – Albanian immigrants and their children – and looks at their migration and settlement, based on sixty interviews conducted in two phases either side of a 2003 mini-amnesty that gave many indefinite leave to remain. This regularization is the fulcrum around which our analytical narrative is built. Focusing on the interaction of migrants' agency with host-country structure, the paper shows that an unsettled asylum policy and delays in implementation have had deleterious effects on migrants' integration and sense of belonging, even after citizenship acquisition. As they search for a social and ethnic positioning within a multi-ethnic host society, the eventual realization of Albanians' migration project is accompanied by culture shock, intergenerational difference and ambivalence towards integration.     

Biobanking and public health: is a human rights approach the tie that binds?

Ethical principles guiding public health and genomic medicine are often at odds: whereas public health practice adopts collectivist principles that emphasize population-based benefits, recent advances in genomic and personalized medicine are grounded in an individualist ethic that privileges informed consent, and the balancing of individual risk and benefit. Indeed, the attraction of personalized medicine is the promise it holds out to help individuals get the “right medicine for the right problem at the right time.” Research biobanks are an effective tool in the genomic medicine toolbox. Biobanking in public health presents a unique case study to unpack some of these issues in more detail. For example, there is a long history of using banked tissue obtained under clinical diagnostic conditions for later public health uses. But despite the collectivist approach of public health, the principles applied to the ethical challenges of biobanking (e.g. informed consent, autonomy, privacy) remain individualist. We demonstrate the value of using human rights as a public health ethics framework to address this tension in biobanking by applying it to two illustrative cases.     

Amelioration of human osteoarthritis symptoms with topical ‘biotherapeutics’: a phase I human trial

Osteoarthritis (OA) treatments presently rely on analgesics, which manage pain but fail to restore imbalances between catabolic and anabolic processes that underlie OA pathogenesis. Recently, biologic (biotherapeutic) drugs, which alter the activity of catabolic agents such as nitric oxide and inflammatory cytokines in ways, allowing tissue regeneration, were evaluated for efficacy in OA treatment. These studies failed to demonstrate dramatic abatement of OA symptoms by these drugs, but suggested strategies by which biologic agents might be used to treat OA. The present review summarizes current understanding of OA pathogenesis and evolving treatments. Preliminary evaluations of a novel biotherapeutic strategy are presented here. Twenty OA patients receiving sour topical cherry seed extract (SCE), an inducer of heme oxygenase-1 (HO-1), a major physiological protectant against oxidative stress exhibited significantly decreased joint pain and activation of CD4+ T cells expressing inflammatory cytokines (p < 0.05), significantly decreased peripheral blood C-reactive protein (CRP), and increased leukocyte HO-1 (p < 0.05) in comparison with ten placebo-treated patients. SCE inhibits joint-damaging inflammatory mediator production. This agent therefore meets the main criterion for classification as a “biotherapeutic,” or “biologic” agent. The negligible toxicity and low cost of such materials make them promising contributors to OA treatment, sustainable within resource limitations of a wide range of patients.     

‘Structure liberates?’: mixing for mobility and the cultural transformation of ‘urban children’ in a London academy

Abstract

This paper explores how the creation of a socially and ethnically mixed student body relates to mobility within the context of Beaumont Academy. This authoritarian school opened in 2004 under the ethos ‘structure liberates’. Based in a predominantly deprived, ethnic minority area of London, Beaumont seeks to culturally transform its students. With its outstanding GCSE results, the school has been championed as a blueprint for reform, yet the cultural implications underlying this approach remain unexamined. The ethos pathologizes the surrounding area while essentializing itself as an ‘oasis in the desert’ liberating students through discipline. The paper explores how mobility is embodied by students and the alterations or eliminations necessary to achieve it. These alterations produce raced and classed positions and bring them into focus, highlighting who needs to ‘adjust’ themselves to accrue value. Uncritical celebrations of mixed-ness conceal structural inequalities lingering beneath the rhetoric of happy multiculturalism and aspirational citizenship. These inequalities are exacerbated by a marketized education system.     

‘I Know that I Do Have HIV but Nobody Saw Me’: Oral HIV Self-Testing in an Informal Settlement in South Africa

Reaching universal HIV-status awareness is crucial to ensure all HIV-infected patients access antiretroviral treatment (ART) and achieve virological suppression. Opportunities for HIV testing could be enhanced by offering self-testing in populations that fear stigma and discrimination when accessing conventional HIV Counselling and Testing (HCT) in health care facilities. This qualitative research aims to examine the feasibility and acceptability of unsupervised oral self-testing for home use in an informal settlement of South Africa. Eleven in-depth interviews, two couple interviews, and two focus group discussions were conducted with seven healthcare workers and thirteen community members. Thematic analysis was done concurrently with data collection. Acceptability to offer home self-testing was demonstrated in this research. Home self-testing might help this population overcome barriers to accepting HCT; this was particularly expressed in the male and youth groups. Nevertheless, pilot interventions must provide evidence of potential harm related to home self-testing, intensify efforts to offer quality counselling, and ensure linkage to HIV/ART-care following a positive self-test result.     

