共查询到20条相似文献,搜索用时 15 毫秒
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O P Singh B Bj?rkroth S Masich L Wieslander B Daneholt 《Experimental cell research》1999,251(1):135-146
Specific premessenger ribonucleoprotein (pre-mRNP) particles, the Balbiani ring (BR) granules in the salivary glands of the dipteran Chironomus tentans, can be visualized in the electron microscope when they assemble on the genes, move through nucleoplasm, and bind to and translocate through the nuclear pores. As shown by BrUTP labeling and immunoelectron microscopy, newly synthesized BR RNP particles, released from the BR genes, appear early in all nucleoplasmic regions of the cell nucleus and they saturate the nucleoplasmic pool of BR particles after 2 h of labelling. It is concluded that within the nucleus the BR particles move randomly. Furthermore, estimates of minimum diffusion coefficients for the BR particles are compatible with the view that the particles diffuse freely in the interchromosomal space, although it is not excluded that the random movement could be slightly retarded. Once the particles get bound to the nuclear pore complexes, they seem committed to translocation through the nuclear pores. 相似文献
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The hrp23 Protein in the Balbiani Ring Pre-mRNP Particles Is Released Just before or at the Binding of the Particles to the Nuclear Pore Complex 总被引:5,自引:2,他引:3
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Xin Sun Alla T. Alzhanova-Ericsson Neus Visa Youssef Aissouni Jian Zhao Bertil Daneholt 《The Journal of cell biology》1998,142(5):1181-1193
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Packing and delivery of a genetic message 总被引:1,自引:0,他引:1
Daneholt B 《Chromosoma》2001,110(3):173-185
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Architecture and anatomy of the genomic locus encoding the human leukemia-associated transcription factor RUNX1/AML1 总被引:5,自引:0,他引:5
Levanon D Glusman G Bangsow T Ben-Asher E Male DA Avidan N Bangsow C Hattori M Taylor TD Taudien S Blechschmidt K Shimizu N Rosenthal A Sakaki Y Lancet D Groner Y 《Gene》2001,262(1-2):23-33
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