共查询到20条相似文献,搜索用时 30 毫秒
1.
L. Cecchi T. Torrigiani Malaspina R. Albertini M. Zanca E. Ridolo I. Usberti M. Morabito P. Dall’ Aglio S. Orlandini 《Aerobiologia》2007,23(2):145-151
Ragweed is an allergenic weed of public health concern in several European countries. In Italy ragweed occurs prevalently
in north-north-eastern regions, where sensitization is increasing. Because of the small diameter of pollen grains, ragweed
pollen is often involved in episodes of long-range transport, as already shown in central Italy. The objective of this study
was to evaluate the extent of such transport by comparing pollen and meteorological data for two northern Italian cities (Parma
and Mantova) with data from Pistoia and Florence in central Italy. In 2002 and 2004 peaks in ragweed pollen levels were detected
in these four cities on the same day, and concentrations of the grains were above clinical thresholds. Weather-map analysis
and computation of back-trajectories showed that air masses from eastern Europe might carry ragweed pollen to a wide area
of central and northern Italy. These findings suggest that episodes of long-range transport of ragweed pollen could be clinically
relevant, resulting in sensitization of a large number of people. The results might provide a basis for monitoring and forecasting
periods of long-distance transport with the objective of reducing their effects on allergic patients. 相似文献
2.
About 30% of the Hungarian population has some type of allergy, 65% of them have pollen sensitivity, and at least 60% of this pollen sensitivity is caused by ragweed. The short (or common) ragweed (Ambrosia artemisiifolia = Ambrosia elatior) has the most aggressive pollen of all. Clinical investigations prove that its allergenic pollen is the main reason for the most massive, most serious and most long-lasting pollinosis. The air in the Carpathian Basin is the most polluted with ragweed pollen in Europe. The aim of the study is to analyse how ragweed pollen concentration is influenced by meteorological elements in a medium-sized city, Szeged, Southern Hungary. The data basis consists of daily ragweed pollen counts and averages of 11 meteorological parameters for the 5-year daily data set, between 1997 and 2001. The study considers some of the ragweed pollen characteristics for Szeged. Application of the Makra test indicates the same period for the highest pollen concentration as that established by the main pollination period. After performing factor analysis for the daily ragweed pollen counts and the 11 meteorological variables examined, four factors were retained that explain 84.4% of the total variance of the original 12 variables. Assessment of the daily pollen number was performed by multiple regression analysis and results based on deseasonalised and original data were compared. 相似文献
3.
I. Müller-Germann D. A. Pickersgill H. Paulsen B. Alberternst U. Pöschl J. Fröhlich-Nowoisky V. R. Després 《Aerobiologia》2017,33(4):493-506
Mugwort (Artemisia vulgaris) and ragweed (Ambrosia artemisiifolia) are highly allergenic Asteraceae. They often cause pollen allergies in late summer and fall. While mugwort is native to Europe, ragweed reached Europe as a neophyte from North America about 150 years ago and continued spreading ever since. To understand possible relationships between the spread of ragweed, its abundance in air, and to judge possible health risks for the public, we quantified ragweed DNA in inhalable fine as well as in coarse air particulate matter. Mugwort was chosen for comparison, as it is closely related to ragweed and grows in similar, though mainly not identical, habitats but is native to Germany. The DNA quantification was performed on atmospheric aerosol samples collected over a period of 5 years in central Europe. The DNA concentrations were highest during the characteristic pollination periods but varied greatly between different years. In the inhalable fine particle fraction, ragweed exceeds the mugwort DNA concentration fivefold, while the coarse particle fraction, bearing intact pollen grains, contains more mugwort than ragweed DNA. The higher allergenic potential of ragweed might be linked to the humidity or long-range transport-induced bursting of ragweed pollen into smaller allergenic particles, which may reach the lower airways and cause more intense allergic reactions. Airborne ragweed DNA was detected also outside the local pollination periods, which can be explained by atmospheric long-range transport. Back-trajectory analyses indicate that the air masses containing ragweed DNA during winter had originated in regions with milder climate and large ragweed populations (Southern France, Carpathian Basin). 相似文献
4.
