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1.
Priyanka James Vipin Anithottam Mathai Silpa Shajikumar Priya Antony Pereppadan Parvathi Sudha Raghunath Keshavachandran Puthiyaveetil Abdulla Nazeem 《Bioinformation》2013,9(18):941-943
Medicinal plants and plant derived molecules are widely used in traditional cultures all over the world and they are becoming
large popular among biomedical researchers and pharmaceutical companies as a natural alternative to synthetic medicine.
Information related to medicinal plants and herbal drugs accumulated over the ages are scattered and unstructured which make it
prudent to develop a curated database for medicinal plants. The Antidiabetic and Anticancer Medicinal Plants Database
(DIACAN) aims to collect and provide an integrated platform for plants and phytochemiclas having antidiabetic or anticancer activity.
Availability
http://www.kaubic.in/diacan 相似文献2.
Drug development from natural sources is an important and fast developing area. Natural sources (plants) have been used to cure
a range of diseases for Thousands of years. Different online medicinal plant databases provide information about classifications,
activities, phytochemicals and structure of phytochemicals in different formats. These databases do not cover all aspects of
medicinal plants. MAPS (Medicinal plant Activities, Phytochemicals & structural database) has been constructed with uniqueness
that it combines all information in one web resource and additionally provides test targets on which particular plant found to be
effective with reference to the original paper as well. MAPS database is user friendly information resource, including the data of >
500 medicinal plants. This database includes phytochemical constituents, their structure in mol format, different activities
possessed by the medicinal plant with the targets reported in literature.
Availability
http://www.mapsdatabase.com 相似文献3.
Kumudini Tota Nihar Rayabarapu Sowmya Moosa Venu Talla Balaji Bhyravbhatla Srinivasa Rao 《Bioinformation》2013,9(7):378-380
According to International Diabetes Federation (IDF), India has 62.4 million people with diabetes and by 2030 it is predicted that
the number will rise to 100 million. Studies claim that there are around 410 experimentally proven Indian medicinal plants which
have anti-diabetic activity, of which the mechanism of action of 109 plants has been elucidated or reported. So, the need of the hour
is to explore the claims of Indian medicinal flora and open up the facets of many Indian plants which are being examined for their
beneficial role in diabetes. So, we created a database (InDiaMed) of Indian medicinal plants that captures their role in anti-diabetic
activity. InDiaMed''s features include chemical, pharmacological, biochemical and geographical information of the medicinal plant,
scientifically relevant information of the plant, and the coherent research done on it in the field of diabetes. The database also
includes the list of poly-herbal formulations which are used for treatment of diabetes in India.
Availability
http://www.indiamed.info 相似文献4.
Sushil Kumar Middha Yashoda Mittal Talembedu Ushal Dharmendra Kumar Ranjani Srinivasan Laxmikant Vashisth Biplab Bhattacahrgae Madhugiri Bhojangarao Nagaveni 《Bioinformation》2009,4(2):78-79
Herbs are the base used for treatment in Ayurveda. We describe a database named Phyto-Mellitus with information on plants traditionally used
for diabetes with their chemical constituents. The active principles of these plants are antioxidant and free radical scavenging.
Availability
http://www.bicmlacw.org/bt/ 相似文献5.
ChangKug Kim SooJin Kwon GangSeob Lee HwanKi Lee JiWeon Choi YongHwan Kim JangHo Hahn 《Bioinformation》2009,3(8):344-345
The AllergenPro database has developed a web-based system that will provide information about allergen in microbes, animals and plants. The database has three major parts and
functions:(i) database list; (ii) allergen search; and (iii) allergenicity prediction. The database contains 2,434 allergens related information readily available in the database
such as on allergens in rice microbes (712 records), animals (617 records) and plants (1,105 records). Furthermore, this database provides bioinformatics tools for allergenicity
prediction. Users can search for specific allergens by various methods and can run tools for allergenicity prediction using three different methods.
Availability
The database is available for free at http://www.niab.go.kr/nabic/ 相似文献6.
Maria Pratheepa Sushil Kumar Jalali Robinson Silvester Arokiaraj Thiruvengadam Venkatesan Mandadi Nagesh Madhusmita Panda Sharath Pattar 《Bioinformation》2014,10(2):98-100
Insect Barcode Information System called as Insect Barcode Informática (IBIn) is an online database resource developed by the
National Bureau of Agriculturally Important Insects, Bangalore. This database provides acquisition, storage, analysis and
publication of DNA barcode records of agriculturally important insects, for researchers specifically in India and other countries. It
bridges a gap in bioinformatics by integrating molecular, morphological and distribution details of agriculturally important insects.
IBIn was developed using PHP/My SQL by using relational database management concept. This database is based on the client–
server architecture, where many clients can access data simultaneously. IBIn is freely available on-line and is user-friendly. IBIn
allows the registered users to input new information, search and view information related to DNA barcode of agriculturally
important insects.This paper provides a current status of insect barcode in India and brief introduction about the database IBIn.
