Mutations from patients with IPEX ported to mice reveal different patterns of FoxP3 and Treg dysfunction

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Autoimmune alleles at the major histocompatibility locus modify melanoma susceptibility

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Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

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A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13

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Human Fc Receptor-like 3 Inhibits Regulatory T Cell Function and Binds Secretory IgA

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Apoptotic cell fragments locally activate tingible body macrophages in the germinal center

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Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs

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The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands

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A purine metabolic checkpoint that prevents autoimmunity and autoinflammation

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SLC15A4 controls endolysosomal TLR7–9 responses by recruiting the innate immune adaptor TASL

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Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function

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Mitochondrial Oxidative Phosphorylation Regulates the Fate Decision between Pathogenic Th17 and Regulatory T Cells

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Follicular regulatory T cells produce neuritin to regulate B cells

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Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity

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Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma

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Thymic epithelial cells co-opt lineage-defining transcription factors to eliminate autoreactive T cells

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A scaling law in CRISPR repertoire sizes arises from the avoidance of autoimmunity

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Functional characterization of the dural sinuses as a neuroimmune interface

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Cold exposure protects from neuroinflammation through immunologic reprogramming

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Lung injury induces a polarized immune response by self-antigen-specific CD4+ Foxp3+ regulatory T cells

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