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C. Giles Miller 《ZooKeys》2016,(550):71-81
Sherborn’s work on the Foraminifera clearly provided the initial spark to compile the major indexes for which he is famous. Contact and help from famous early micropalaeontologists such as T. Rupert Jones and Fortescue William Millett led Sherborn to produce his Bibliography of Foraminifera and subsequently a two-part Index of Foraminiferal Genera and Species. Edward Heron-Allen, whose mentor was Millett, was subsequently inspired by the bibliography to attempt to acquire every publication listed. This remarkable collection of literature was donated to the British Museum (Natural History) in 1926 along with the foraminiferal collections Heron-Allen had mainly purchased from early micropalaeontologists. This donation forms the backbone of the current NHM micropalaeontological collections. The NHM collections contain a relatively small amount of foraminiferal material published by Sherborn from the London Clay, Kimmeridge Clay and Speeton Clay. Another smaller collection reflects his longer-term interest in the British Chalk following regular fieldwork with A. W. Rowe. Other collections relating to Sherborn’s early published work, particularly with T. R. Jones, are not present in the collections but these collections may have been sold or deposited elsewhere by his co-workers.  相似文献   

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The first few words of the title of this symposium are “Anchoring Biodiversity Information”. In order to properly anchor anything for a long-lasting future, a solid foundation needs to have been laid. For the zoological portion of biodiversity information, that firm foundation is best exemplified in the works of Charles Davies Sherborn. This man, like others of his ilk, was intimately focused on indexing names. This incredible focus was a life-long passion for him and culminated in his 9500-page Index Animalium of over 400,000 names of animals. This Index represents not only one of the most prodigious efforts in publication by a single man and the single most important reference to names in zoology, but a permanent legacy to the efforts of an indexer that proved to be an inspiration to many.  相似文献   

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Gordon McOuat 《ZooKeys》2016,(550):57-69
By the late 19th Century, storms plaguing early Victorian systematics and nomenclature seemed to have abated. Vociferous disputes over radical renaming, the world-shaking clash of all-encompassing procrustean systems, struggles over centres of authority, and the issues of language and meaning had now been settled by the institution of a stable imperial museum and its catalogues, a set of rules for the naming of zoological objects, and a new professional class of zoologists. Yet, for all that tranquillity, the disputes simmered below the surface, re-emerging as bitter struggles over synonyms, trinomials, the subspecies category, the looming issues of the philosophy of scientific language, and the aggressive new American style of field biology – all pressed in upon the received practice of naming and classifying organisms and the threat of anarchy. In the midst rose an index. This paper will explore the context of CD Sherborn’s Index Animalium and those looming problems and issues which a laborious and comprehensive “index of nature” was meant to solve.  相似文献   

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Here we argue that the concept of strategies, as it was introduced into biology by John Maynard Smith, is a prime illustration of the four dimensions of theoretical biology in the post-genomic era. These four dimensions are: data analysis and management, mathematical and computational model building and simulation, concept formation and analysis, and theory integration. We argue that all four dimensions of theoretical biology are crucial to future interactions between theoretical and empirical biologists as well as with philosophers of biology.  相似文献   

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Annually, millions of tourists go on safari and visit zoos primarily to view large charismatic wildlife. These venues rely on the inherent appeal of these animals to increase visitation and anchor conservation efforts. In conservation campaigns, flagship species are used to stimulate a connection to a species and promote pro-conservation behaviors. However, empirical support for behavioral outcomes associated with flagships is lacking. Nor is it known how a connection to a species influences behaviors. This study explored (a) how tourists connect to wildlife, how this relationship is influenced by the on-site experience, and how these factors interact to influence behavior, and (b) how the experiences between safari and zoo venues differed. A model was developed using interactional theory and analyzed with structural equation modeling. Data were obtained from 416 tourists to Tanzanian parks and protected areas and 452 tourists to two U.S. zoos and one aquarium. An existing connection to wildlife and experiential factors directly influenced tourists’ connection to a species, but not behaviors. Tourists’ connection to a species had a significant positive influence on pro-conservation behaviors for individual species and general biodiversity. The influence of the experience was equivalent across safari and zoo venues. Results support the ability of safari and zoo wildlife tourism to produce conservation outcomes.  相似文献   

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An oil obtained from cow’s urine was examined by means of gas chromatography. Ethylbenzene, phenol, m-cresol, p-cresol, and p-ethylphenol were identified as the major components of the oil, while there were at least four components still remaining unknown.

A hypothesis concerning the degradation of equol,1) 7-hydroxy-3-(4’-hydroxy) chroman, to p-cresol and p-ethylphenol in the urine was proposed.  相似文献   

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Due to its public popularity, ornithology has a huge corpus of scientific publication for a relatively small number of species. Although there are global checklists of currently recognised taxa, there has been only limited, mainly individual, effort to build a nomenclatural database that the science of ornithology deserves. This is especially true in relation to concise synonymies. With the arrival of ZooBank and the Biodiversity Heritage Library, the time has come to develop synonymies and to add fuller bibliographic detail to databases. The preparation for both began at the start of the 20th century with extensive work by Sherborn and Richmond. I discuss their legacy, offer notes on significant work since then, and provide suggestions for what remains to be done. To make solid the foundations for ornithological nomenclature and taxonomy, especially for synonymies, ornithologists will need to collaborate much more and contribute to the digital infrastructure.  相似文献   

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Background

Alzheimer disease (AD) is a progressive neurodegenerative disease that destroys memory and cognitive skills. AD is characterized by the presence of two types of neuropathological hallmarks: extracellular plaques consisting of amyloid β-peptides and intracellular neurofibrillary tangles of hyperphosphorylated tau proteins. The disease affects 5 million people in the United States and 44 million world-wide. Currently there is no drug that can cure, stop or even slow the progression of the disease. If no cure is found, by 2050 the number of alzheimer’s patients in the U.S. will reach 15 million and the cost of caring for them will exceed $ 1 trillion annually.

Results

The present paper develops a mathematical model of AD that includes neurons, astrocytes, microglias and peripheral macrophages, as well as amyloid β aggregation and hyperphosphorylated tau proteins. The model is represented by a system of partial differential equations. The model is used to simulate the effect of drugs that either failed in clinical trials, or are currently in clinical trials.

Conclusions

Based on these simulations it is suggested that combined therapy with TNF- α inhibitor and anti amyloid β could yield significant efficacy in slowing the progression of AD.
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