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1.
David B. Allison M. Katherine Hoy Angelique Fournier Steven B. Heymsfield 《Obesity (Silver Spring, Md.)》1993,1(6):425-432
In the United States, obesity is more common among black and Hispanic than white women. One putative cause of this difference is different cultural norms for attractiveness. Two studies assessed ethnic differences in men's perceptions of the attractiveness of females of varying sizes. In the fmst, 108 men recruited on the New York subway were shown sets of silhouettes depicting female bodies varying in fatness and were asked to pick the silhouette they found most attractive. They were also asked to indicate the thinnest and fattest figures they would consider dating. A measure of “latitude of acceptance” was computed as the difference between the thinnest and fattest figures considered. Results indicated no relationship between ethnicity and preference (F = 1.383, p =.257) or “latitude” (F =.102, p =.903). In Study 2, “personal advertisements” placed by 373 black, 1915 white, 110 Hispanic, and 30 Asian men from 35 newspapers and magazines were coded as: 1) thinness preferred; 2) no information on weight preference; 3) fatness preferred; or 4) states weight or looks unimportant. Results indicated a statistically significant but small association between ethnicity and preference (χ2 = 49.55, df=9, p<.00001). Relative to white and Asian men, black and Hispanic men more frequently requested fat women, Hispanic men less frequently requested thin women, and black men more frequently stated that looks or weight did not matter. Ethnicity explained only 2.1% of the variance in preference. Thus, it seems unlikely that ethnic differences in men's preferences for women's body shapes contribute substantially to ethnic differences in female adiposity. 相似文献
2.
Jennifer M. D. Yoon Nathan Witthoft Jonathan Winawer Michael C. Frank Daniel L. Everett Edward Gibson 《PloS one》2014,9(11)
Visual illusions and other perceptual phenomena can be used as tools to uncover the otherwise hidden constructive processes that give rise to perception. Although many perceptual processes are assumed to be universal, variable susceptibility to certain illusions and perceptual effects across populations suggests a role for factors that vary culturally. One striking phenomenon is seen with two-tone images—photos reduced to two tones: black and white. Deficient recognition is observed in young children under conditions that trigger automatic recognition in adults. Here we show a similar lack of cue-triggered perceptual reorganization in the Pirahã, a hunter-gatherer tribe with limited exposure to modern visual media, suggesting such recognition is experience- and culture-specific. 相似文献
3.
Jacqueline M. Vink Meike Bartels Toos C. E. M. van Beijsterveldt Jenny van Dongen Jenny H. D. A. van Beek Marijn A. Distel Marleen H. M. de Moor Dirk J. A. Smit Camelia C. Minica Lannie Ligthart Lot M. Geels Abdel Abdellaoui Christel M. Middeldorp Jouke Jan Hottenga Gonneke Willemsen Eco J. C. de Geus Dorret I. Boomsma 《PloS one》2012,7(12)
We examined sex differences in familial resemblance for a broad range of behavioral, psychiatric and health related phenotypes (122 complex traits) in children and adults. There is a renewed interest in the importance of genotype by sex interaction in, for example, genome-wide association (GWA) studies of complex phenotypes. If different genes play a role across sex, GWA studies should consider the effect of genetic variants separately in men and women, which affects statistical power. Twin and family studies offer an opportunity to compare resemblance between opposite-sex family members to the resemblance between same-sex relatives, thereby presenting a test of quantitative and qualitative sex differences in the genetic architecture of complex traits. We analyzed data on lifestyle, personality, psychiatric disorder, health, growth, development and metabolic traits in dizygotic (DZ) same-sex and opposite-sex twins, as these siblings are perfectly matched for age and prenatal exposures. Sample size varied from slightly over 300 subjects for measures of brain function such as EEG power to over 30,000 subjects for childhood psychopathology and birth weight. For most phenotypes, sample sizes were large, with an average sample size of 9027 individuals. By testing whether the resemblance in DZ opposite-sex pairs is the same as in DZ same-sex pairs, we obtain evidence for genetic qualitative sex-differences in the genetic architecture of complex traits for 4% of phenotypes. We conclude that for most traits that were examined, the current evidence is that same the genes are operating in men and women. 相似文献
4.
