共查询到20条相似文献,搜索用时 109 毫秒
1.
Plasmonics - Surface plasmon resonance has many applications in designing biosensors. In this paper, an easy fabrication liquid crystal-based surface plasmon resonance (LC-SPR) biosensor is... 相似文献
2.
Xinyuan Chong Le Liu Zhiyi Liu Suihua Ma Jun Guo Yanhong Ji Yonghong He 《Plasmonics (Norwell, Mass.)》2013,8(2):1185-1191
We investigate the ability of a parallel scan spectral surface plasmon resonance imaging system in analyzing hybridization of single-stranded DNA (ssDNA) on microarray. The ssDNA probes are modified by a thiol group and thereby can be immobilized onto the gold film. Hybridization experiments are carried out by using both complementary and noncomplementary sequence to confirm the specificity of interaction. We also demonstrate that the data analysis is very important in reducing the noise and improving the resolution by comparing polynomial fitting method with the combination of polynomial fitting and centroid method. Finally, the results demonstrate that the parallel scan spectral surface plasmon resonance imaging system can be used for high-throughput analysis of the hybridization of the ssDNA. 相似文献
3.
Su Chia-Ying Lin Chun-Han Shih Pei-Ying Hsieh Chieh Yao Yu-Feng Tu Charng-Gan Chen Hao-Tsung Chen Horng-Shyang Kiang Yean-Woei Yang C. C. 《Plasmonics (Norwell, Mass.)》2016,11(3):931-939
Plasmonics - Surface plasmon (SP) coupling behaviors of an InGaN/GaN quantum well (QW) with surface plasmon polariton (SPP) induced on a smooth Ag-film/GaN interface and localized surface plasmon... 相似文献
4.
We present a new approach to surface plasmon microscopy with high refractive index sensitivity and spatial resolution that is not limited by the propagation length of surface plasmons. It is based on a nanostructured metallic sensor surface supporting Bragg-scattered surface plasmons. We show that these non-propagating surface plasmon modes are excellently suited for spatially resolved observations of refractive index variations on the sensor surface owing to their highly confined field profile perpendicular to as well as parallel to the metal interface. The presented theoretical study reveals that this approach enables reaching similar refractive index sensitivity as regular surface plasmon resonance (SPR) microscopy and offers the advantage of improved spatial resolution when observing dielectric features with lateral size <10???m for the wavelength around 800?nm and gold as the SPR-active metal. This paper demonstrates the potential of Bragg-scattered surface plasmon microscopy for high-throughput SPR biosensing with high-density microarrays. 相似文献
5.
Plasmonics - We investigated the field enhancement and lifetime of tuning surface plasmon in zero-thickness nanostructured graphene patches. The graphene surface plasmon (GSP) resonance mechanism... 相似文献
6.
Moreira Cleumar Wang Yunshan Blair Steve Carvalho Igor Cruz Rossana Santa 《Plasmonics (Norwell, Mass.)》2020,15(6):1891-1901
Plasmonics - An aluminum-based deep-ultraviolet surface plasmon resonance (DUV-SPR) sensor is promising for biological applications. Design aspects of a DUV-SPR sensor are here considered by using... 相似文献
7.
This paper analyzes how dual-mode surface plasmon resonance sensors can be further improved if one were to introduce small
(∼20 nm) gaps in the film surface. First, a figure of merit, the sensor’s limit of detection (LOD), is defined in order to
optimize the design of the nano-gap sensor. Secondly, the LOD of this design is compared with that of an optimized planar
dual-mode design. Through this analysis, it is shown that the LOD of the planar sensor can be improved upon by around a factor
of 7 when compared with the nano-gap-enhanced design. Furthermore, with the nano-gap design, the lower wavelength plasmon
mode demonstrates remarkably improved selectivity when compared with the conventional sensor. In order to explain these results,
the dispersion of each plasmon mode along with the electromagnetic field profiles are modeled and analyzed. 相似文献
8.
