台湾海峡晚更新世人类肱骨化石

产自台湾海峡海底的人类右肱骨石化程度高; 个体大而粗壮 ,三角肌粗隆发育 ,骨干上下两半段不在同一纵轴上 ,形成 6 5°的夹角 ,这些显示不同于新石器时代和现代人的原始性状 ,其演化水平和日本的港川人及欧洲的克罗马农人相当。与人化石一同捞出的哺乳动物化石有古菱齿象、野马、最后鬣狗、达氏四不像鹿等 ,表明其时代为晚更新世晚期。     

封面图片简介

正2007年发掘的河北临城补要村遗址唐代土洞墓M15为男女两个体合葬墓。两个体人骨上下叠放在一起,均已成年。下层个体为中老年男性,头骨偏离正常解剖位置。其右侧顶、枕骨上有约10 cm长的砍痕,与右侧人字缝垂直。砍痕两端分别位于顶骨和枕骨上,并在顶骨、枕骨上形成骨裂。砍痕贯穿整个颅骨骨壁,是造成该个体死亡的直接原因。上层个体为中老年女性个体,各骨骼解剖位置基本正常。     

金丝猴颅骨及牙齿的比较形态研究

金丝猴(Rhinopithecus roxellanae M.-E.)自从1870年订名以来,对它的研究多限于分类和个体生态习性的观察描述,至于它的形态解剖方面的论述国内几无报道。国外Hooizer(1950)和Swindler(1976)对其牙齿作了简单扼要的描述,前者并在11例川金丝猴头骨中发现一例左侧上颌骨具有P⁴。这次我们对金丝猴系统的研究过程中,在解剖方面,除了进行各器官系统解剖外,同时还与猕猴、黑叶猴相比较,并对其器官的形态变化和生态生理机能的结合上给以适当注意和解释。     

人体的表面解剖和体表标志

为了使生理卫生教学更好地结合实际,提高学生学习解剖生理知识的兴趣,巩固、应用所学的知识,应让学生掌握部分人体的表面解剖和体表标志。现简单介绍如下,供教学参考。 (一) 上肢的表面解剖和体表标志 1.骨和关节 (1) 锁骨全长均可摸到。沿锁骨外端摸到肩峰、肩胛冈。肩峰在肩胛冈的外侧端,形成一个明显的骨缘,位于光滑的三角肌隆起的直上方,三角肌本身则覆盖在肱骨的大结节上。还能看到和摸到肩胛骨的内侧缘和胸锁关节。在肩胛骨外展时,在腋窝内可摸到肱骨头。     

锁定钢板固定术后内侧柱支撑能力与肱骨近端骨折患者预后的相关分析

目的:研究锁定钢板固定术后内侧柱的支撑能力与肱骨近端骨折患者预后的相关关系。方法:选取107例肱骨近端骨折患者作为研究对象,根据不同内侧柱支撑重建方式将所有患者分为四组,其中A组患者48例,均接受肱骨近端内侧骨皮质解剖复位以重建内侧柱支持;B组患者20例,均使用1枚支撑螺钉置入肱骨头内下方的软骨下骨,C组患者14例,均使用2枚或2枚以上支撑螺钉置入肱骨头内下方的软骨下骨;D组患者25例,均未进行肱骨近端内侧骨皮质解剖复位亦未使用锁定螺钉固定。比较各组患者术后Constant评分、VAS(visual analogue scale)评分、骨折愈合时间、肱骨头高度丟失值、肱骨头内翻角、并发症发生情况及二次手术率。结果:与无支撑重建组相比,骨皮质解剖复位组、单枚螺钉支撑重建组以及多枚螺钉支撑重建组的VAS评分、骨折愈合时间、肱骨头高度丟失值以及肱骨头内翻角均明显降低,而Constant评分明显升高,其中骨皮质解剖复位组的变化幅度最大多枚螺钉支撑重建组次之,单枚螺钉支撑重建组变化幅度最小,差异具有统计学意义(t=23.100,22.130,7.267,68.440,47.900,均P0.001);与无支撑重建组相比,骨皮质解剖复位组、单枚螺钉支撑重建组以及多枚螺钉支撑重建组的术后总并发症发生率和二次手术率均明显降低,其中骨皮质解剖复位组的降低幅度最大,单枚螺钉支撑重建组次之,多枚螺钉支撑重建组降低幅度最小差异具有统计学意义(X~2=12.938,11.904,P=0.005,0.008)。结论:锁骨钢板固定术后内侧柱的支撑能力与肱骨近端异型解剖钢板患者预后相关,内侧柱支撑能力的越高患者术后骨折愈合、肩关节恢复越佳,而并发症发生率以及二次手术率越低。     