Differences in host behavior and resistance to disease can influence the outcome of host-pathogen interactions. We capitalized on the variation in aggregation behavior of Fowler''s toads (Anaxyrus [ = Bufo] fowleri) and grey treefrogs (Hyla versicolor) tadpoles and tested for differences in transmission of Batrachochytrium dendrobatidis (Bd) and host-specific fitness consequences (i.e., life history traits that imply fitness) of infection in single-species amphibian mesocosms. On average, A. fowleri mesocosms supported higher Bd prevalences and infection intensities relative to H. versicolor mesocosms. Higher Bd prevalence in A. fowleri mesocosms may result, in part, from higher intraspecific transmission due to the aggregation of tadpoles raised in Bd treatments. We also found that, independent of species, tadpoles raised in the presence of Bd were smaller and less developed than tadpoles raised in disease-free conditions. Our results indicate that aggregation behavior might increase Bd prevalence and that A. fowleri tadpoles carry heavier infections relative to H. versicolor tadpoles. However, our results demonstrate that Bd appears to negatively impact larval growth and developmental rates of A. fowleri and H. versicolor similarly, even in the absence of high Bd prevalence. 相似文献
5.
The objective of the present investigation was to examine the extent of variations in single leaf net photosynthetic rate
(PN) and its relative dependence on stomatal conductance (gs) and the mesophyll capacity to fix carbon in 12 clones of the natural rubber plant. There were significant variations in
PN measured at low and saturating photon flux density (PFD); the extent of variation was larger at low than at saturating PFD.
The compensation irradiance (CI) and apparent quantum yield of CO2 assimilation (φc) calculated from the PN/PFD response curves showed significant variations among the clones. PN at low irradiance was positively correlated with φc. Thus a clone with large PN at low irradiance, high φc, and low CI may tolerate shade better and thus produce a high tree stand per hectare. A strong positive correlation existed
between PN saturated with radiant energy (Psat) and carboxylation efficiency (CE) estimated from the response curves of PN on intercellular CO2 concentration (Ci), but gs showed a poor correlation with Psat High CO2 compensation concentration (Γ) led to low CE in Hevea clones. A clone with large Psat, high CE, low gs, and low Γ is the one in which photosynthesis is more dependent on the mesophyll factors than stomata. Such a clone may produce
relatively high biomass and maintain high water use efficiency.
This revised version was published online in September 2006 with corrections to the Cover Date. 相似文献
6.
Experimental populations of Drosophila simulans were established for the purpose of detecting the presence or absence of selection on a restriction fragment length polymorphism in mitochondrial DNA (mtDNA). It was then discovered that the founding strains differed with respect to the Rickettsia-mediated incompatibility system in this species, which is maternally transmitted together with the mtDNA differences. A population model was constructed using the known fitness effects of the incompatibility system, with the result that the population trajectories can be completely explained by the effects of the microorganism with no need to invoke selection on mtDNA. The strong conclusion is that in this case we can rule out the strong selection proposed by MacRae and Anderson to explain the "dramatic mtDNA changes" in their Drosophila pseudoobscura populations. The population theory used for the experiments is discussed in the context of natural populations. Estimated parameters include the possibility that with two populations, one with the organism and one without it, there may be no bias as to which will invade the other, which in turn suggests no global tendency for the infection to spread or decline. 相似文献
7.
