共查询到20条相似文献,搜索用时 0 毫秒
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Richard Waldram 《BMJ (Clinical research ed.)》1970,4(5734):559-560
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J. R. O'Brien 《BMJ (Clinical research ed.)》1974,2(5909):52-53
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Wm. L. Hooper 《BMJ (Clinical research ed.)》1960,2(5215):1805-1806
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Ieva Zostautiene Rolf Jorde Henrik Schirmer Ellisiv B?geberg Mathiesen Inger Nj?lstad Maja-Lisa L?chen Tom Wilsgaard Ragnar Martin Joakimsen Elena Kamycheva 《PloS one》2015,10(12)
BackgroundThough the associations between low serum 25-hydroxyvitamin D (25(OH)D) levels and health outcomes such as type 2 diabetes (T2D), myocardial infarction (MI), cancer, and mortality are well-studied, the effect of supplementation with vitamin D is uncertain. This may be related to genetic differences. Thus, rs7968585, a single nucleotide polymorphism (SNP) of the vitamin D receptor (VDR), has recently been reported as a predictor of composite health outcome. We therefore aimed to evaluate whether rs7968585 predicts separate clinical outcomes such as T2D, MI, cancer, and mortality in a community-based Norwegian population.ConclusionsThe VDR-related SNP rs7968585 minor allele is a significant and positive predictor for T2D and possibly for MI. Since the functional mechanism of this SNP is not yet understood, and the association with T2D is reported for the first time, confirmatory studies are needed. 相似文献
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Eivind Myhre 《BMJ (Clinical research ed.)》1973,4(5894):737-738
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A. N. Nicolaides V. V. Kakkar J. T. G. Renney P. H. Kidner D. C. S. Hutchinson M. B. Clarke 《BMJ (Clinical research ed.)》1971,1(5746):432-434
In a study of 52 patients admitted into the coronary intensive care unit the incidence of deep-vein thrombosis was measured with the 125I-fibrinogen test. Of these patients 31 were eventually confirmed to be suffering from acute myocardial infarction. This preliminary study showed that in patients with a confirmed infarct who were not treated with anticoagulants the incidence of deep-vein thrombosis was 38% and in those treated it was 5·5%. In patients who were “severely ill” from whatever the cause there was a high incidence of deep-vein thrombosis (68%). 相似文献
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R. A. Murray Scott 《BMJ (Clinical research ed.)》1953,1(4821):1223-1224
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M. Toohey 《BMJ (Clinical research ed.)》1958,1(5065):252-255
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G. Riddell Royston 《BMJ (Clinical research ed.)》1970,1(5688):108-109