Structure and engineering of the minimal type VI CRISPR-Cas13bt3

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Structure of the enterococcal T4SS protein PrgL reveals unique dimerization interface in the VirB8 protein family

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Molecular basis for anti-insomnia drug design from structure of lemborexant-bound orexin 2 receptor

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An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis

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Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site

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High-resolution mapping of metal ions reveals principles of surface layer assembly in Caulobacter crescentus cells

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Structural and functional insights into the mechanism by which MutS2 recognizes a DNA junction

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A set of closely related methyltransferases for site-specific tailoring of anthraquinone pigments

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TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation

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Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7–11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9

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The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone

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Structural and functional characterization of the N-terminal acetyltransferase Naa50

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Structural and dynamic effects of paraoxon binding to human acetylcholinesterase by X-ray crystallography and inelastic neutron scattering

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Structural Basis for Glycerol Efflux and Selectivity of Human Aquaporin 7

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The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral Target

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Unique Structural Features of Mammalian NEIL2 DNA Glycosylase Prime Its Activity for Diverse DNA Substrates and Environments

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Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain

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Extracellular Fe(III) reductase structure reveals a modular organization enabling S-layer insertion and electron transfer to insoluble substrates

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Structure-guided design of a perampanel-derived pharmacophore targeting the SARS-CoV-2 main protease

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A key GPCR phosphorylation motif discovered in arrestin2⋅CCR5 phosphopeptide complexes

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