A Review of: “Gel Permeation Chromatography,Eds. K.H. Altgelt and L. Segal Marcel Dekker,Inc., New York 1971 xvii + 646 pages ill., hard cover $24.75”

A simple, rapid procedure for the purification of uricase from mammalian tissue is reported. The procedure is based on the precipitation of mammalian uricase under certain dialysis conditions, and on its low solubility near neutral pH. Exceptionally high yields of homogeneous enzyme are obtained.