5117例院前急救流行病学特征分析

目的分析柳州市120急救中心下属分中心2010年院前急救患者流行病学特征。方法对柳州市工人医院2010年1月1日～12月31日的院前急救患者的性别、年龄、就诊时间、急诊诊断或主诉、去向等要素进行统计分析。结果2010年我院院前急救患者5117例,男女比为1.46：1,年龄（49．284-22．26）岁,院前急救各月份出诊量最高为12月份,最低为5月份,每日院前急救高峰时间段为8;00～10;00;创伤、神经系统疾病、急诊症状及体征、心血管系统疾病、消化系统疾病、中毒居院前急救疾病谱前6位;30～59岁组男性与其他年龄组比较,更易患创伤和心血管系统疾病。结论（1）加强安全生产、遵守交通法规,降低创伤发生率。（2）加强心脑血管疾病的防治,普及全民急救知识,降低致残率、死亡率。（3）院前急救疾病谱的排序,对指导急诊急救专业人员培训和开展院前急救有重要意义。（4）关注30～59岁男性健康和安全防范教育,减少创伤和心脑血管系统疾病发生。     

留观病房患者的特点与护理人力资源管理

目的了解留观病房患者的特点、疾病谱和入观时间分布规律,做好护理人力资源的管理,保证护理安全。方法对我院2014年1月1日00:00~12月31日00:00收住留观病房的3207例患者的临床资料进行回顾性分析,包括患者的一般资料、收住留观病房的月份、病例数和各时间段入观病例数、疾病谱分布。结果留观病房收住患者以头部损伤、蛇咬伤、呼吸道感染的病例为多,位居前3位;女性多于男性;以3、7月份入观病例数最多,入观时段集中在10:00~14:00、16:00~00:00,其中以10:00~12:00、20:00~22:00为全天入观高峰。结论护理管理者需依据本科室收住留观患者的疾病谱和入观时间分布规律采用弹性的排班原则,合理安排各班次护理人力资源,同时要加强护理业务技术培训,以提高留观病房的护理质量,确保护理安全。     

教学医院急诊日夜就诊病例分析

目的 探讨急诊就诊患者在不同时段的就诊规律,为急诊科管理提供依据。方法 收集门急诊就诊信息系统2009年10月1日—2010年4月30日急诊病例资料。采用多阶段随机抽样方法,共抽取7 634份急诊病例资料。结果 急诊患者中男性多于女性,急诊儿科中位年龄3岁,急诊内科、急诊外科中位年龄32岁。就诊科别以急诊儿科患者占多数。费用类别以自费患者为主。16：00—<00：00时上夜班为就诊高峰时段,在高峰时段,急诊儿科、医疗保险患者增加较明显,但疾病轻重分级以4级及5级轻症病例为主。结论 在就诊高峰时段,要相应调整排班,加强导诊和分诊,可缓解急诊科拥挤现象。学科建设中要加强急诊儿科医师的培养。     

基于就诊流量监测的门诊资源合理分配研究

目的 通过历史流量数据及流量监测系统,对医院门诊流量情况进行分析,为门诊人力资源合理分配提供依据。 方法 应用时间序列数据季节指数分析法对医院历史门诊流量数据按月份、周和每日不同时间段流量进行分析,并对流量监测系统的历史数据进行统计分析。 结果 门诊流量3、5、7、11、12月份较大,1、2月份较少;一周中周一至周三流量较大,周四、周五流量较少;一天中早上8：00～10：00流量较大,呈明显就诊高峰,下午14：00～16：00为就诊低峰。 结论 医院门诊流量在一年的不同月份、每周的不同天次、每日的不同时间段都有不同的变化规律。     