Pengfei Zhang Le Liu Yonghong He Yanhong Ji Jun Guo Hui Ma 《Plasmonics (Norwell, Mass.)》2016,11(3):771-779
We describe a temperature-regulated surface plasmon resonance (SPR) imaging biosensor in this article. The sample temperature can be regulated for specific requirements of the bioaffinity sensing, and stabilized to suppress the measurement noise caused by temperature fluctuations. The water thermo optic coefficient is measured to test the temperature regulation performance. The protein interaction is monitored to demonstrate the feasibility of this system for real-time biomolecular interaction analysis. This temperature-regulated SPR imaging biosensor can be readily implemented by adding the common water path and peristaltic pump to the conventional SPR imaging system, which may provide an economical and convenient scheme to improve the analysis accuracy and quality of bioaffinity sensing using SPR sensing platform. 相似文献
9.
High-resolution electron energy loss spectroscopy was used to investigate the surface plasmon dispersion in (111)-oriented Au films grown on Cu(111). The measured dispersion of the plasmon mode was positive, as found for Ag. The centroid of the induced charge associated to the plasmon field lies well inside the jellium edge. The damping relation of the Au surface plasmon presented a critical wave vector of 0.11 Å?1. For higher values of the parallel momentum transfer, the line width of Au surface plasmon considerably increased as a consequence of the opening of a new decay channel via single-particle transitions. 相似文献
10.
Wu Leiming Guo Jun Dai Xiaoyu Xiang Yuanjiang Fan Dianyuan 《Plasmonics (Norwell, Mass.)》2018,13(1):281-285
Plasmonics - Compared with surface plasmon resonance (SPR) biosensor, guided-wave surface plasmon resonance (GWSPR) biosensor has a higher sensitivity. In order to further enhance the sensitivity... 相似文献
11.
While an array of technologies based on radioactive labels or luminescent tags are dominant in modern biomedical research
on DNA, surface plasmon resonance (SPR) and SPR imaging measurements are sensitive, rapid, and label-free. This review summarizes
recent advances in the development of SPR and coupled techniques and their applications in DNA research, including the gene
analysis at trace levels and studies of DNA–protein and DNA–drug interactions. 相似文献
12.
Oleg A. Yeshchenko Igor M. Dmitruk Alexandr A. Alexeenko Andriy V. Kotko James Verdal Anatoliy O. Pinchuk 《Plasmonics (Norwell, Mass.)》2012,7(4):685-694
The surface plasmon energy in spherical silver nanoparticles embedded in silica host matrix depends on the size and temperature of the nanoparticles. The dependences of the surface plasmon energy were studied for silver nanoparticles in the size range 11?C30?nm and in the temperature interval 293?C650?K. As the size of the nanoparticles decreases or the temperature increases, the surface plasmon resonance shifts to red. When the size of the nanoparticles decreases, the scattering rate of the conduction electrons increases, which results in the nonlinear red shift of the surface plasmon resonance. The red shift with temperature is linear for larger nanoparticles and becomes nonlinear for smaller ones. As the temperature of the nanoparticles increases, the volume thermal expansion of the nanoparticles leads to the red shift of the surface plasmon resonance. The thermal volume expansion coefficient depends on the size and temperature. It increases with a decrease of the nanoparticle size and an increase of the temperature. 相似文献
13.
The objectives of this study were to establish an in-depth understanding of the signals induced by mammalian cells in surface plasmon resonance (SPR) sensing. To this end, two plasmonic structures with different propagation and penetration distances were used: conventional surface plasmon resonance and long-range surface plasmon resonance. Long-range SPR showed a lesser sensitivity to the absolute number of round cells but a greater resolution due to its very narrow spectral dip. The effect of cell spreading was also investigated and the resonance angle of long-range SPR was mostly insensitive unlike in the conventional SPR counterpart. Experimental data was compared with suitable models used in the SPR literature. Although these simple averaging models could be used to describe some of the experimental data, important deviations were observed which could be related to the fact that they do not take into consideration critical parameters such as plasmon scattering losses, which is particularly crucial in the case of long-range SPR structures. The comparison between conventional and long-range SPR for cellular schemes revealed important fundamental differences in their responses to the presence of cells, opening new horizons for SPR-based cell assays. From this study, long-range SPR is expected to be more sensitive towards both the detection of intracellular events resulting from biological stimulation and the detection of microorganisms captured from complex biological samples. 相似文献
14.