Background
It is well documented that East Asians differ from Westerners in conscious perception and attention. However, few studies have explored cultural differences in unconscious processes such as implicit learning.Methodology/Principal Findings
The global-local Navon letters were adopted in the serial reaction time (SRT) task, during which Chinese and British participants were instructed to respond to global or local letters, to investigate whether culture influences what people acquire in implicit sequence learning. Our results showed that from the beginning British expressed a greater local bias in perception than Chinese, confirming a cultural difference in perception. Further, over extended exposure, the Chinese learned the target regularity better than the British when the targets were global, indicating a global advantage for Chinese in implicit learning. Moreover, Chinese participants acquired greater unconscious knowledge of an irrelevant regularity than British participants, indicating that the Chinese were more sensitive to contextual regularities than the British.Conclusions/Significance
The results suggest that cultural biases can profoundly influence both what people consciously perceive and unconsciously learn. 相似文献8.
9.
Beata Jurecka-Lubieniecka Tomasz Bednarczuk Rafal Ploski Jolanta Krajewska Dorota Kula Malgorzata Kowalska Andrzej Tukiendorf Zofia Kolosza Barbara Jarzab 《PloS one》2016,11(3)
Background
Graves’ disease (GD) is a complex disease in which genetic predisposition is modified by environmental factors. Each gene exerts limited effects on the development of autoimmune disease (OR = 1.2–1.5). An epidemiological study revealed that nearly 70% of the risk of developing inherited autoimmunological thyroid diseases (AITD) is the result of gene interactions. In the present study, we analyzed the effects of the interactions of multiple loci on the genetic predisposition to GD. The aim of our analyses was to identify pairs of genes that exhibit a multiplicative interaction effect.Material and Methods
A total of 709 patients with GD were included in the study. The patients were stratified into more homogeneous groups depending on the age at time of GD onset: younger patients less than 30 years of age and older patients greater than 30 years of age. Association analyses were performed for genes that influence the development of GD: HLADRB1, PTPN22, CTLA4 and TSHR. The interactions among polymorphisms were analyzed using the multiple logistic regression and multifactor dimensionality reduction (MDR) methods.Results
GD patients stratified by the age of onset differed in the allele frequencies of the HLADRB1*03 and 1858T polymorphisms of the PTPN22 gene (OR = 1.7, p = 0.003; OR = 1.49, p = 0.01, respectively). We evaluated the genetic interactions of four SNPs in a pairwise fashion with regard to disease risk. The coexistence of HLADRB1 with CTLA4 or HLADRB1 with PTPN22 exhibited interactions on more than additive levels (OR = 3.64, p = 0.002; OR = 4.20, p < 0.001, respectively). These results suggest that interactions between these pairs of genes contribute to the development of GD. MDR analysis confirmed these interactions.Conclusion
In contrast to a single gene effect, we observed that interactions between the HLADRB1/PTPN22 and HLADRB1/CTLA4 genes more closely predicted the risk of GD onset in young patients. 相似文献10.
Scholtens S Brunekreef B Smit HA Gast GC Hoekstra MO de Jongste JC Postma DS Gerritsen J Seidell JC Wijga AH 《Obesity (Silver Spring, Md.)》2008,16(11):2498-2503
Breastfeeding has been associated with a reduced risk of overweight later in life. This study investigates whether differences in diet and lifestyle at 7 years of age between breastfed and formula-fed children can explain the difference in overweight prevalence at 8 years of age. We studied 2,043 Dutch children born in 1996-1997 who participated in the Prevention and Incidence of Asthma and Mite Allergy birth cohort study. Data on breastfeeding duration and diet and lifestyle factors at 7 years were collected using questionnaires. Weight and height were measured at 8 years. Overweight was defined according to international gender- and age-specific standards. Compared to nonbreastfed children (15.5%, n = 316), children breastfed for >16 weeks (38.0%, n = 776) consumed fruit and vegetables significantly more often and meat, white bread, carbonated soft drinks, chocolate bars, and fried snacks less often. Overall, breastfed children were less likely to have an unhealthy diet (adjusted prevalence ratio: 0.77, 95% confidence interval: 0.61-0.98). The associations could only partly be explained by maternal education, maternal overweight, and smoking during pregnancy. At 8 years, 14.5% (n = 297) of the children were overweight. Breastfeeding for >16 weeks was significantly associated with a lower overweight risk at 8 years (adjusted odds ratio: 0.67, 95% confidence interval: 0.47-0.97), and the association hardly changed after adjustment for diet (adjusted odds ratio: 0.71, 95% confidence interval: 0.49-1.03). Breastfed children had a healthier diet at 7 years compared to nonbreastfed children, but this difference could not explain the lower overweight risk at 8 years in breastfed children. 相似文献
11.
