共查询到20条相似文献,搜索用时 500 毫秒
1.
2.
3.
4.
5.
Tom Maniatis Mark Ptashne Keith Backman Dennis Kleid Stuart Flashman Andrea Jeffrey Russell Maurer 《Cell》1975,5(2):109-113
Nucleotide sequences in two wild-type and six mutant operators in the DNA of phage λ are compared. Strikingly similar 17 base pair units are found which we identify as the repressor binding sites. Each operator contains multiple repressor binding sites separated by A-T rich spacers. Elements of 2 fold rotational symmetry are present in each of the sites. Superimposed on each operator is an E. coli RNA polymerase recognition site (promoter). Similarities in the sequences of the two λ promoters, a lac promoter, and an E. coli RNA polymerase recognition site in SV40 DNA are noted. 相似文献
6.
7.
8.
9.
10.
11.
12.
13.
Bidirectional transcription footprinting of DNA binding ligands 总被引:1,自引:0,他引:1
14.
15.
16.
17.
18.
19.
20.