Małgorzata Malkiewicz Kamilla Klaczak Anetta Drzeniecka-Osiadacz Justyna Krynicka Krzysztof Migała 《Aerobiologia》2014,30(1):13-23
The aim of the study was to characterise Artemisia pollen season types according to weather conditions in Wroc?aw (south-western Poland) in the years 2002–2011. Over the period analysed, the start date of the pollen season (determined by the 95 % method) ranged from 10 July 2002 to 28 July 2010. The start date of the pollen season can be determined by using Crop Heat Units (CHUs). During the period 2002–2011, the Artemisia pollen season started after the cumulative value of CHUs had reached 2,000–2,100 °C. The three distinguished types of Artemisia pollen season are best described by the frequency of weather types defined by the type of circulation, mean daily air temperature, and the occurrence of rain. The variation in these factors affected the dynamics of the pollen season. The noteworthy frequency of days with rain and high seasonal sum of precipitation totals as well as the dominance of cyclonic weather from the westerly direction had an impact on the extension of the pollen season. The meteorological factors that directly affect pollen release and transport primarily include air humidity, expressed as vapour pressure (r > 0.3, p < 0.01), temperature(r from 0.2 to 0.4, p < 0.01). The relationships between averaged meteorological data and daily pollen concentration were stronger (r > 0.5, p < 0.01). Based on the correlation analysis, the meteorological variables were selected and regression equations were established using stepwise backward regression analysis. 相似文献
5.
Mary Kay O'Rourke Ph. D. James Joseph Quackenboss M. S. Michael David Lebowitz Ph. D. 《Aerobiologia》1989,5(2):104-110
Summary We conducted this study during the early spring to demonstrate direct response between increases in atmospheric pollen concentrations
and symptom prevalence in a general population. We examined pollen concentrations indoors, outdoors and regionally in 31 households
with similar background vegetation, pollen concentration, TSP and pollulant gas levels. Indoor pollen concentrations were
low but persistent (X=16 grains/m3 air); local outdoor concentrations were 3 times greater. Regional daily mean pollen values of grasses, ragweed, mulberry
and total pollen were compared with symptom scores using X2 contingency tests. We obtained daily symptom scores and measures of peak expiratory flow from 121 individuals characterized
as ?normal?, ?atopic? or ?peak flow responsive?. In atopic individuals, prevalence of nasal symptoms increased with pollen
concentration increases for ragweed, mulberry and total pollen exposure. No significant response was found with spring grasses
whose atmospheric pollen concentration was limited in the selected cluster. Decrease of lung function in the peak flow responsive
population was found associated with mulberry pollen only. The small pollen grain size may result in greater tracheo-bronchial
deposition. 相似文献
6.
Pollen-related allergy is a common disease resulting in symptoms of hay fever and asthma. Control of symptoms depends (generally)
on avoidance and pharmacological treatment. Both of these approaches could benefit from accurate predictions of pollen levels
for future days. We have constructed a model that uses meteorological data to predict ragweed pollen levels based on air samples
collected daily in Kalamazoo, MI from 1991 to 1994. Ragweed pollen counts were converted to pollen grains/m3 of air (24-h average). We used Poisson regression, which appropriately handles the heterogenous variance associated with
pollen data. Using standard statistical model selection procedures, combined with biological considerations, we selected rainfall,
wind speed, temperature, and the time measured from the start of the season as the most significant variables. Using our model,
we propose a method that uses the weather forecast for the following day to predict the ragweed pollen level. This approach
differs from most previous attempts because it uses Poisson regression and because this model needs to be fit iteratively
each day. By updating the coefficients of the model based on the information to date, this method allows the fundamental shape
of the pollen distribution curve to change from year to year. Application to the Kalamazoo data suggests that the method has
good sensitivity and specificity for predicting high pollen days. 相似文献
7.
Małgorzata Puc 《Aerobiologia》2006,22(1):67-78
Ragweed (genus Ambrosia) and mugwort (Artemisia vulgaris) pollen grains are known to be very potent aeroallergens, often noted to enter into cross reactions. The aim of the study
was to analyse ragweed and mugwort pollen release in Szczecin (western Poland) during the period 2000–2003. Measurements were
performed by the volumetric and gravimetric method. Pollen seasons were defined as the periods of 90% of the total catch.