Availability
http://www.nabg-nbaii.res.in/barcode 相似文献7.
Shanmugam Anandakumar Saravanan Vijayakumar Nagarajan Arumugam M Michael Gromiha 《Bioinformation》2015,11(11):512-513
Mammalian Mitochondrial ncRNA is a web-based database, which provides specific information on non-coding RNA in mammals.
This database includes easy searching, comparing with BLAST and retrieving information on predicted structure and its function
about mammalian ncRNAs.
Availability
The database is available for free at http://www.iitm.ac.in/bioinfo/mmndb/ 相似文献8.
Chang Kug Kim Jung Sun Kim Gang Seob Lee Beom Seok Park Jang Ho Hahn 《Bioinformation》2008,3(2):61-62
The Plant Genetic Map Database (PlantGM) has been developed as a web-based system which provides information about genetic
markers in rice (Oryza sativa) and Chinese cabbage (Brassica rapa). The database has three major parts and functions;
(1) Map Search, (2) Marker Search, and (3) QTL Search. At present, the database provides characterization information for
about 3258 genetic markers. It has 2800 RFLP and 112 QTL markers related to rice in addition to 321 RFLP and 25 PCR-based
markers for Chinese cabbage. In addition, a genetic linkage map was also constructed by using 1,054 markers from 2,912
markers in rice.
Availability
The database is available for free at http://www.niab.go.kr/nabic/PlantGM 相似文献9.
10.
Chang-Kug Kim Young-Joo Seol Dong-Jun Lee In-Seon Jeong Ung-Han Yoon Gang-Seob Lee Jang-Ho Hahn Dong-Suk Park 《Bioinformation》2013,9(17):887-888
In 2013, National Agricultural Biotechnology Information Center (NABIC) reconstructs a molecular marker
database for useful genetic resources. The web-based marker database consists of three major functional categories:
map viewer, RSN marker and gene annotation. It provides 7250 marker locations, 3301 RSN marker property, 3280
molecular marker annotation information in agricultural plants. The individual molecular marker provides
information such as marker name, expressed sequence tag number, gene definition and general marker information.
This updated marker-based database provides useful information through a user-friendly web interface that assisted
in tracing any new structures of the chromosomes and gene positional functions using specific molecular markers.
Availability
The database is available for free at http://nabic.rda.go.kr/gere/rice/molecularMarkers/ 相似文献11.
Chang-Kug Kim Young-Joo Seol Dong-Jun Lee In-Seon Jeong Ung-Han Yoon Jong-Yeol Lee Gang-Seob Lee Dong-Suk Park 《Bioinformation》2014,10(6):378-380
The National Agricultural Biotechnology Information Center (NABIC) reconstructed an AllergenPro database for allergenic
proteins analysis and allergenicity prediction. The AllergenPro is an integrated web-based system providing information about
allergen in foods, microorganisms, animals and plants. The allergen database has the three main features namely, (1) allergen list
with epitopes, (2) searching of allergen using keyword, and (3) methods for allergenicity prediction. This updated AllergenPro
outputs the search based allergen information through a user-friendly web interface, and users can run tools for allergenicity
prediction using three different methods namely, (1) FAO/WHO, (2) motif-based and (3) epitope-based methods.
Availability
The database is available for free at http://nabic.rda.go.kr/allergen/ 相似文献12.
Diabetes, a chronic disease debilitating to normal healthy lifestyle, onsets due to insufficient amount of insulin production or
ineffective utilization of the amount produced. Although, pharmaceutical research has brought up remedial drugs and numerous
candidates in various phases of clinical trials, off-target effects and unwanted physiological actions are a constant source of concern
and contra indicatory in case of diabetic patients. Here we present a phytoremedial database, Phyto Diab Care, broadly applicable
to any known anti-diabetic medicinal plant and phytochemicals sourced from them. Utilization of the traditional medicine
knowledge for combating diabetes without creating unwanted physiological actions is our major emphasis. Data collected from
peer-reviewed publications and phytochemicals were added to the customizable database by means of an extended relational
design. The strength of this resource is in providing rapid retrieval of data from large volumes of text at a high degree of accuracy.
Enhanced web interface allows multi-criteria based information filtering. Furthermore, the availability of 2D and 3D structures
from molecular docking studies with any efficacy on the insulin signaling pathway makes the resource searchable and comparable
in an intuitive manner. Phyto Diab Care compendium is publicly available and can be found in online.
Availability
http://www.gbpuat-cbsh.ac.in/departments/bi/database/phytodiabcare/HOME%20PAGE/Home%20page.html 相似文献13.