双头联体的畸形蛇

1988年12月5日,在仁寿县黑龙滩发现1条活体黑眉锦蛇的双头幼蛇。此蛇全长42厘米,重17克。左侧头长1.7厘米,宽0.9厘米,右侧头长1.8厘米,宽1厘米;在右侧头吻至颈背2.5厘米处分叉呈“丫”形,左侧头向左外侧下方的倾斜度大;两个头之间以相邻的下颔皮肤相连。头背和体背鳞片均属正常。此蛇在海拔约500米的小山丘向阳坡面(离住宅十多米处)的土埂洞穴旁晒太阳时被采获。活动时右侧头抬正,掌握前进方向;左侧头则朝向左下方,其右眼随右侧头活动而转动,两个头的舌同步或不同步伸出。不活动时右侧头保持警戒状态,稍有惊扰,立即伸舌;左侧头眼的瞬膜浑浊,…     

宁夏石砚子墓地颅骨缺损个体的古病理学

本文对出土于宁夏东汉时期的石砚子墓地中一例罕见颅骨病理性损伤个体进行了古病理学诊断分析,该男性个体颅骨上可见不规则形大面积骨质破坏,累及额骨、左侧顶骨、左侧颞骨以及右侧顶骨,缺损周缘可见成骨性、溶骨性反应混合特征,呈向内、外翻卷状,边缘伴有骨膜反应,颅内壁可见较深血管压迹。通过CT影像分析骨骼损伤形态、骨骼损伤区域特征,并结合临床医学资料进行鉴别诊断,排除了朗格汉斯细胞组织细胞增生症、骨血管瘤、Gorham-Stout综合征、骨髓瘤和非特异性感染,推测该病例的病理诊断为甲状腺癌导致的继发性颅骨转移癌。     

神经节苷脂对大鼠缺血皮层自由基和丙二醛含量的影响

成年大鼠永久性结扎右侧颈总动脉,烧凝右侧大脑中动脉并暂时夹闭左侧颈总动脉,造成右侧皮层局灶性缺血模型。采用电子自旋共振(ESR)技术,测定右侧皮层组织的自由基水平;同时用比色法测定丙二醛(MDA)含量。发现动物缺血后12h右侧皮层的自由基和MDA含量均明显升高;而术中一次注射混合型神经节苷脂(GM,50mg/kg,ip)的动物,脑缺血后12h,自由基和MDA含量与正常对照动物比较无明显差别。阻断脑血流可导致皮层自由基增加,伴有自由基诱发的脂质过氧化产物MDA增多。GM通过抑制缺血皮层自由基的生成,减轻脂质过氧化程度,对缺血脑组织起到一定的保护作用。     

周口店5号直立人额骨眶上圆枕处的创伤痕迹

1966年在周口店第1地点发现的5号（ZKD-5）额顶骨和顶枕骨碎片是迄今唯一保存下来的周口店直立人头盖骨化石。以往研究发现，ZKD-5眶上圆枕处存在食肉类齿痕，该个体生前可能遭遇过鬣狗的捕食；虽资料记载周口店直立人头骨化石存在暴力冲突导致的创伤痕迹，但原始化石丢失，难以对其进行深入分析。本文以ZKD-5额顶骨化石为研究材料，通过肉眼、体视显微镜和CT技术，对其表面痕迹及骨骼内部解剖结构进行观察。结果显示ZKD-5额顶骨化石上除食肉类齿痕外，右侧眶上圆枕前侧及上侧存在多处不规则的创伤愈合痕迹，可能是暴力冲突过程中钝器击打所致的非致命伤，但不排除意外摔伤的可能性。ZKD-5的创伤痕迹是继南京人、马坝人及和县人之后，东亚地区中更新世古人类头骨创伤的新发现，为世界范围内中更新世古人类创伤记录增加了新的案例，为探讨周口店直立人的生存方式提供了参考资料。     