Of the 4 years studied, the lowest concentration of ragweed pollen was observed in 2000. In 2000, the annual ragweed pollen
count was very high, threefold higher than in 2001. There was a high Ambrosia pollen count in 2003, with the highest daily value of 84 grains/m3. The mugwort pollen season started in the third 10-day period of July and lasted to the end of August in all of the years
studied. Analysis of pollen deposition from different Szczecin city’s districts showed that the highest exposure to ragweed
pollen allergens occurred in the Majowe district, which is related to the presence of numerous plants of Ambrosia in that district. The mugwort pollen deposition was more abundant in the Żelechowa district, which is an area with villas
and gardens. Statistically significant correlations were found between the ragweed pollen count in the air and the maximum
wind speed, air temperature and relative humidity and between the mugwort pollen count in the air and air temperature and
relative humidity. 相似文献
8.
Zink K Vogel H Vogel B Magyar D Kottmeier C 《International journal of biometeorology》2012,56(4):669-680
Common ragweed (Ambrosia artemisiifolia L.) is a highly allergenic plant that is spreading throughout Europe. Ragweed pollen can be transported over large distances by the wind. Even low pollen concentrations of less than 10 pollen m(-3) can lead to health problems in sensitive persons. Therefore, forecasting the airborne concentrations of ragweed pollen is becoming more and more important for public health. The question remains whether distant pollen sources need to be considered in reliable forecasts. We used the extended numerical weather prediction system COSMO-ART to simulate the release and transport of ragweed pollen in central Europe. A pollen episode (September 12-16, 2006) in north-eastern Germany was modeled in order to find out where the pollen originated. For this purpose, several different source regions were taken into account and their individual impact on the daily mean pollen concentration and the performance of the forecast were studied with the means of a 2?×?2 contingency table and skill scores. It was found that the majority of the pollen originated in local areas, but up to 20% of the total pollen load came from distant sources in Hungary. It is concluded that long-distance transport should not be neglected when predicting pollen concentrations. 相似文献
9.
Maja Telišman Prtenjak Lidija Srnec Renata Peternel Valentina Madžarević Ivana Hrga Barbara Stjepanović 《International journal of biometeorology》2012,56(6):1145-1158
We examined the atmospheric conditions favourable to the occurrence of maximum concentrations of ragweed pollen with an extremely high risk of producing allergy. Over the 2002–2009 period, daily pollen data collected in Zagreb were used to identify two periods of high pollen concentration (> 600 grains/m3) for our analysis: period A (3–4 September 2002) and period B (6–7 September 2003). Synoptic conditions in both periods were very similar: Croatia was under the influence of a lower sector high pressure system moving slowly eastward over Eastern Europe. During the 2002–2009 period, this type of weather pattern (on ~ 70% of days), in conjunction with almost non-gradient surface pressure conditions in the area (on ~ 30% of days) characterised days when the daily pollen concentrations were higher than 400 grains/m3. Numerical experiments using a mesoscale model at fine resolution showed successful multi-day simulations reproducing the local topographic influence on wind flow and in reasonable agreement with available observations. According to the model, the relatively weak synoptic flow (predominantly from the eastern direction) allowed local thermal circulations to develop over Zagreb during both high pollen episodes. Two-hour pollen concentrations and 48-h back-trajectories indicated that regional-range transport of pollen grains from the central Pannonian Plain was the cause of the high pollen concentrations during period A. During period B, the north-westward regional-range transport in Zagreb was supplemented significantly by pronounced horizontal recirculation of pollen grains. This recirculation happened within the diurnal local circulation over the city, causing a late-evening increase in pollen concentration. 相似文献
10.
Trajectory analysis is a valuable tool that has been used before in aerobiological studies, to investigate the movement of airborne pollen. This study has employed back-trajectories to examine the four highest grass pollen episodes at Worcester, during the 2001 grass pollen season. The results have shown that the highest grass pollen counts of the 2001 season were reached when air masses arrived from a westerly direction. Back-trajectory analysis has a limited value to forecasters because the method is retrospective and cannot be employed directly for forecasting. However, when used in conjunction with meteorological data this technique can be used to examine high magnitude events in order to identify conditions that lead to high pollen counts. 相似文献
11.
