DNA-damaged podocyte-CD8 T cell crosstalk exacerbates kidney injury by altering DNA methylation

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Bacteriophage antidefense genes that neutralize TIR and STING immune responses

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LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis

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Oxoeicosanoid signaling mediates early antimicrobial defense in zebrafish

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Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS

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MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells

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The human placenta exhibits a unique transcriptomic void

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METTL3-mediated m6A modification of IGFBP7-OT promotes osteoarthritis progression by regulating the DNMT1/DNMT3a-IGFBP7 axis

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A transcriptomic and proteomic atlas of obesity and type 2 diabetes in cynomolgus monkeys

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The CNC-family transcription factor Nrf3 coordinates the melanogenesis cascade through macropinocytosis and autophagy regulation

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Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance

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RNA-DNA hybrids prevent resection at dysfunctional telomeres

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Bub1 and Bub3 regulate metabolic adaptation via macrolipophagy in Drosophila

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Proteomic analysis of circulating immune cells identifies cellular phenotypes associated with COVID-19 severity

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Ketone bodies promote stroke recovery via GAT-1-dependent cortical network remodeling

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Multi-omics analysis reveals the chemoresistance mechanism of proliferating tissue-resident macrophages in PDAC via metabolic adaptation

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Extensive de novo activity stabilizes epigenetic inheritance of CG methylation in Arabidopsis transposons

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Metaphocytes are IL-22BP-producing cells regulated by ETS transcription factor Spic and essential for zebrafish barrier immunity

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POGZ suppresses 2C transcriptional program and retrotransposable elements

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MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy

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