额叶EEG偏侧化预测情绪灵活性

随着社会竞争的日益加剧,人们在生活、学习、工作中都可能遇到各种与情绪有关的事件,如何根据情境的要求和个人的需要对情绪进行灵活性的反应,对每个人而言都至关重要.情绪灵活性的研究已成为情绪心理学、临床心理学、健康心理学等多个领域热衷讨论的课题.研究发现,左侧和右侧前额叶皮层半球不同程度地涉及加工和调节对情绪刺激的情绪反应,因此,额叶脑电图(EEG)偏侧化与情绪灵活性存在密切关系.但是,额叶EEG偏侧化是否是情绪灵活性的一个客观指标,以及额叶EEG偏侧化怎样预测情绪灵活性,至今仍不清楚.本研究测量了通过情绪电影范式诱发被试产生高兴、悲伤、愤怒、恐惧、厌恶等情绪过程中的额叶EEG活动.结果显示,情绪灵活性的激活模式反映的是情绪的动机维度,而不是情绪的效价维度.在静息状态下,对于与接近动机相关的情绪,额叶EEG左侧化的个体的左侧化程度增加;对于与回避动机相关的情绪,其左侧化程度降低.与之相对,静息状态额叶EEG右侧化的个体,无论对于与趋近动机相关的情绪还是与回避动机相关的情绪,额叶EEG偏侧化的程度没有发生改变.研究表明,额叶EEG偏侧化模式能够预测情绪灵活性,额叶EEG左侧化的个体有更灵活的情绪反应,额叶EEG右侧化的个体则有相对不灵活的情绪反应.     

Nuclear medicine studies of aging—VII. Humeral deltoid tuberosity on bone scans and radiographs

Because of the occasional finding of increased deposition of bone imaging agent in the area of the humeral deltoid tuberosity, we analyzed both bone scans and radiographs to determine if there were age related correlations. Only 29% of patients of age 35 years or younger showed any radiographie evidence of deltoid tuberosity. This increased to 48% in the 36–64 y age group (and 46% in those of age 65 y and above). Bone scans (^99mTc-MDP) of the humerus showed that 26% of individuals of ages 20–39 y had increased uptake in the deltoid tuberosity area. The figure was 21% of those in the 85–94 y age group. However, distribution between sexes in the 20–39 y age cohort was asymmetric (44% of males showed the bone scan finding, but only 15% of the females). We then reviewed cases that had shown the most prominent deltoid tuberosity on humeral radiographs. Thirteen of the 14 cases (93%) were males. Deposition of bone imaging agent in the deltoid tuberosity region was thus only slightly correlated with age (more common after age 35 y), but strongly correlated with sex (males more common) in all three major age groups (35 and under, 36–64, and 65 years and over). Possible interrelations with bone size and muscle mass were pointed out.     

Influence du muscle deltoïde sur la courbure du corps de l’humérus chez les hommes modernes et les Néandertaliens

When observed in medial view, the humeral diaphysis shows two main types of curvature. It can be either more or less regularly distributed along the bone, or distally deported. Both types are about equally represented among modern humans, while the “regular” type largely prevails in Neandertals. Our hypothesis is that the distal curvature is the resultant of the action of the triceps brachial that “pulls” the bone in the posterior direction and of the deltoid that, in some cases, would be powerful enough to “straighten” the superior part of the diaphysis. Our results indicate that, in modern humans, bones with a distal curvature are indeed more frequent in males and on the right side and that their deltoid tuberosity is on average wider, more developed and more prominent as compared to bones with a regular curvature. This suggests a stronger solicitation of the deltoid muscle associated to this morphology. The high percentage of humeri showing a regular curvature observed in Neandertals would therefore be explainable by the fact that their deltoid tuberosity is averagely narrow, poorly developed and forming a weak prominence which likely attests of a moderate activity of this muscle in most of them.     

The Structure of the Upper End of the Humerus with Reference to Osteoporotic Changes in Senescence Leading to Fractures

Fractures of the upper humerus occur most commonly in elderly women. Humeri from cadavers of 20 aged individuals were sectioned in one of three planes and examined radiographically. The greater tuberosity was found to be cavitated and the shaft is devoid of cancellous tissue in older bones, but the scar of the epiphyseal plate persists. Cortical bone is very thin at the lower part of the greater tuberosity and humeral head where fracture most commonly occurs. Two major groups of vertical trabeculae are found. The head has its own trabecular system.     