The aim of this study was to determine the onset, length and end of the ragweed pollen season, taking into account diurnal, day-to-day, monthly and annual pollen variations, the effect of some meteorological parameters on atmospheric pollen concentrations and possible differences in the airborne pollen season and concentration due to sampling site. Airborne pollen was collected at three sites in central Croatia (Zagreb, Samobor and Ivanić Grad) during three pollen seasons (2002–2004). Seven-day Hirst-type volumetric pollen traps were used for pollen sampling. Ragweed pollen was the third most abundant pollen type to occur in the atmosphere of central Croatia. Total Ambrosia pollen concentration was the highest in the 2003 pollen season and the lowest in 2004 at all sampling sites. Maximum emissions were restricted to August and September. Intradiurnal periodicity showed a peak from 1000 to 1200 hours. The concentration of ragweed pollen during the pollen season was greatly influenced by temperature and precipitation: on rainy days accompanied by temperature decline, the air pollen concentration decreased abruptly. The results of this study are aimed at helping to alleviate the symptoms of allergic reactions in individuals with ragweed pollen hypersensitivity, thus improving their quality of life. 相似文献
12.
Ragweed pollen: The aeroallergen is spreading in Italy 总被引:1,自引:0,他引:1
Presently in Europe, ragweed pollen as an aeroallergen is not as important as Poaceae,Parietaria or Betulaceae, even if in some countries the plant is beginning to influence the local composition of the airborne pollen
spectra. In northern Italy, the presence of ragweed airborne pollen has only been reported since the beginning of the 1980’s
and it is increasingly spreading from year to year. Given this situation, the allergologists have begun to regard the potential
risk of sensitisation to ragweed pollen with much attention. Up to now, such pollen has not been included in the routine allergological
tests. In 1995 in some sites of northern Italy (Turin, Milan, Trieste), the concentration values of ragweed pollen were remarkable
(∼ 20–30 p/m3) and on the increase with respect to the previous years. This investigation aims at focusing the atmospheric concentration
trend on this new aeroallergen (Ambrosia sp.) in Italy from 1991 throughout 1995. 相似文献
13.
A comparison of external parasitic infestations among inhabitants of Legnica, Wa?brzych, and Wroc?aw districts, in the Lower Silesia region of Poland showed a direct relationship between the high incidence of scabies and low standard ecological indices, as well as social economic setting of the communities. In the years 1990-1997, the highest mean incidences of scabies per 100,000 people (80 and 46) were noted, respectively, in the Legnica and Wa?brzych districts, compared to only 7.9 in the Wroc?aw district. Infestation was correlated with percentages of the population with higher education (4.8; 4.2, 10.1, respectively) and the number of patients per physician (795, 632, 288, respectively), and the percentages of degraded land/and land threatened by degradation (10/37, 5/16, 0.7/10, respectively), forest stands damaged by gases and particulates (99.4, 99.4, 58.8, respectively), and air pollution emission indices in the towns of Legnica and Wa?brzych (30 and 21 tons/km2) and Wroc?aw (16). Scabies infestation was highest in children and teenagers (0-19) and was gender-associated (in all age groups, women were more often infested than men). A decreasing rate of scabies infestation, especially from the mid-1990s, was noted for both scabies and pediculosis in Wa?brzych district; in the 0-19-yr-old inhabitants, it varied from 0.75% in 1994 to 0.41% in 1996. 相似文献
14.
Time-varying parametric linear and time-varying nonparametric regression models as well as a time-varying nonparametric median
regression model are developed to predict the daily pollen concentration for Szeged in Hungary using previous-day meteorological
parameters and the daily pollen concentration. The models are applied to rainy days and non-rainy days, respectively. The
most important predictor is the previous-day pollen concentration level, and the only other predictor retained by a stepwise
regression procedure is the daily mean global solar flux for rainy days and the daily mean temperature for non-rainy days.
Although the variance percentage explained by these two predictors is higher for non-rainy (55.2%) days than for rainy (51.9%)
days, the prediction rate is slightly better for rainy than for non-rainy days. Nonparametric regression yields substantially
better estimates, especially for rainy days indicating a nonlinear relationship between the predictors and the pollen concentration.
The explained variance percentage is 71.4 and 64.6% for rainy and non-rainy days, respectively. Concerning the mean absolute
error, the nonparametric median regression provides the best estimate. The quantile regression shows that probability distribution
of daily ragweed concentration is much more skewed for non-rainy days, while the more concentrated probability distribution
for rainy days exhibits relatively stable ragweed pollen concentrations. The possible lowest limits of concentrations are
also calculated. Under highly favorable conditions for peak concentrations, the pollen level reaches at least 350 grains m−3 and 450 grains m−3 for rainy and non-rainy days, respectively. These values again underline the excessive ragweed pollen load over the area
of Szeged. 相似文献
15.
