龙眼独活中的一个新二萜成分

从四川产木属 (Aralia)草本植物龙眼独活 (AraliafargesiiFranch .)根茎的石油醚提取部分分离得到 4个二萜化合物 ,根据理化性质测定和各种光谱 (IR、EI_MS、HREI_MS、1H NMR、13 C_NMR和HMQC)数据分析 ,它们的结构分别鉴定为 17_acetoxy_16α_ent_kauran_19_oicacid (1) ,ent_pimara_8(14) ,15_dien_19_oicacid (2 ) ,16α_hydroxy_(- )_kauran_19_oicacid (3)和 16α_17_dihydroxy_ent_kauran_19_oicacid (4 )。化合物 1为新化合物 ,3为首次从该属植物中分离得到 ,2～ 4为首次从龙眼独活中分离得到     

蕨类植物里白中一个新的对映- 贝壳杉烷型二萜化合物

从蕨类植物里白( Hicriopteris glauca) 的丙酮提取物中分离得到10 个化合物, 包括一个新的对映-贝壳杉烷型二萜化合物, 其化学结构通过各种波谱学方法鉴定为ent-2-β-hydroxyl-16-ene-kauran-19-oic acid(1)。     

蕨类植物里白中一个新的对映-贝壳杉烷型二萜化合物

从蕨类植物里白（Hicriopteris glauca）的丙酮提取物中分离得到10个化合物,包括一个新的对映-贝壳杉烷型二萜化合物,其化学结构通过各种波谱学方法鉴定为ent-2-β-hydroxyl-16-ene-kaurdn-19-oic acid （1）。     

思茅松松香中的一个新二萜

从思茅松（Pinus kesiya var.langbianensis）的松香中分离得到一个新奇的松香烷二萜化合物——思茅松素,经现代波谱分析将其化学结构确定为13（14）-烯-8,12-环氧-1-松香酸（1）,同时分离得到5个已知化合物,分别为abiet-8,11,13-trien-15-hydroxy-18-oic acid（2）;pimarol（3a）;iso-pimarol（3b）;abiet-trien-18．oic acid（4）;15．hydroxy abietic acid（5）。     

三褶脉紫菀中的新二萜甙

三褶脉紫菀（ＡｓｔｅｒａｇｅｒａｔｏｉｄｅｓＴｕｒｃｚ．）系菊科多年生草本植物,遍布全国,是民间常用的中药,有清热解毒、祛痰镇咳的功效［１,２］。化学工作者们曾从其同属植物紫菀（ＡｓｔｅｒｔａｒａｒｉｃｕｓＬ．ｆ．）中分离到紫菀酮（ｓｈｉｏｎｏｎｅ）、槲皮素（ｑｕｅｒｃｅｔｉｎ）、无羁萜（ｆｒｉｅｄｅｌｉｎ）、表无羁萜（ｅｐｉｆｒｉｅｄｅｌｉｎｅｌ）、毛叶醇（ｌａｃｈｎｏｐｈｙｌｌｏｌ）、乙酸毛叶酯（ｌａｃｈｎｏｐｈｙｌｌｏｌａｃｅｔａｔｅ）、茴香醚（ａｎｅｔｈｏｌｅ）以及紫菀三萜皂甙［２—４］…     

毛萼香茶菜中的一个新二萜

从毛萼香茶菜中分得8个二萜,3-乙酰毛萼结晶S、毛萼结晶甲、毛萼结晶乙、毛萼结晶丙、毛萼结晶丁、trichrokaurin、edonicin和eriocalyxin B。其中3-乙酰毛萼结晶S为新的对映-贝壳杉烷型二萜。由波谱法确定其结构。     

滇姜花中的新二萜成分-滇姜花戊素

从滇姜花根茎中分离到１个新二萜成分,命名为滇姜花戊素（１）,其结构经波谱学方法鉴定为１３β－ｆｕｒａｎｏｌａｂｄａ－８（１７）,１１－ｄｉｅｎ－６β,７α－ｄｉｏｌ。     