Surface Plasmon Resonance Imaging Sensors: A Review 总被引:1,自引:0,他引:1
Surface plasmon resonance (SPR) imaging sensors realize label-free, real-time, highly sensitive, quantitative, high-throughput biological interaction monitoring and the binding profiles from multi-analytes further provide the binding kinetic parameters between different biomolecules. In the past two decades, SPR imaging sensors found rapid increasing applications in fundamental biological studies, medical diagnostics, drug discovery, food safety, precision measurement, and environmental monitoring. In this paper, we review the recent advances of SPR imaging sensor technology towards high-throughput multi-analyte screening. Finally, we describe our multiplex spectral-phase SPR imaging biosensor for high-throughput biosensing applications. 相似文献
15.
Liu Chao Lv Jingwei Liu Zhaoting Zheng Shijie Liu Qiang Sun Tao Mu Haiwei Chu Paul K. 《Plasmonics (Norwell, Mass.)》2016,11(6):1589-1595
Plasmonics - The localized surface plasmon resonance (LSPR) properties of Au-interlayer-Ag multilayered nanoshells are studied by discrete dipole approximation (DDA) and plasmon hybridization... 相似文献
16.
Igor Dmitruk Ivan Blonskiy Ihor Pavlov Oleg Yeshchenko Alexandr Alexeenko Andriy Dmytruk Petro Korenyuk Viktor Kadan 《Plasmonics (Norwell, Mass.)》2009,4(2):115-119
New method of experimental determination of local field enhancement at metal nanoparticles is suggested. It uses surface plasmon
as a probe. Alternating-sign shift of surface plasmon resonance in copper nanoparticles incorporated in silica matrix has
been observed under irradiation by intense femtosecond laser pulse. The red shift of plasmon observed during the action of
pump pulse is interpreted as a result of change of dielectric constant of silica matrix due to optical Kerr effect in electric
field of pump pulse enhanced in a vicinity of metal nanoparticles. The field enhancement factor is estimated from the value
of the observed red shift of plasmon resonance. 相似文献
17.
Zhou Xiaodong Wong Ten It Song Hong Yan Wu Lin Wang Yi Bai Ping Kim Dong-Hwan Ng Sum Huan Tse Man Siu Knoll Wolfgang 《Plasmonics (Norwell, Mass.)》2014,9(4):835-844
Plasmonics - This paper describes our point-of-care system development based on localized surface plasmon resonance (LSPR). Although LSPR has been a hot research area for a few decades, there are... 相似文献
18.
Victor Yashunsky Vladislav Lirtsman Naomi Melamed-Book Dan Davidov 《Biophysical journal》2009,97(4):1003-1012
We report on the application of surface plasmon resonance (SPR), based on Fourier transform infrared spectroscopy in the mid-infrared wavelength range, for real-time and label-free sensing of transferrin-induced endocytic processes in human melanoma cells. The evanescent field of the mid-infrared surface plasmon penetrates deep into the cell, allowing highly sensitive SPR measurements of dynamic processes occurring at significant cellular depths. We monitored in real-time, infrared reflectivity spectra in the SPR regime from living cells exposed to human transferrin (Tfn). We show that although fluorescence microscopy measures primarily Tfn accumulation in recycling endosomes located deep in the cell's cytoplasm, the SPR technique measures mainly Tfn-mediated formation of early endocytic organelles located in close proximity to the plasma membrane. Our SPR and fluorescence data are very well described by a kinetic model of Tfn endocytosis, suggested previously in similar cell systems. Hence, our SPR data provide further support to the rather controversial ability of Tfn to stimulate its own endocytosis. Our analysis also yields what we believe is novel information on the role of membrane cholesterol in modulating the kinetics of endocytic vesicle biogenesis and consumption. 相似文献
19.
Lertvachirapaiboon Chutiparn Baba Akira Ekgasit Sanong Thammacharoen Chuchaat Shinbo Kazunari Kato Keizo Kaneko Futao 《Plasmonics (Norwell, Mass.)》2014,9(4):899-905
Plasmonics - In this study, we achieved an enhancement of the transmission surface plasmon resonance (T-SPR) intensity by depositing silver nanoparticles (AgNPs) onto a gold grating substrate. The... 相似文献
20.
Han Lei Chen Zhenxing Huang Tianye Ding Huafeng Wu Chuan 《Plasmonics (Norwell, Mass.)》2020,15(3):693-701
Plasmonics - The novel configuration of surface plasmon resonance (SPR) based on Ag-indium tin oxide (ITO)-transition metal dichalcogenides (TMDCs)-graphene hybrid structures is proposed for highly... 相似文献