Limb bone bilateral asymmetry: variability and commonality among modern humans

Humans demonstrate species-wide bilateral asymmetry in long bone dimensions. Previous studies have documented greater right-biases in upper limb bone dimensions--especially in length and diaphyseal breadth--as well as more asymmetry in the upper limb when compared with the lower limb. Some studies have reported left-bias in lower limb bone dimensions, which, combined with the contralateral asymmetry in upper limbs, has been termed "crossed symmetry." The examination of sexual dimorphism and population variation in asymmetry has been limited. This study re-examines these topics in a large, geographically and temporally diverse sample of 780 Holocene adult humans. Fourteen bilateral measures were taken, including maximum lengths, articular and peri-articular breadths, and diaphyseal breadths of the femur, tibia, humerus, and radius. Dimensions were converted into percentage directional (%DA) and absolute (%AA) asymmetries. Results reveal that average diaphyseal breadths in both the upper and lower limbs have the greatest absolute and directional asymmetry among all populations, with lower asymmetry evident in maximum lengths or articular dimensions. Upper limb bones demonstrate a systematic right-bias in all dimensions, while lower limb elements have biases closer to zero %DA, but with slight left-bias in diaphyseal breadths and femoral length. Crossed symmetry exists within individuals between similar dimensions of the upper and lower limbs. Females have more asymmetric and right-biased upper limb maximum lengths, while males have greater humeral diaphyseal and head breadth %DAs. The lower limb demonstrates little sexual dimorphism in asymmetry. Industrial groups exhibit relatively less asymmetry than pre-industrial humans and less dimorphism in asymmetry. A mixture of influences from both genetic and behavioral factors is implicated as the source of these patterns.     

Myf5 −/− :MyoD −/− amyogenic fetuses reveal the importance of early contraction and static loading by striated muscle in mouse skeletogenesis

The mechanical loading of striated muscle is thought to play an important role in shaping bones and joints. Here, we examine skeletogenesis in late embryogenesis (embryonic day 18.5) in Myf5 ^−/− :MyoD ^−/− fetuses completely lacking striated muscle. The phenotype includes enlarged and fused cervical vertebrae and postural anomalies, some viscerocranial anomalies, long bone truncation and fusion, absent deltoid tuberosity of the humerus, scapular and clavicular hypoplasia, cleft palate, and cleft sternum. In contrast, neurocranial bone development was essentially normal. While the magnitude of individual effects varied throughout the skeletal system, the results are consistent with skeletal development depending on functional muscles. Novel abnormalities in the amyogenic fetuses relative to less severely paralyzed phenotypes extend our understanding of skeletogenic dependence on embryonic muscle contraction and static loading. I. Rot-Nikcevic, T. Reddy, and K.J. Downing contributed equally to this work.     

Bilateral asymmetry in the limb bones of the chimpanzee (Pan troglodytes)

There is much debate in behavioral primatology on the existence of population-level handedness in chimpanzees. The presence or absence of functional laterality in great apes may shed light on the origins of human handedness and on the evolution of cerebral asymmetry. The plasticity of long bone diaphyses in response to mechanical loading allows the functional interpretation of differences in cross-sectional geometric. While left-right asymmetry in upper limb diaphyseal morphology is a known property in human populations, it remains relatively unexplored in apes. We studied bilateral asymmetry in 64 skeletons of wild-caught chimpanzee using the humerus, second metacarpal, and femur. The total subperiosteal area (TA) of the diaphyses was measured at 40% of maximum humeral length and at the midshaft of the metacarpals and femora using external silicone molds. Overall, the TA values of the left humeri were significantly greater than the right, indicating directional asymmetry. This effect was even greater when the magnitude of difference in TA between each pair of humeri was compared. The right second metacarpals showed a tendency toward greater area than did the left, but this did not reach statistical significance. The lack of asymmetry in the femur serves as a lower limb control, and suggests that the upper limb results are not a product of fluctuating asymmetry. These findings imply behavioral laterality in upper limb function in chimpanzees, and suggest a complementary relationship between precision and power.     

Habitual throwing and swimming correspond with upper limb diaphyseal strength and shape in modern human athletes

Variation in upper limb long bone cross‐sectional properties may reflect a phenotypically plastic response to habitual loading patterns. Structural differences between limb bones have often been used to infer past behavior from hominin remains; however, few studies have examined direct relationships between behavioral differences and bone structure in humans. To help address this, cross‐sectional images (50% length) of the humeri and ulnae of university varsity‐level swimmers, cricketers, and controls were captured using peripheral quantitative computed tomography. High levels of humeral robusticity were found in the dominant arms of cricketers, and bilaterally among swimmers, whereas the most gracile humeri were found in both arms of controls, and the nondominant arms of cricketers. In addition, the dominant humeri of cricketers were more circular than controls. The highest levels of ulnar robusticity were also found in the dominant arm of cricketers, and bilaterally amongst swimmers. Bilateral asymmetry in humeral rigidity among cricketers was greater than swimmers and controls, while asymmetry for ulnar rigidity was greater in cricketers than controls. The results suggest that more mechanically loaded upper limb elements––unilaterally or bilaterally––are strengthened relative to less mechanically loaded elements, and that differences in mechanical loading may have a more significant effect on proximal compared to distal limb segments. The more circular humerus in the dominant arm in cricketers may be an adaptation to torsional strain associated with throwing activities. The reported correspondence between habitual activity patterns and upper limb diaphyseal properties may inform future behavioral interpretations involving hominin skeletal remains. Am J Phys Anthropol 2009. © 2009 Wiley‐Liss, Inc.     