Saprotrophic fungal mycorrhizal symbionts in achlorophyllous orchids: Finding treasures among the ‘molecular scraps’?

Mycoheterotrophic plants are achlorophyllous plants that obtain carbon from their mycorrhizal fungi. They are usually considered to associate with fungi that are (1) specific of each mycoheterotrophic species and (2) mycorrhizal on surrounding green plants, which are the ultimate carbon source of the entire system. Here we review recent works revealing that some mycoheterotrophic plants are not fungal-specific, and that some mycoheterotrophic orchids associate with saprophytic fungi. A re-examination of earlier data suggests that lower specificity may be less rare than supposed in mycoheterotrophic plants. Association between mycoheterotrophic orchids and saprophytic fungi arose several times in the evolution of the two partners. We speculate that this indirectly illustrates why transition from saprotrophy to mycorrhizal status is common in fungal evolution. Moreover, some unexpected fungi occasionally encountered in plant roots should not be discounted as ‘molecular scraps’, since these facultatively biotrophic encounters may evolve into mycorrhizal symbionts in some other plants.Key words: endophytic fungi, evolution of mycorrhizae, mycoheterophy, mycorrhizae, saprophytic fungi, specificityConsiderable advances were recently made in the ecology of achlorophyllous, heterotrophic plants that obtain carbon from their mycorrhizal fungi (Fig. 1). Most plants have contact with soil through mycorrhizal symbioses, in which roots associate with a suitable fungal partner. Fungi utilize soil mineral nutrients, and while sharing them with host plants, they generally receive carbon as a reward. In contrast, some achlorophyllous plants living in the shaded forest understorey have reversed the process. They receive carbon from their mycorrhizal fungi exclusively, hence the designation ‘mycoheterotrophic’ (MH) plants.¹ Mycoheterotrophy has appeared several times during the evolution of land plants, and more than 20 times among orchids that encompass half of all MH species.² In the last decade, the development of molecular tools has enabled researchers to identify many fungal symbionts, which are often uncultivable. The fungi occurring in the densely colonized roots of MH species often produce a stronger PCR signal than any fungal contaminant, making molecular tools very effective for this field of study.Open in a separate windowFigure 1Wullschlaegelia aphylla, a mycoheterotrophic orchid unspecifically associated with saprotrophic Mycena and Gymnopus species. (A) Whole plant at flowering time, with reduced, tuberoid root system at that period. (B) Section of mycorrhizal root showing intracellular hyphal pelotons at early stage (p), or late stage (undergoing lysis, lp); among orchids, the colonization of dead cortical cell (cc) is a unique feature to some saprotrophic fungi (picture by A. Faccio, University of Torino).     

Beyond reified categories: multidimensional identifications among ‘black’ and ‘Indian’ groups in Columbia and Mexico

Analyses of multicultural state-dictated social categories are often governed by those same categories, even while they deconstruct them. Nonetheless, these categories are often used in public spheres such as national imaginary or ethno-political activism. Taking a different point of departure, that of representations rather than the categories themselves, the aim of our paper is to understand the modes of classification that are relevant among four populations in Colombia and Mexico who would, a priori, be categorized as ‘black’ or ‘Indian’. The daily reality of these groups indicates other possible internal, sometimes even intersecting, kinds of categorizations, which, far from naturalizing the ‘Indian’ and ‘black’ categories, in fact reveal place-based social identifications. These identifications seem closer to the everyday lives and practices of the people in question, and underscore the local conceptions of their presence and agency in a given spot.     

‘It's not how it was’: the Chilean diaspora's changing landscape of belonging

Abstract

The increasingly diverse character of London's multicultural landscape has shaped how migrants interact with(in) the different spaces of the city. This process entails both settled and incoming migrants' participation in place-making; a mutual imbrication that might promote the long-settled migrants' evocation of a lost terrain. This article unpacks that process by looking at the Latin American social football scene of South London, specifically a space known as la cancha (the pitch). This was founded by Chilean political refugees during the 1970s and it has incorporated Latin American ‘economic’ migrants and ‘local’ Britons through time. Starting from the evocation of a lost ‘golden age’ of la cancha, the paper unpacks this space's contested, complex and changing nature. It presents diaspora space, community and belonging as lived processes. Through this depiction, the assumptions of homogeneous and isolated migrant communities are challenged, as are the diaspora's nostalgic claims that also emerge from them.     