Stephanie Yue Ian J. H. Duncan Richard D. Moccia 《Environmental Biology of Fishes》2006,76(2-4):425-431
Little is known about the cognitive and subjective experiences of fish that are confined with conspecifics of varying body sizes. Plasma cortisol and several behavioural variables were recorded when a ȁ8mediumȁ9 sized fish had its familiar social group (comprised of medium, like-sized individuals) replaced with a group of fish that were either medium sized, smaller or larger than itself. Interestingly, the medium sized test fish showed very few behavioural responses indicative of stress when exposed to a new social cohort. Fish did not use a particular part of their tank, or water column, nor did they show any significant change in locomotory behaviour. There was no difference in aggressive ȁ8chasingȁ9 behaviour in any of the treatments, however, medium sized fish were frequently chased by their tank-mates when exposed to the ȁ8largeȁ9 fish treatment, and were almost never chased by fish smaller than themselves. Similarly, plasma cortisol concentrations did not differ between fish that were exposed to different size treatment groups, although there was a high increase above baseline levels; this suggests that encounters with unfamiliar fish were stressful, regardless of size. 相似文献
12.
Hans P. A. Van Dongen 《Chronobiology international》2013,30(6):1139-1147
Inter‐individual differences in tolerance for shift work have been studied primarily in terms of external factors affecting alertness on the job or the ability to rest and sleep while at home. However, there is increasing evidence that neurobiological factors play a role as well, particularly the major processes involved in the regulation of sleep and wakefulness. These include a sleep homeostatic process seeking to balance wakefulness and sleep and a circadian process seeking to promote wakefulness during the day and sleep during the night. Shift work is associated with a temporal misalignment of these two endogenous processes. During nightwork, this misalignment makes it difficult to stay awake during the nightshift and sleep during the day. However, inter‐individual variability in the processes involved in sleep/wake regulation is substantial. Recent studies have demonstrated the existence of inter‐individual differences in vulnerability to cognitive deficits from sleep loss. Moreover, these inter‐individual differences were shown to constitute a trait. Interestingly, self‐evaluations of sleepiness did not correspond well with the trait inter‐individual variability in objective levels of performance impairment during sleep deprivation. Perhaps because of this discrepancy, in operational settings, the inter‐individual differences in vulnerability to sleep loss do not appear to be limited due to self‐selection mechanisms. Indeed, even among a highly select group of active‐duty jet fighter pilots flying a series of simulated night missions, systematic inter‐individual differences in performance impairment from sleep loss were still observed. There are significant personal and economic consequences to human error and accidents caused by performance deficits due to sleep loss. It is important, therefore, to study the inter‐individual differences in the regulation of sleep and wakefulness in the work environment so that cognitive impairment during shift work may be better anticipated and prevented. 相似文献
13.
