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D.‐K. Kang 《Journal of applied microbiology》2017,122(3):554-567
The use of lactobacilli as probiotics in swine has been gaining attention due to their ability to improve growth performance and carcass quality, prevent gastrointestinal infection and most importantly, their ‘generally recognized as safe’ status. Previous studies support the potential of lactobacilli to regulate host immune systems, enhance gut metabolic capacities and maintain balance in the gut microbiota. Research on swine gut microbiota has revealed complex gut microbial community structure and showed the importance of Lactobacillus to the host's health. However, the species‐ and strain‐specific characteristics of lactobacilli that confer probiotic benefits are still not well understood. The diversity of probiotic traits in a complex gut ecosystem makes it challenging to infer the relationships between specific functions of Lactobacillus sp. and host health. In this review, we provide an overview of how lactobacilli play a pivotal role in the swine gut ecosystem and identify key characteristics that influence gut microbial community structure and the health of pigs. In addition, based on recent and ongoing meta‐omics and omics research on the gut microbiota of pigs, we suggest a workflow combining culture‐dependent and culture‐independent approaches for more effective selection of probiotic lactobacilli. 相似文献
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Selection of a candidate probiotic strain of Pediococcus pentosaceus from the faecal microbiota of horses by in vitro testing and health claims in a mouse model of Salmonella infection 下载免费PDF全文
B.C. Silva S.H.C. Sandes L.B. Alvim M.R.Q. Bomfim J.R. Nicoli E. Neumann A.C. Nunes 《Journal of applied microbiology》2017,122(1):225-238
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Selective method for identification and quantification of Bifidobacterium animalis subspecies lactis BB‐12 (BB‐12) from the gastrointestinal tract of healthy volunteers ingesting a combination probiotic of BB‐12 and Lactobacillus rhamnosus GG 下载免费PDF全文
D.D. Poutsiaka I.J. Mahoney L.A. McDermott L.L. Stern C.M. Thorpe A.V. Kane C. Baez‐Giangreco J. McKinney L.E. Davidson R. Leyva B. Goldin D.R. Snydman 《Journal of applied microbiology》2017,122(5):1321-1332
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Applications and safety considerations of Lactobacillus salivarius as a probiotic in animal and human health 下载免费PDF全文
The goals of this review are to summarize the current knowledge on the application of Lactobacillus salivarius as a probiotic in animals and humans, and to address safety concerns with its use on live hosts. Overall, several strains of L. salivarius are well established probiotics with multiple applications in animal health, particularly to reduce colonization by gastrointestinal pathogens, and to a lesser extent, as a production and quality aid. In humans, L. salivarius has been used to prevent and treat a variety of chronic diseases, including asthma, cancer, atopic dermatitis and halitosis, and to a much limited extent, to prevent or treat infections. Based on the results from primary research evidence, it seems that L. salivarius does not pose a health risk to animals or humans in the doses currently used for a variety of applications; however, there is a systematic lack of studies assuring the safety of many of the strains intended for clinical use. This review provides researchers in the field with up‐to‐date information regarding applications and safety of L. salivarius. Furthermore, it helps researchers identify knowledge gaps and potential opportunities for microbiological and clinical research. 相似文献
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Development and utility of the FDA ‘GutProbe’ DNA microarray for identification,genotyping and metagenomic analysis of commercially available probiotics 下载免费PDF全文
J.N. Patro P. Ramachandran J.L. Lewis M.K. Mammel T. Barnaba E.A. Pfeiler C.A. Elkins 《Journal of applied microbiology》2015,118(6):1478-1488
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