Between the Great War and the Great Depression: preliminary observations on the ‘missing link’ in the history of human stature in Poland

The paper traces the secular trend in stature in Poland in the interwar period. On the basis of individual measuring cards created by military authorities for Krosno and Sarny districts, the author states that the secular trend in stature that started in the mid-1860s continued between the two world wars with the velocity of at least 0.7 cm per decade, i.e. at a similar rate as in the second half of the 19th century. Although regional differences inside the Second Polish Republic were clearly visible, cohorts born during the Great War were able to make up the lost ground in their teens despite the hardships caused by the Great Depression of the 1930s.     

Procedural understanding in biology: the ‘thinking behind the doing’

Several developments in science education aim to improve pupils' ability to ‘think scientifically’. This paper argues for the explicit teaching of the ideas that pupils need to ‘think about’ to do this; ideas related to the design of investigations and the collection, presentation, analysis, and evaluation of the resulting evidence — ideas which are important both for pupils who continue to study or work with biology and for all pupils to become biologically literate. This paper considers some of the concepts of evidence which are particularly important to biology, and discusses how and why the ideas could be taught.     

The ‘Psychic Surgeon’ and the schizophrenic patient: Crisis in a ‘Medicodrama’

This paper is concerned with a Filipino psychic surgeon confronted by a particularly challenging case of a kind perhaps unprecedented in his practice. The paper describes and analyzes how the practitioner modified his usual clinical performance and adapted his actions to demands of an extremely difficult situation. The case is viewed in wider perspective relative to the significance of performative acts of healing in a pluralistic medical setting.     

Direct selection of mutations in the human mitochondrial tRNAThr gene: reversion of an ‘uncloneable’ phenotype

Several regions of the human mitochondrial genome are refractory to cloning in plasmid and bacteriophage DNA vectors. For example, recovery of recombinant M13 clones containing a 462 basepair MboI-Kpn I restriction fragment that spans nucleotide positions 15591 to 16053 of HeLa cell mitochondrial DNA was as much as 100-fold lower than the recovery of M13 clones containing other regions of the human mitochondrial genome. All of 50 recombinant M13 clones containing this ‘uncloneable’ fragment had one or more changes in nucleotide sequence. Each clone contained at least one alteration in two nucleotide positions within the tRNA^Thr gene that encode portions of the anticodon loop and D-stem of the HeLa mitochondrial tRNA^Thr. These results imply that the HeLa mitochondrial tRNA^Thr gene is responsible for the ‘uncloneable’ phenotype of this region of human mitochondrial (mt) DNA.A total of 61 nucleotide sequence alterations were identified in 50 independent clones containing the HeLa mt tRNA^Thr gene. 56 mutations were single-base substitutions; 5 were deletions. Approximately 80% of the base substitution mutations were A:T → G:C transitions. A preference for A:T → G:C transition mutations also characterizes polymorphic base substitution variants in the mitochondrial DNA of unrelated individuals. This similarity suggests that human mitochondrial DNA sequence variation within and between individuals may have a common origin.     

‘Playing’ at the ethnic boundary: strategic boundary making/unmaking among ethnic Chinese groups in Australia

The sociological literature has constructed a systematic typology of ‘modes’ and ‘means’ of strategic ethnic boundary making/unmaking. Through exploring different strategies, scholars illustrate the processes and contexts of boundary expansion or contraction. Other scholars also distinguish ethnic elements and ‘moral' values attached to certain ethnicities but not to others. This paper acknowledges dynamic boundary making/unmaking and moral aspects of ethnicity, while exploring the different degrees to which national and pan-national identity nest within each other among ethnic Chinese groups, as well as how ethnic boundary becomes a field where people ‘play' in their everyday interactions. Based on participant observations and in-depth interviews from two pan-Chinese worksites in Australia, the paper argues that different interpretations of ethnic identity as well as how different identities (national and pan-national) are nested give people room to ‘play' at the ethnic boundary and result in different outcomes. This paper also shows that people can cross the ethnic boundary (between Taiwanese/Hong Kongese and PRC-Chinese) without expanding/contracting the existing categories or ‘repositioning/transvaluing' their ethnic statuses.     

‘We all eat the same bread’: the roots and limits of cosmopolitan bridging ties developed by Romanians in London

This paper investigates the social ties forged by Romanians in London with migrants of different origins in work and non-work contexts to offer a more nuanced view of ‘bridging’ social ties and related discussions of ‘everyday’ cosmopolitanism. Contrary to the overemphasis on ethnic ties seen as a form of bonding in migration research, the paper shows how Romanians bridge informally with many other migrants based on shared ‘non-native’ status. Alongside non-ethnically marked commonalities, ethnicity emerges as an important ingredient of cosmopolitan socialization, yet without necessarily signalling coexisting ethnic identities, as commonly assumed. Romanians' experiences further show that despite providing significant social and cultural capital, bridging ties with migrants, rather than natives, rarely accrue effective resources for social mobility. The findings suggest the need to disaggregate and qualify current understandings of ‘bridging’ social ties usually depicted in positive terms and uniformly as cross-ethnic relationships, or only linked with the ‘mainstream’ population.