黑河上游天涝池流域草地蒸散发特征及蒸发皿系数研究

选择黑河上游天涝池流域为研究区, 利用Lysimeter 蒸散仪和蒸发皿, 对亚高山草地蒸散发和水面蒸发进行实际观测。结果表明: 在月尺度上, 从4 年的平均看, 6 月最大, 其次是8 月, 7 月最小; 6、7 和8 月的日均蒸散发量都是在2013年最大, 其次为2011 年, 然后是2014 年, 2012 年最小; 2011 和2012 年中, 每月的日均蒸散发量大小顺序为6 月>8 月>7 月;在2013 年中, 8 月份日均蒸散发量最大, 其次为6 月份, 7 月份的日均蒸散发量最小; 但在2014 年中, 7 月份的日均蒸散发量最大, 8 月份和6 月份的相对较小。草地日均蒸散发量成波动状态, 与降雨有一定的关系, 降雨在一天内出现的时间不同, 对蒸散发的影响也不尽相同。日蒸散发量与环境因子之间的相关关系为: 风速>饱和水汽压差>相对湿度>净辐射, R² 分别为0.4174、0.3598、0.3461 和0.3322, 四个气象因子对日蒸散发量都有较大的影响。通过对典型晴天下小时尺度实际蒸散发量与蒸发皿蒸散发量的关系的分析, 将蒸发皿系数分为8:00-14:00 和14:00-20:00 两个时间段和8:00-20:00 整个时间段来计算, 8:00- 14:00 和14:00-20:00 时间段的蒸发皿系数分别大于1 和小于1, 而8:00-20:00 整个时间段蒸发皿系数小于1。     

基于红外相机陷阱技术的阿尔泰山东部北山羊(Capra ibex)的活动节律

2014年5-11月,在我国新疆阿尔泰山东部边界山区放置远红外相机32台,共拍摄到北山羊独立照片3308张。采用日活动差异指数α、昼行性指数β和活动强度指数γ对北山羊的在不同季节活动节律进行分析,结果表明:(1)不同月份北山羊的日活动差异指数α和昼行性指数β均存在极显著差异,且β=0.8313/24,表明在研究区域北山羊属于典型的昼行性动物。(2)春季于7:30-9:30和19:30-21:30、夏季于8:00-10:00和19:00-21:00、秋季于9:00-11:00和18:00-20:00北山羊每日有两个明显的活动高峰。独立多样本检验各季节活动峰型γ值差异显著,说明不同季节北山羊的活动节律存在变化。     

红松阔叶混交林林隙光量子通量密度、气温和空气相对湿度的时空分布格局

以小兴安岭原始红松阔叶混交林林隙为研究对象,通过对林隙内光量子通量密度(PPFD)、气温和空气相对湿度进行连续观测,比较其间的时空分布格局.结果表明：晴天和阴天阔叶红松林林隙的PPFD日最大值均出现在11:00—13:00,晴天林隙内各个时段最大值出现位置不同,日最大值出现在林隙北侧林冠边缘处;而阴天各个时段最大值均处于林隙的中心.林隙内月平均PPFD 为6月最高、9月最低,极差7月最大.林隙内晴天气温的峰值出现在9:00—15:00,而阴天气温峰值在15：00—19：00,均位于林隙中心南8 m.5:00—9:00林隙各点阴天的气温都高于晴天,9:00—19:00则相反.月平均气温为6月最高、9月最低.晴天和阴天空气相对湿度的峰值均出现在5:00—9:00,日最大值在林隙西侧林冠边缘处,且阴天的相对湿度始终大于晴天.月平均相对湿度为7月最高、6月最低.晴天PPFD的异质性大于阴天,而气温和相对湿度的异质性则不明显.生长季内不同月份PPFD、气温和空气相对湿度的最大值所处位置不同.PPFD和气温的月均值在林隙中心及附近变化梯度较大,而相对湿度的月均值则在林隙边缘变化梯度较大.     

南海西沙群岛琛航岛犬牙锥齿鲷生物学特征

2018年5月和9月在南海西沙群岛琛航岛瀉湖区采集礁栖鱼类犬牙锥齿鲷(Pentapodus caninus)样本,对其体长和体质量、性比和性成熟度、摄食强度、肥满度、年龄与生长等生物学特征进行了研究。结果表明:5月和9月犬牙锥齿鲷的优势体长组分别为131～180 mm和131～150 mm,两个月份的群体体长和体质量均值在雌雄间差异极显著;性腺成熟度均以Ⅱ期为主,各月份雌性性腺成熟比例均高于雄性,初次性成熟体长126.4 mm;摄食等级以1级为主,5月17:30—23:00时段平均摄食强度最高,9月5:00—12:00、12:00—17:30、17:30—23:00三个时段摄食强度无显著差异;两个月份肥满度随体长增加均无显著变化;两个月份其体长和体质量关系异速生长因子b值分别为3.0856和3.0121; 28个耳石样本中,年龄为0.51～1.12龄,优势年龄组为0.60～0.80龄,占比39.29%;应用von Bertalanffy生长方程拟合犬牙锥齿鲷体长与年龄关系,生长参数分别为:L!=263.77 mm、k=0.71、t0=-0.52。     