Background
Linkage studies often yield intervals containing several hundred positional candidate genes. Different manual or automatic approaches exist for the determination of the gene most likely to cause the disease. While the manual search is very flexible and takes advantage of the researchers'' background knowledge and intuition, it may be very cumbersome to collect and study the relevant data. Automatic solutions on the other hand usually focus on certain models, remain “black boxes” and do not offer the same degree of flexibility.Methodology
We have developed a web-based application that combines the advantages of both approaches. Information from various data sources such as gene-phenotype associations, gene expression patterns and protein-protein interactions was integrated into a central database. Researchers can select which information for the genes within a candidate interval or for single genes shall be displayed. Genes can also interactively be filtered, sorted and prioritised according to criteria derived from the background knowledge and preconception of the disease under scrutiny.Conclusions
GeneDistiller provides knowledge-driven, fully interactive and intuitive access to multiple data sources. It displays maximum relevant information, while saving the user from drowning in the flood of data. A typical query takes less than two seconds, thus allowing an interactive and explorative approach to the hunt for the candidate gene.Access
GeneDistiller can be freely accessed at http://www.genedistiller.org 相似文献14.
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Padavala Ajay Babu Suma Sree Puppala Satyavarapu Lakshmi Aswini Metta Ramya Vani Chinta Narasimha Kumar Tallapragada Prasanna 《Bioinformation》2008,3(3):142-143
Marine compound database consists of marine natural products and chemical entities, collected from various literature sources,
which are known to possess bioactivity against human diseases. The database is constructed using html code. The 12 categories
of 182 compounds are provided with the source, compound name, 2-dimensional structure, bioactivity and clinical trial
information. The database is freely available online and can be accessed at
http://www.progenebio.in/mcdb/index.htm 相似文献
18.
Petros Kountouris Carsten W. Lederer Pavlos Fanis Xenia Feleki John Old Marina Kleanthous 《PloS one》2014,9(7)
Inherited haemoglobinopathies are the most common monogenic diseases, with millions of carriers and patients worldwide. At present, we know several hundred disease-causing mutations on the globin gene clusters, in addition to numerous clinically important trans-acting disease modifiers encoded elsewhere and a multitude of polymorphisms with relevance for advanced diagnostic approaches. Moreover, new disease-linked variations are discovered every year that are not included in traditional and often functionally limited locus-specific databases. This paper presents IthaGenes, a new interactive database of haemoglobin variations, which stores information about genes and variations affecting haemoglobin disorders. In addition, IthaGenes organises phenotype, relevant publications and external links, while embedding the NCBI Sequence Viewer for graphical representation of each variation. Finally, IthaGenes is integrated with the companion tool IthaMaps for the display of corresponding epidemiological data on distribution maps. IthaGenes is incorporated in the ITHANET community portal and is free and publicly available at http://www.ithanet.eu/db/ithagenes. 相似文献
19.
Wheat, the major source of vegetable protein in human diet, provides staple food globally for a large proportion of the human
population. With higher protein content than other major cereals, wheat has great socio- economic importance. Nonetheless for
wheat, three important fungal pathogens i.e. rust, smut and bunt are major cause of significant yield losses throughout the world.
Researchers are putting up a strong fight against devastating wheat pathogens, and have made progress in tracking and controlling
disease outbreaks from East Africa to South Asia. The aim of the present work hence was to develop a fungal pathogens database
dedicated to wheat, gathering information about different pathogen species and linking them to their biological classification,
distribution and control. Towards this end, we developed an open access database Tripath: A biological, genetic and genomic
database of economically important wheat fungal pathogens – rust: smut: bunt. Data collected from peer-reviewed publications
and fungal pathogens were added to the customizable database through an extended relational design. The strength of this
resource is in providing rapid retrieval of information from large volumes of text at a high degree of accuracy. Database TRIPATH
is freely accessible.
Availability
http://www.gbpuat-cbsh.ac.in/departments/bi/database/tripath/ 相似文献20.
A database providing information on mosquito specimens (Arthropoda: Diptera: Culicidae) collected in French Guiana is presented. Field collections were initiated in 2013 under the auspices of the CEnter for the study of Biodiversity in Amazonia (CEBA: http://www.labexceba.fr/en/). This study is part of an ongoing process aiming to understand the distribution of mosquitoes, including vector species, across French Guiana. Occurrences are recorded after each collecting trip in a database managed by the laboratory Evolution et Diversité Biologique
(EDB), Toulouse, France. The dataset is updated monthly and is available online. Voucher specimens and their associated DNA are stored at the laboratory Ecologie des Forêts de Guyane
(Ecofog), Kourou, French Guiana. The latest version of the dataset is accessible through EDB’s Integrated Publication Toolkit at http://130.120.204.55:8080/ipt/resource.do?r=mosquitoes_of_french_guiana or through the Global Biodiversity Information Facility data portal at http://www.gbif.org/dataset/5a8aa2ad-261c-4f61-a98e-26dd752fe1c5 It can also be viewed through the Guyanensis platform at http://guyanensis.ups-tlse.fr 相似文献