滇姜花中的新二萜成分--滇姜花素D

从滇姜花Ｈｅｄｙｃｈｉｕｍｙｕｎｎａｎｅｎｓｅ根茎中分离到３个二萜成分,分别为滇姜花Ｄ（１）,圆瓣姜花素Ａ（２）和ｈｅｄｙｃｈｅｎｏｎｅ（３）,（１）为新化合物,其结构经波谱学方法鉴定为１３β－ｆｕｒａｎｏｌａｂｄａ－６－ｏｘｏ－７,１１－ｄｉｅｎ－１７－ｏｌ。     

展毛短柄乌头中的一个新二萜生物碱

从展毛短柄乌头(Aconitum brachypodum var.laxiflorum Fletcher et Lauener)根中分离鉴定了五个二萜生物碱,其中四个为已知成分,分别为乌头碱(aconitine)、3-去氧乌头碱(3-deoxyaconitine)、3-乙酰乌头碱(3-acetylaconitine)、雪乌碱(penduline),另一个为新成分,命名为丽鲁碱(laxiconitine),其结构通过光谱分析及化学反应测定如(1)。     

星花绣线菊中的一个新二萜——绣线菊内酯B

从星花绣线菊（Ｓｐｉｒａｅａｊａｐｏｎｉｃａｖａｒ．ｓｔｅｌｌａｒｉｓ）根中得到１个新的Ａｔｉｓｉｎｅ型二萜,命名为绣线菊内酯Ｂ（１）。通过光谱分析测定了其结构,此外还得到了９个已知化合物,包括１个ａｔｉｓｉｎｅ型二萜－ｓｐｉｒａｍｉｎｏｌ（２）和８个二萜生物碱,ｓｐｉｒａｍｉｎｅＡ,Ｂ,Ｃ,Ｄ,Ｆ,Ｈ,Ｐ,Ｑ。     

半枝莲的一个新的克罗烷二萜

从半枝莲（Scutellaria barbara）植物地上部分的甲醇提取物中分离得到一个新的克罗烷二萜。通过现代波谱技术鉴定为15β-甲氧基-6α-O-乙酰基-19-O-丙酰基-4α,18;11,16;15,16-环氧-新克罗烷二萜。     

湖南参属的归并及亚洲楤木属(五加科)的一个新种和一些名称的变更

分子与形态证据表明湖南参 (HunaniopanaxhypoglaucusC .J.Qi&T .R .Cao)起源于木属 (AraliaL .) ,湖南参的近缘种为寄生五叶参 (Araliaparasitica)和轮伞五叶参 (Araliaverticillata) ,形态证据支持湖南参为轮伞五叶参的姐妹种 ,此 2种具轮伞花序这一共衍征。为了保证木属的单系性 ,现将湖南参并入木属 ,并作如下新组合 :Araliahypoglauca (C .J .Qi&T .R .Cao)J.Wen&Y .F .Deng .本文报道了湖南参在广西的新分布。目前的形态学和分子数据均不支持早先提出的湖南参与树参属 (Dendropanax)的近缘关系。本文亦报道了木属的 1新种、 2新种组合和 1个新名称 :AraliashangianaJ .Wen .sp .nov .(向氏五叶参 ,新种 ) ;Araliaglabrifoliolata (C .B .Shang)J .Wen .comb .nov . (光叶五叶参 ,新组合 ) ;Araliastellata (King)J.Wen ,comb .nov . (星毛羽叶参 ,新组合 )和AraliadelavayiJ .Wen .nom .nov .(云南五叶参 ,新名称 )。     

球药隔重楼的化学成分研究(英文)

采用硅胶柱层析、大孔吸附树脂、ODS柱层析、Sephadex LH-20和RP-C18柱层析等技术中分离得到8个化合物。通过波谱学数据和已知化合物数据比较,分别鉴定为β-谷甾醇(1),β-蜕皮激素(2),Paris SaponinsⅤ(3),Paris SaponinsⅠ(4),Paris SaponinsⅡ(5),Paris SaponinsⅦ(6),Paris Saponins H(7)和Paris SaponinsⅥ(8)。化合物1～8均为首次从球药隔重楼中分离得到。     