Identification of potential sources of airborne Olea pollen in the Southwest Iberian Peninsula 总被引:1,自引:0,他引:1
Santiago Fernández-Rodríguez Carsten Ambelas Skjøth Rafael Tormo-Molina Rui Brandao Elsa Caeiro Inmaculada Silva-Palacios Ángela Gonzalo-Garijo Matt Smith 《International journal of biometeorology》2014,58(3):337-348
This study aims to determine the potential origin of Olea pollen recorded in Badajoz in the Southwest of the Iberian Peninsula during 2009–2011. This was achieved using a combination of daily average and diurnal (hourly) airborne Olea pollen counts recorded at Badajoz (south-western Spain) and Évora (south-eastern Portugal), an inventory of olive groves in the studied area and air mass trajectory calculations computed using the HYSPLIT model. Examining olive pollen episodes at Badajoz that had distinctly different diurnal cycles in olive pollen in relation to the mean, allowed us to identify three different scenarios where olive pollen can be transported to the city from either distant or nearby sources during conditions with slow air mass movements. Back trajectory analysis showed that olive pollen can be transported to Badajoz from the West on prevailing winds, either directly or on slow moving air masses, and from high densities of olive groves situated to the Southeast (e.g. Andalucía). Regional scale transport of olive pollen can result in increased nighttime concentrations of this important aeroallergen. This could be particularly important in Mediterranean countries where people can be outdoors during this time due to climate and lifestyle. Such studies that examine sources and the atmospheric transport of pollen are valuable for allergy sufferers and health care professionals because the information can be incorporated into forecasts, the outputs of which are used for avoiding exposure to aeroallergens and planning medication. The results of studies of this nature can also be used for examining gene flow in this important agricultural crop. 相似文献
16.
Giuseppe Piazza Guglielmo Marco Migliorino Lucia Cassani Fabrizio Della Torre 《Aerobiologia》1992,8(1):27-30
Summary Since 1982 we have been monitoring allergological pollen, by means of a Lanzoni pollen trap VPPS 2000. In 1988 we detected the ragweed pollen for the first time, and subsequently in 1989 and in 1990.In 1988 it had been monitored from 16/8 to 26/9 (highest concentration 66.5 gr/m3/24 h on 3/9), in 1989 from 7/8 to 23/9 (highest concentration 30.0 gr/m3/24 h on 10/9) and in 1990 from 3/8 to 23/9 (highest concentration 80.9 gr/m3/24 h on 2/9). During the same years the prick test for ragweed pollen turned out to be positive in 27 patients out of 1526 (1.76%) in 1988, in 25 patients out of 1517 (1.64%) in 1989 and in 56 patients out of 1614 (3.41%) in 1990.The presence of specific IgE turned out to be positive in 12 patients out of 189 (6.35%) in 1988, in 17 patients out of 195 (8.71%) in 1989 and in 22 patients out of 230 (9.56%) in 1990.During out 3-years investigation, on the basis of the severity of symptoms and of the possible multi-sensitization, only 2 patients have undergone a specific immunotherapy to ragweed pollen.Our data confirm the presence of ragweed pollen in Lombardy, even if the sensitization is low in our population and the clinical significance of ragweed pollinosis is even lower.Nevertheless the high sensitizing power of this pollen makes a higher incidence of ragweed pollinosis possible in coming years. 相似文献
17.
Miguel A. Hernández-Ceballos Hermínia García-Mozo José Antonio Adame Eugenio Domínguez-Vilches Benito A. De la Morena Juan Pedro Bolívar Carmen Galán 《International journal of biometeorology》2011,55(1):17-34
The main goal of the present study was to provide a detailed analysis of olive pollen transport dynamics in the province of
Córdoba (south-western Spain) by applying back-trajectory analysis. Pollen data from 2006 and 2007 were analysed at four monitoring
sites: Córdoba city in the centre of the province, Baena and Priego de Córdoba located in the south, and El Cabril reserve
(Hornachuelos Natural Park) in the north. Particular attention was paid to nine episodes of high pollen counts. Synoptic surface
maps were used, and kinematic back-trajectories (3D) were computed using the hybrid single particle Lagrangian integrated
trajectory model (HYSPLIT) at 500 m above ground level, run with a time-step of 6 h over a period of 36 h. Findings were analysed
in conjunction with daily and bi-hourly airborne pollen data, field phenological data and hourly surface meteorological data
recorded at nearby stations: temperature, relative humidity, rainfall, wind direction and wind speed. The results identified
two pollen source areas over the Córdoba province, the largest one located in the south, affecting Baena, Priego de Córdoba
and Córdoba city, and one smaller located in the west, which determines mainly the pollen cycle over the north of the province,
El Cabril. In addition, two air mass circulations were found, one coming from the south and crossing the main olive pollen
sources very close to the surface and being frequently associated with higher pollen counts, and the other coming from the
west and, in the episodes investigated, influencing mainly the north of the province. 相似文献
18.