甜瓜幼苗叶片光合变化特性

为探讨甜瓜光响应变化特性与环境因子的关系,选择光响应曲线适宜测定的时段,以甜瓜幼苗为试材,将1 d分为3个时段:10:00-12:00、12:00-15:00和15:00-17:00,每个叶位叶片测定1 d,并采用直角双曲线修正模型拟合光响应曲线,研究不同时段下甜瓜叶片光响应曲线、光响应参数的变化趋势和不同叶位叶片光响应参数特性。结果表明:当环境中光合有效辐射增强,叶面温度(Tl)升高,空气相对湿度(RH)降低;当环境中光合有效辐射减弱,Tl降低,RH升高。10:00-12:00光响应曲线和12:00-15:00的第1-4叶光响应曲线呈双曲线,在强光下趋向饱和状况,12:00-15:00的第5叶光合速率和15:00-17:00光合速率在强光下出现明显的光抑制现象。1 d的不同时段均表现为10:00-12:00最大净光合速率(P_max)和光饱和点(LSP)最高,12:00-17:00降低;12:00-15:00光补偿点(LCP)和暗呼吸速率(R_d)较高,其它两个时段较低,10:00-17:00光补偿点量子效率(φ_c)、气孔导度(G_s)和胞间CO₂浓度(C_i)总体呈降低趋势,气孔限制值(L_s)升高。10:00-15:00相同时段测得的不同叶位叶片光响应参数,以第4-5叶光合性能较好,15:00-17:00以第3叶P_max最高,第5叶次之;10:00-17:00 G_s和C_i以第5叶较低,第1叶较高,L_s以第5叶较高,第1叶较低。RH为影响P_max的主要决策因子,测定时段、叶面饱和蒸汽压亏缺(Vpdl)和Tl为主要限制因子。10:00-12:00适宜进行光响应曲线测定,气孔限制为不同时段光合作用不同的主要因素,非气孔限制为影响不同叶位叶片光合作用的主要因素。     

不同光照条件下叉尾斗鱼仔鱼摄食节律

在自然光照、持续光照和持续黑暗3种光照条件下,研究了孵化后第5、8和12日龄的叉尾斗鱼仔鱼的摄食节律。结果表明:自然光照下,3个日龄的叉尾斗鱼仔鱼在午后12:00—16:00表现出明显的摄食高峰,而持续光照组与持续黑暗组未表现出明显的摄食峰谷。持续光照下,叉尾斗鱼仔鱼的昼夜摄食活动均很活跃,全日各时段平均摄食量显著增加,尤其是夜晚20:00—翌日4:00各时段平均摄食量极显著高于同一时段自然光照组。而在持续黑暗下,与自然光照相比全日各时段平均摄食量明显减少,尤其是白天8:00—16:00各时段的平均摄食量极显著降低。叉尾斗鱼仔鱼属于典型的白天摄食类型,其摄食节律与光照条件密切相关。     

Twenty-four-hour and annual variation in onset of epistaxis in Osler disease

Osler disease is an autosomal dominant disorder of the fibrovascular tissue characterized by arteriovenous malformations with multi-systemic haemorrhages. Recurrent epistaxis is the predominant symptom in more than 90% of patients. Recent studies showed circadian and seasonal patterns in the onset of nosebleeds, similar to acute cardiovascular events, such as myocardial infarction and stroke. The aim of this study was to determine whether such patterns would also apply to the onset of epistaxis in patients with Osler disease. In all, 110 patients with Osler disease who were under treatment for recurrent epistaxis at the University Hospital of Mannheim were requested to complete a questionnaire addressing the intensity and frequency of epistaxis according to the classification of Bergler et al., as well as circadian and circannual rhythmicity in the occurrence of epistaxis according to visual analogue scales (VAS). More than half of the patients claimed to experience daily to weekly episodes of recurrent epistaxis. The occurrence of epistaxis showed a biphasic 24 h pattern, with a primary peak in the morning (05:00-8:00 h) and smaller secondary peaks in the evening (17:00-20:00 h and 21:00-00:00 h). No significant seasonal variation was found in the onset of epistaxis. However, a slight tendency, with a peak in winter months, was observed. Similar to other chronobiological studies on nosebleeds, this study showed that the 24 h pattern and seasonal tendency in the onset of epistaxis even applied to patients with Osler disease. Further investigations are necessary to determine the pathological mechanism underlying this phenomenon.     