多根乌头中二萜生物碱成分

为研究多根乌头(AconitumkarakolicumRapaics)中二萜生物碱成分,本研究采用正反相硅胶柱和高效液相等色谱分离方法,从中分离得到15个二萜生物碱;通过多种波谱手段以及文献对比的方法鉴定其结构分别为aconitine(1),3-deoxyaconitine(2),16-epipyroaconine(3),neoline(4),indaconitine(5),14-benzoyl-8-O-methylaconitine(6),spicatineA(7),15-α-hydroxyneoline(8),taurenine(9),14-benzoylaconine(10),14-benzoylaconine-8-oleate(11),lappaconitine(12),beiwudine(13),13-hydroxyfranchetine(14)和8-O-linoleoyl-14-benzoylaconine(15),化合物3~15为首次从该植物中分离得到。采用MTT法和叶碟法分别考察了部分化合物的抗肿瘤和拒食活性,化合物14-benzoylaconine-8-oleate(11)对人乳腺癌MCF-7细胞、人肺癌H460细胞、肝癌HepG2细胞的IC50值分别为11.9、27.6和31.8μM。乌头碱型的二萜生物碱aconitine(1)、3-deoxyaconitine(2)、indaconitine(5)和beiwudine(13)表现出一定的拒食活性的活性(EC50<2mg/cm^2)。     

A New Pimarane Diterpenoid from the Botryotinia fuckeliana Fungus Isolated from Deep‐Sea Water

A new pimarane diterpenoid, named botryopimarene A ( 1 ), was discovered from the fungus Botryotinia fuckeliana MCCC 3 A00494 isolated from the deep‐sea water, together with ten known compounds. The planar structure of 1 was established based on the extensive spectroscopic analyses. The absolute configurations of tricyclic system in 1 were resolved by the theoretical ECD calculation, while the 15,16‐diol moiety in the side chain was resolved by the Mo₂(OAc)₄‐induced ECD spectrum. Compound 1 , featuring a Δ⁹⁽¹¹⁾ double bond, was rarely discovered in pimarane family. Compounds 1 – 11 were tested for their cytotoxic activities using six human cancer cell lines by the MTT method. However, none of the compounds exhibited detectable cytotoxicities (IC₅₀ >20 μm ).     

Phylogeny and biogeography of Aralia sect. Aralia (Araliaceae)

Aralia sect. Aralia (Araliaceae) consists of approximately eight species disjunctly distributed in Asia and North America. Phylogenetic and biogeographic analyses were conducted using sequences of the internal transcribed spacer regions of the nuclear ribosomal DNA. Aralia racemosa from eastern North America was sister to A. californica from western North America. Aralia cordata from eastern Asia did not form a species-pair relationship with the eastern North American A. racemosa. The two subspecies of A. racemosa formed a monophyletic group. Biogeographic analyses showed a close area relationship between eastern North America and western North America. The Himalayas were cladistically basal and eastern Asia was placed between the Himalayas and North America. The biogeographic analysis supported the origin of the eastern Asian and eastern North American disjunct pattern in Aralia sect. Aralia via the Bering land bridges. Comparisons with results of phylogenetic analyses of other genera suggested that (1) the floristic connection between eastern North America and western North America may be stronger than previously thought; and (2) the biogeographic patterns in the Northern Hemisphere are complex. Furthermore, a lack of correlation between sequence divergence values and phylogenetic positions was observed, suggesting the importance of a phylogenetic framework in biogeographic analyses.     

Triterpenoids from Meehania fargesii with Cytotoxic Activity1

In the investigation of Meehania fargesii, eighteen triterpenoids were isolated and identified, including a previously unknown compound with an 13,27-cycloursane skeleton, using techniques like 1D and 2D NMR, and HR-MS. Furthermore, the cytotoxicity of these compounds were evaluated against HCT116, MCF-7, and AGS cell lines using the CCK-8 method to examine their structure–activity relationship. Remarkably, compounds 13 and 16 exhibited higher cytotoxicity across all three cell lines compared to the positive drug. Western blot analysis revealed that these compounds activated apoptosis in HCT116 cells by promoting the Bax protein and inhibiting the Bcl-2 protein. This suggests that compounds 13 and 16 have potential as apoptosis-inducing agents in HCT116 cells.