Comparative forelimb morphology of scratch-digging and chisel-tooth digging African mole-rat species

Bathyergus suillus (Cape dune mole-rat) and Heterocephalus glaber (naked mole-rat) are two species of subterranean burrowing rodents. Bathyergus suillus occurs in soft sandy soils and is regarded as a scratch-digger, while H. glaber is found in hard, compact soils and is a chisel-tooth digging species. The present study aimed to determine musculoskeletal differences in the forelimb of these two species. The muscles of the forelimb, back and neck were dissected to the points of origin and insertion in the left and right forelimbs, B. suillus (n = 7) and H. glaber (n = 5). Dissected muscles were photographed before maceration to demonstrate muscle attachments. The scapular spine, acromion process and clavicle were relatively straight in B. suillus. In comparison a curved scapular spine, acromion process and clavicle were observed in H. glaber. In both species, the clavicle rested on the greater tuberosity of the humerus. In B. suillus, the deltoid tuberosity was prominent and situated more distally on the humeral shaft compared to the indistinct, more proximally situated deltoid tuberosity in H. glaber. A prominent bony structure underlying the thenar pad as well as a cartilaginous protrusion beneath the hypothenar pad were observed on the palmar surface of the manus in B. suillus. Prominent claws were observed in B. suillus. A robust m. sternohyoideus was observed in H. glaber while mm. tensor fasciae antebrachii and coracobrachialis were absent. The flexors of the antebrachium of B. suillus had additional and enlarged attachment sites. The forelimb of B. suillus may be morphologically adapted for scratch-digging with relatively large and additional forelimb muscles and robust bones. In comparison, H. glaber had a reduction in the relative size, amount of muscles as well as number of attachment sites in the forelimb muscles, while the well-developed ventral neck muscles may facilitate neck and head stabilisation during chisel-tooth digging.     

The phylogeny and ontogeny of humeral torsion

In a series of specimens extending from fossil material through recent vertebrates including man there occurs a gradual phylogenetic increase in the degree of humeral torsion. A further (ontogenetic) torsion is superimposed upon the phylogenetic one in man which increases from birth until the proximal epiphysial cartilage of the humerus disappears and bony fusion occurs. There is a distinct correlation between the calculated strength of humeral rotator muscles inserting above and below the proximal epiphysis; this suggests that they provide the forces involved in the production of humeral torsion. It is shown that ontogenetic or secondary torsion occurs proximally and not along the shaft of the bone. Differences in the degree of humeral torsion in either sex of adult Whites and Negroes are given and discussed.     

Comparative evaluation of scapular and humeral coordinate systems based on biomedical images of the glenohumeral joint

Bio-imaging techniques represent a powerful tool for shoulder joint biomechanical analysis. However, the restricted field of view may prevent the acquisition of complete scapula and humerus bone models and hence limiting the applicability of standardized anatomical coordinate system (ACS) definitions. The aim of this study was to propose ACS definitions for both scapula and humerus which can be implemented when limited portions of the relevant bones are available. Magnetic resonance (MR) images of twenty right humeri and scapulae were acquired. The proposed ACSs were assessed in terms of (1) sensitivity to bone morphological variation, (2) intra – and inter – operator repeatability and (3) consistency with the anatomical cardinal directions. A comparison with alternative ACS definitions was also performed. Overall, our ACS scapular proposal and that presented in Kedgley and Dunning (2010) were found to be the least sensitive to the morphometric variability (mean angular absolute deviation lower than 8.3 deg) and they were characterized by a high intra – and inter – operator repeatability (mean angular absolute deviation lower than 1.5 deg). The humeral ACS proposal showed a morphometric variability similar to Amadi et al. (2009b) (mean angular absolute deviation lower than 8.3 deg) but a higher reproducibility. The scapular and humeral ACS mean angular deviation from the reference anatomical cardinal directions were smaller than 15 deg and 8.6 deg, respectively. The proposed scapular and humeral ACS definitions are therefore suitable to be applied when a limited portion of the glenohumeral joint is available as it may occur in standard shoulder clinical exams.