MEWS系统在指导院前急性脑血管意外急救的临床应用

目的 探讨应用改良早期预警（MEWS）评分指导急性脑血管意外院前急救的临床价值.方法 将院前急救中临床诊断为急性脑血管意外的患者分为常规病情评估急救组（对照组）和进行现场MEWS评分指导急救组（实验组）,并比较两组患者的病死率及好转出院率.结果 对照组病死率为17.23%,好转出院率为82.77%;实验组病死率为8.76%,好转出院率为91.24%.两组比较,差异有统计学意义（P＜0.05）.结论 急性脑血管意外患者院前应用MEWS评分进行病情评估和指导急救,能降低患者的病死率及提高好转出院率,具有较好的应用价值,值得在院前脑血管意外急救中推广应用.     

心肺运动试验（CPET）评价个体化精准运动整体方案强化管控心脑血管慢病疗效的临床研究*

目的: 探讨研究症状限制性极限运动心肺运动试验（CPET）评价个体化精准运动整体方案强化管控3月后（简称强化管控）的长期慢病患者整体功能的改善。方法: 选取2014年至2016年由我们团队强化管控的长期心脑血管代谢慢病为主的患者20例,签署知情同意书后完成CPET,根据CPET及连续功能学检测结果制定以个体化适度运动强度为核心的整体管理方案,强化管控3月后再行CPET,个体化分析每例患者强化管控前后CPET指标的变化、计算差值和百分差值。结果: 本研究心脑血管代谢性慢病为主的患者20例（18男2女）,年龄（55.75±10.80,26~73）岁,身高（172.20±8.63,153~190）cm,体重（76.35±15.63,53~105）kg,所有患者CPET和强化管控期间均无任何危险事件发生。①强化管控后患者静态肺功能指标及静息收缩压、心率收缩压乘积和空腹血糖等均显著改善（P<0.05）。②强化管控前峰值摄氧量为（55.60±15.69,34.37~77.45）%pred和无氧阈为（60.11±12.26,43.29~80.63）%pred;强化管控后峰值耗氧量为（71.85±21.04,42.40~102.00）%pred和无氧阈为（74.95±17.03,51.90~99.47）%pred;管控后较管控前峰值摄氧量和无氧阈显著提高分别达（29.09±7.38,17.78~41.80）%和（25.16±18.38,1.77~81.86）%（P均<0.01）;其他核心指标峰值氧脉搏、峰值负荷功率、摄氧通气效率平台和递增功率运动持续时间均显著升高（P均<0.01）,二氧化碳排出通气效率最低值及二氧化碳排出通气斜率也显著好转（P<0.01）。③个体化分析而言,强化管控后15例上述8项CPET核心指标全部改善,另5例7项指标改善;全部病例峰值摄氧量（%pred）提高>15%以上,16例>20%,13例>25%,10例>30%。结论: CPET能安全客观定量地评估人体整体功能状态和治疗效果、指导制定个体化精准运动强度。个体化精准运动整体方案强化管控三个月能安全有效逆转长期心脑血管代谢等慢病患者的整体功能状态和异常指标。     

The CHANGE trial: no superiority of lifestyle coaching plus care coordination plus treatment as usual compared to treatment as usual alone in reducing risk of cardiovascular disease in adults with schizophrenia spectrum disorders and abdominal obesity

Life expectancy in patients with schizophrenia is reduced by 20 years for men and 15 years for women compared to the general population. About 60% of the excess mortality is due to physical illnesses, with cardiovascular disease being dominant. CHANGE was a randomized, parallel‐group, superiority, multi‐centre trial with blinded outcome assessment, testing the efficacy of an intervention aimed to improve cardiovascular risk profile and hereby potentially reduce mortality. A total of 428 patients with schizophrenia spectrum disorders and abdominal obesity were recruited and centrally randomized 1:1:1 to 12 months of lifestyle coaching plus care coordination plus treatment as usual (N=138), or care coordination plus treatment as usual (N=142), or treatment as usual alone (N=148). The primary outcome was 10‐year risk of cardiovascular disease assessed post‐treatment and standardized to age 60. At follow‐up, the mean 10‐year risk of cardiovascular disease was 8.4 ± 6.7% in the group receiving lifestyle coaching, 8.5 ± 7.5% in the care coordination group, and 8.0 ± 6.5% in the treatment as usual group (p=0.41). We found no intervention effects for any secondary or exploratory outcomes, including cardiorespiratory fitness, physical activity, weight, diet and smoking. In conclusion, the CHANGE trial did not support superiority of individual lifestyle coaching or care coordination compared to treatment as usual in reducing cardiovascular risk in patients with schizophrenia spectrum disorders and abdominal obesity.     

