Synaptic asymmetry to go

Cell polarity is critical for T lymphocyte movement during their hunt for antigen-bearing cells and for infected target cells. In this issue of Cell, Yeh et al. (2008) now reveal a direct link between T cell polarity and the production of proinflammatory cytokines in mice lacking the class I MHC-restricted T cell-associated molecule (Crtam).     

Cytokinesis: cells go back and forth about division

An elegant quantitative model to explain cellular oscillations during cytokinesis reveals a novel function for polar blebbing and raises the question as to why cells live right on the edge.