Ragweed in the Czech Republic 总被引:4,自引:0,他引:4
Ondřej Rybníček Bronislava Novotná Eliška Rybníčkova Kamil Rybníček 《Aerobiologia》2000,16(2):287-290
During the last years, a well documented expansion ofragweed (Ambrosia artemisiifolia L., Ambrosia trifida L.) over the Mediterranean andtemperate Europe has been in progress. The currentdistribution of ragweed plants in the Czech Republicis summarized and the ragweed pollen concentration asmonitored by 12 pollen stations in the country isdiscussed. The present situation in the ragweed pollensensitization among children and adults with pollenallergy in Brno is described. So far no dangerousexpansion of ragweed plants in our country has beenobserved. Ragweed pollen concentration is occasionallysignificant in the Brno station only, other pollenstations are reporting insignificant amounts ofragweed pollen during August-September periods,although there has been a steady increase in ragweedpollen concentration in the Prague area over the lastfive years. Skin prick tests and/or specific IgEmeasurements with ragweed allergen were performed on94 children with pollen allergy in the Brno region in1995 and on 206, 210 and 229 adult allergic patientsin 1995, 1996 and 1997, respectively. Positive skinreaction or positive specific IgE to ragweed was foundin 22% children and in 25% (1995), 19% (1996) and 25% (1997) adults with pollen allergy. It isconcluded that ragweed does not seem to represent anyimminent major threat to the allergic population inthe Czech Republic until now, however, it remains apotentially very dangerous allergen. 相似文献
19.
N Münevver PINAR 《植物学报(英文版)》2003,45(12)
The airborne ragweed pollen spectrum was investigated in the air of Ankara, Turkey for aperiod of ten years (1990-1999) using a Burkard seven-day volumetric recording trap. In our study period,long distance transported Ambrosia pollen has been registered. Daily pollen levels varied from low to highin Burge's system. In last three years, the pollen concentration of Ambrosia showed a clear increasingtendency. Our results prove that ragweed pollen may be an important threat for ragweed sensitive patientsin Ankara city in near future. 相似文献
20.
Common ragweed (Ambrosia artemisiifolia L.): allergenicity and molecular characterization of pollen after plant exposure to elevated NO2
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Feng Zhao Amr Elkelish Jörg Durner Christian Lindermayr J. Barbro Winkler Franziska Ruёff Heidrun Behrendt Claudia Traidl‐Hoffmann Andreas Holzinger Werner Kofler Paula Braun Christine von Toerne Stefanie M. Hauck Dieter Ernst Ulrike Frank 《Plant, cell & environment》2016,39(1):147-164
Ragweed pollen is the main cause of allergenic diseases in Northern America, and the weed has become a spreading neophyte in Europe. Climate change and air pollution are speculated to affect the allergenic potential of pollen. The objective of this study was to investigate the effects of NO2, a major air pollutant, under controlled conditions, on the allergenicity of ragweed pollen. Ragweed was exposed to different levels of NO2 throughout the entire growing season, and its pollen further analysed. Spectroscopic analysis showed increased outer cell wall polymers and decreased amounts of pectin. Proteome studies using two‐dimensional difference gel electrophoresis and liquid chromatography–tandem mass spectrometry indicated increased amounts of several Amb a 1 isoforms and of another allergen with great homology to enolase Hev b 9 from rubber tree. Analysis of protein S‐nitrosylation identified nitrosylated proteins in pollen from both conditions, including Amb a 1 isoforms. However, elevated NO2 significantly enhanced the overall nitrosylation. Finally, we demonstrated increased overall pollen allergenicity by immunoblotting using ragweed antisera, showing a significantly higher allergenicity for Amb a 1. The data highlight a direct influence of elevated NO2 on the increased allergenicity of ragweed pollen and a direct correlation with an increased risk for human health. 相似文献