Time-Dependent Variations in the Coagulation Factors II, VII, IX, and X in Young and Elderly Volunteers

The existence of circadian (24-h) rhythms in the coagulation activity of vitamin K-dependent coagulation factors (Factors II, VII, IX, and X) were studied in six healthy young (18-30 years old) and six healthy elderly (69-75 years old) men. Aliquots of 5 ml of blood were obtained from each of the 12 subjects at six different time points over a 24-h period. Factors II, VII, and X were quantified by the prothrombin time test, whereas Factor IX was analyzed by the activated partial thromboplastin time test. Significant circadian variations were found for Factors II and VII in both age groups. The peak and trough values for Factor II were observed at 16: 00 and 00: 00 in young men and at 12: 00 and 16: 00 in elderly men. The amplitude of the rhythmic variation of Factor II was 3.3 ± 1.0 and 4.2 ± 0.9% in young and elderly volunteers, respectively. For Factor VII, the highest values were found during the activity period (08: 00-16: 00), while the lowest values occurred at night (00: 00) for both groups of subjects. The amplitude of the rhythms was twice as large in the young (6.2 ± 2.3%) as in the elderly (3.7 ± 0.8%). The data suggest that age does not alter significantly the chronobiology of Factors II and VII.     

Fluctuations in peripheral serum testosterone levels within a day, with age and by sexual stimulation in male beagle dogs bred indoors

Fluctuations in serum levels of testosterone (T) within a day, both with age and as a result of sexual stimulation, were examined in male beagle dogs. Eighty male dogs aged between 3 months and 16 years and bred in our laboratory were used under strictly controlled breeding conditions (temperature: 22 +/- 1 degree C, relative humidity: 55 +/- 5%, lighting time: 8:00 a.m.-8:00 p.m.). The level of T was measured by an RIA method. In order to examine the fluctuation in T level within a day, blood samples were obtained at 0:00, 6:00, 12:00 and 18:00 in each of five dogs aged 1.7 and 2.1 years. T levels fluctuated with a regular pattern that was lowest at 12:00, and increased to a peak at 18:00-6:00, thereafter decreasing until 12:00. In order to examine the change in T level with age, blood samples were obtained at 9:00, 12:00 and 16:00 from 70 dogs aged between 3 months and 16 years. The regular diurnal pattern of T level was usually seen, and the levels at 12:00 were always low and did not fluctuate at any age except for 6 months, and 13, 14 and 16 years. The T level at 9:00 increased to reach a peak at 4 years, whereas that at 16:00 did so at 2 years. T levels at 9:00 were significantly higher at 4-12 and 14 years than at 3 months, and were higher at 4 years than at 9 months.(ABSTRACT TRUNCATED AT 250 WORDS)     

某医院3945 份死亡病例死因分析

目的:探讨地处四川境内某医院3945例住院病人的死亡原因及其分布特征。方法:对2000年~2010年经某医院3945份死亡病例资料进行分析。结果:住院死亡病例主要死因为:恶性肿瘤、呼吸系统疾病、脑血管疾病、肝脏疾病、心血管疾病、消化道疾病、意外死亡、肾病、骨病变。男性死亡病例均明显高于女性,45岁以上年龄组占3/4主体比重。结论:交通事故仍然是主要意外死因,值得警惕;西南地区人们喜辛辣食物、酗酒、熬夜等不良生活习惯增大了引发致死疾病的几率;政府应加大综合预防保健与健康生活方式的引导力度;医院也应开展主要致死疾病针对性研究,加强收治工作。     

Temporal trends in cardiovascular demand in EMS: Weekday versus weekend differences