《Gender Medicine》2007,4(4):359-366
Background: Sensitivity to cold is associated with several factors, such as aging, sex, and body composition. However, no previous studies have examined the differences in sensitivity to cold in men and women or the association of hormonal levels with sensitivity to cold.Objective: The aim of the present study was to clarify both the change in sensitivity to cold with aging and the difference in sensitivity to cold between men and women. Associations were also examined between circulating hormonal concentrations and the changes with aging and differences in sensitivity.Methods: This population-based cohort study enrolled healthy Japanese men and women aged ≥ 50 years. A standardized 210-item health questionnaire was used to obtain information on symp- toms of sensitivity to cold. Serum concentrations of luteinizing hormone, follicle-stimulating hor- mone (FSH), estradiol, testosterone, dehydroepiandrosterone sulfate, and sex hormone-binding globu- lin (SHBG) were measured.Results: Of the 154 men and 180 women enrolled in this study, more women than men had sensitivity to cold. Whereas the percentage of men who had sensitivity to cold significantly increased with aging (P < 0.05), the percentage of women who had sensitivity to cold was already high (23.7%) at 50 to 60 years of age and did not change with aging. In men, advancing age and low body mass index (BMI) were significantly associated with sensitivity to cold (P < 0.05); however, age and BMI in women were not similarly associated. In addition, the effect of sex after adjustment for age was significant (P < 0.05), and there was also a numeric but nonsignificant effect of sex after adjustment for BMI. In men, low serum levels of the gonadal hormone FSH were significantly associated with sensitivity to cold in logistic analysis, but this association was nonsignificant after multivariate analysis. Serum concentrations of gonadal hormones and SHBG in women were not associated with sensitivity to col.Conclusions: The association of age with sensitivity to cold was different in men and women; the association of BMI with sensitivity to cold might be different in men and women. In addition, these changes in sensitivity to cold were not associated with circulating hormonal concentrations. 相似文献
14.
Age is often associated with a decline in cognitive abilities that are important for maintaining functional independence, such as learning new skills. Many forms of motor learning appear to be relatively well preserved with age, while learning tasks that involve associative binding tend to be negatively affected. The current study aimed to determine whether age differences exist on a configural response learning task, which includes aspects of motor learning and associative binding. Young (M = 24 years) and older adults (M = 66.5 years) completed a modified version of a configural learning task. Given the requirement of associative binding in the configural relationships between responses, we predicted older adults would show significantly less learning than young adults. Older adults demonstrated lower performance (slower reaction time and lower accuracy). However, contrary to our prediction, older adults showed similar rates of learning as indexed by a configural learning score compared to young adults. These results suggest that the ability to acquire knowledge incidentally about configural response relationships is largely unaffected by cognitive aging. The configural response learning task provides insight into the task demands that constrain learning abilities in older adults. 相似文献
15.
Cardiac deaths are more likely to be unanticipated than cancer deaths by patients, their families, and their physicians. We hypothesized that differing physician attitudes toward dying patients may affect the degree of expectation of death. To evaluate differences in attitudes and behaviors among subspecialists, we surveyed a randomly selected population of California subspecialists; 44 of 136 (32%) of cardiologists and 91 of 167 (55%) of oncologists responded. Oncologists experienced three times as many deaths as cardiologists and reported having discussed code status more often with patients who died. Cardiologists'' patients'' deaths were more often unexpected and occurred more frequently in intensive care units. In addition, their patients were more likely to be given cardiopulmonary resuscitation. Oncologists reported being more comfortable dealing with dying patients and having less desire to avoid them. When presented with patient scenarios, however, cardiologists'' and oncologists'' responses were similar when discussing and estimating prognosis and likelihood of successful therapy. 相似文献
16.
Unlike classical -1,4-galactosyltransferase (-1,4-GalT I), -1,4-GalT V (formerly IV*) has little activity towards 1 mM N-acetylglucosamine [Sato et al. (1998) Proc Natl Acad Sci USA 95: 472-477]. The human -1,4-GalTs I and V were expressed individually in Sf-9 cells by transfection of the full coding sequences, and their N-acetyllactosamine synthetase activities were determined towards different N-acetylglucosamine concentrations. Kinetic studies using the cell homogenates as an enzyme source revealed that -1,4-GalTs I and V possess Km values of 0.6 mM and 33 mM towards N-acetylglucosamine, and of 48 µM and 41 µM towards UDPGal, respectively. No significant inhibition of N-acetyllactosamine synthesis with -lactalbumin was observed for -1,4-GalT V but the significant inhibition with -lactalbumin was observed for -1,4-GalT I. 相似文献
17.
