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Transcriptional control of adipocyte formation 总被引:3,自引:0,他引:3
Farmer SR 《Cell metabolism》2006,4(4):263-273
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Jing Yang Siyuan Chen Yanfei Yang Xuelei Ma Bin Shao Shengyong Yang Yuquan Wei Xiawei Wei 《Cell proliferation》2020,53(2)
The jumonji domain‐containing protein 6 (JMJD6) is a Fe(II)‐ and 2‐oxoglutarate (2OG)‐dependent oxygenase that catalyses lysine hydroxylation and arginine demethylation of histone and non‐histone peptides. Recently, the intrinsic tyrosine kinase activity of JMJD6 has also been reported. The JMJD6 has been implicated in embryonic development, cellular proliferation and migration, self‐tolerance induction in the thymus, and adipocyte differentiation. Not surprisingly, abnormal expression of JMJD6 may contribute to the development of many diseases, such as neuropathic pain, foot‐and‐mouth disease, gestational diabetes mellitus, hepatitis C and various types of cancer. In the present review, we summarized the structure and functions of JMJD6, with particular emphasis on the role of JMJD6 in cancer progression. 相似文献
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Transcriptional control of chondrocyte fate and differentiation 总被引:10,自引:0,他引:10
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Transcriptional repression of pref-1 by glucocorticoids promotes 3T3-L1 adipocyte differentiation 总被引:10,自引:0,他引:10
Smas CM Chen L Zhao L Latasa MJ Sul HS 《The Journal of biological chemistry》1999,274(18):12632-12641