Diagnosed cardiovascular disease has well-reported temporal patterns, with demand distribution peaks in the late morning and greater case numbers on Mondays and in winter. We aimed to report temporal patterns of presumptive cardiovascular disease cases as determined after emergency medical services (EMS) assessment and to characterize the demand distribution by day of the week. We conducted a secondary analysis of all Ambulance Victoria cases in metropolitan Melbourne (Victoria, Australia) between January 2008 and December 2011. Analyzed data included time of call, incident mechanism, location type, final assessment (paramedic “diagnosis”) and patient age. We employed Poisson’s regression to analyze case numbers and trigonometric regression to quantify distribution patterns. The 182?983 cases of presumptive cardiovascular disease observed during the study period constituted 15.2% of total demand. The median age of persons attended was 72 (IQR 57–82) and there was an almost even split between genders (51% female). Peak numbers of most cardiovascular case types occurred between 09:00 and 11:00; the only exception was acute pulmonary edema, which had peak case numbers at 06:00. Trigonometric regression showed distinct time of day distribution patterns, which did not alter by season. Although weekend day demand was lower than on Mondays, due to a different distribution pattern, these differences were not constant over the 24-hour period. There were up to 27% fewer cases at 09:00 and up to 2.8% more cases at 01:00 on weekends compared to Mondays. We have shown that examination of presumptive cardiovascular disease using not only case counts but also demand distribution patterns allows for a greater understanding of ambulance demand. Monday might be the most frequent day for cardiovascular cases but different patterns of demand occur on weekends. Increased knowledge of when different types of cases are most likely to occur will help inform EMS planning, including paramedic capacity and resources.     

叶酸对心脑血管疾病二级预防作用的研究

目的:探讨叶酸对心脑血管疾病二级预防的效果。方法:326例恢复期心脑血管疾病患者以自愿的原则分为实验组(n=201)和对照组(n=125),对照组针对病因应用常规药物,实验组在针对病因常规用药的基础上应用叶酸,随访三年,所有患者均在实验前和半年后测一次血清同型半胱氨酸含量,同时记录对比两组心脑血管不良事件的发生率。结果:323例纳入统计,实验组和对照组在入选时同型半胱氨酸含量无差异(P>0.05),半年后实验组血清同型半胱氨酸含量显著低于对照组(P<0.05);心绞痛、心力衰竭、血栓形成等发生率差异均具有统计学意义(均为P<0.05),而在心肌梗死、脑梗死和病死率等方面差异没有统计学意义(P>0.05)。结论:叶酸在心脑血管疾病二级预防中可以降低心绞痛发生率、心力衰竭、血栓形成的发生率,对心肌梗死、脑梗死和病死率没有明显的影响。     

“Timing” of arrival and in-hospital mortality in a cohort of patients under anticoagulant therapy presenting to the emergency departments with cerebral hemorrhage: A multicenter chronobiological study in Italy

Therapy with oral anticoagulants (OACs) is a risk factor for cerebral hemorrhage (CH). Although different studies have been undertaken to investigate the timing of the onset of major cardiovascular events, no data exist on temporal patterns of the onset of CH in subjects treated with OACs. The aim of this study is to evaluate the timing of CH in patients treated with OACs. All patients who developed CH under OACs therapy and admitted to 28 Italian Emergency Departments (EDs) between September 2011 and July 2013 were enrolled. Age, sex, time and location of the hemorrhagic lesion, type of the bleeding events (idiopathic or post-traumatic), anticoagulant therapy (warfarin or new oral anticoagulants - NOAs) and time of ED admission (i.e., hour, day, month and season) were recorded. Five hundred and seventeen patients (63.2% male aged 80 ± 7.9 yrs) with CH were involved. Warfarin was taken by 494 patients (95.6%), and NOAs by 23 (4.4%). In-hospital mortality (IHM) was recorded in 208 cases (40.2%). Cosinor analysis showed a peak of CH arrival between 12:00 and 14:00 h both in the whole population (PR 73.9%, p = 0.002) and the male subgroup (PR 65.2%, p = 0.009), whereas females showed an anticipated morning peak between 08:00 and 10:00 h (PR 65.7%, p = 0.008). A further analysis between idiopathic and post-traumatic CH confirmed the presence of a 24 h pattern with a peak between 12:00 and 14:00 h (PR 58.5%, p = 0.019) and between 08:00 and 10:00 h (PR80.1%, p < 0.001) for idiopathic events and post-traumatic hemorrhages, respectively. Moreover, a seasonal winter peak was identified for idiopathic forms (PR 74%, p = 0.035), and a summer peak for post-traumatic forms (PR 77%, p = 0.025). The present study suggests the presence of a temporal pattern of ED arrivals in CH patients treated with OACs.