Daniel H. Baker 《PloS one》2013,8(7)
One of the primary objectives of early visual processing is the detection of luminance variations, often termed image contrast. Normal observers can differ in this ability by at least a factor of 4, yet this variation is typically overlooked, and has never been convincingly explained. This study uses two techniques to investigate the main source of individual variations in contrast sensitivity. First, a noise masking experiment assessed whether differences were due to the observer’s internal noise, or the efficiency with which they extracted information from the stimulus. Second, contrast discrimination functions from 18 previous studies were compared (pairwise, within studies) using a computational model to determine whether differences were due to internal noise or the low level gain properties of contrast transduction. Taken together, the evidence points to differences in contrast gain as being responsible for the majority of individual variation across the normal population. This result is compared with related findings in attention and amblyopia. 相似文献
18.
Rahel Schumacher Dario Cazzoli No?mi Eggenberger Basil Preisig Tobias Nef Thomas Nyffeler Klemens Gutbrod Jean-Marie Annoni René M. Müri 《PloS one》2015,10(11)
Purpose
We aimed at further elucidating whether aphasic patients’ difficulties in understanding non-canonical sentence structures, such as Passive or Object-Verb-Subject sentences, can be attributed to impaired morphosyntactic cue recognition, and to problems in integrating competing interpretations.Methods
A sentence-picture matching task with canonical and non-canonical spoken sentences was performed using concurrent eye tracking. Accuracy, reaction time, and eye tracking data (fixations) of 50 healthy subjects and 12 aphasic patients were analysed.Results
Patients showed increased error rates and reaction times, as well as delayed fixation preferences for target pictures in non-canonical sentences. Patients’ fixation patterns differed from healthy controls and revealed deficits in recognizing and immediately integrating morphosyntactic cues.Conclusion
Our study corroborates the notion that difficulties in understanding syntactically complex sentences are attributable to a processing deficit encompassing delayed and therefore impaired recognition and integration of cues, as well as increased competition between interpretations. 相似文献19.
Dr. Jeanick Brisswalter François Bieuzen Magali Giacomoni Véronique Tricot Guy Falgairette 《Chronobiology international》2013,30(3):495-506
This study analyzed diurnal variations in oxygen (O2) uptake kinetics and efficiency during a moderate cycle ergometer exercise. Fourteen physically active diurnally active male subjects (age 23±5 yrs) not specifically trained at cycling first completed a test to determine their ventilatory threshold (Tvent) and maximal oxygen consumption (VO2max); one week later, they completed four bouts of testing in the morning and evening in a random order, each separated by at least 24 h. For each period of the day (07:00–08:30 h and 19:00–20:30 h), subjects performed two bouts. Each bout was composed of a 5 min cycling exercise at 45 W, followed after 5 min rest by a 10 min cycling exercise at 80% of the power output associated with Tvent. Gas exchanges were analyzed breath‐by‐breath and fitted using a mono‐exponential function. During moderate exercise, the time constant and amplitude of VO2 kinetics were significantly higher in the morning compared to the evening. The net efficiency increased from the morning to evening (17.3±4 vs. 20.5±2%; p<0.05), and the variability of cycling cadence was greater during the morning than evening (+34%; p<0.05). These findings suggest that VO2 responses are affected by the time of day and could be related to variability in muscle activity pattern. 相似文献
20.
A methanol-utilizing phototrophic bacterium, strain M402, was isolated from surface water of an acidic hot spring. The isolated strain was identified as Rhodopseudomonas acidophila from its morphological and physiological characters. Profiles of the utilization of non-aromatic compounds as carbon sources by this strain were in good agreement with those of some strains of R. acidophila reported by Pfennig [J. Bacteriol., 99, 597 (1969)]. However, strain M402 was found to be capable of utilizing vanillic acid, vanillin, vanillyl alcohol, ferulic acid, veratric acid, syringic acid, syringal-dehyde and benzyl alcohol as carbon sources under anaerobic-light conditions. Although Pfennig did not refer to these abilities of his strains, these notable characters of strain M402 seem to be additional new characters of R. acidophila. 相似文献