共查询到20条相似文献,搜索用时 15 毫秒
1.
Harless WW 《Cancer cell international》2011,11(1):1
Background
Physiologic wound repair and tissue regeneration are associated with distinct cellular behaviors triggered by tissue damage. Normally quiescent stem cells proliferate to regenerate damaged tissue, while relatively immobile epithelial cells can transform into a motile, tissue invasive phenotype through a partial epithelial-mesenchymal transition. These distinct cellular behaviors may have particular relevance to how cancer cells can be predicted to behave after treatments damaging a tumor. 相似文献2.
Stefania Angelucci Marco Marchisio Fabrizio Di Giuseppe Laura Pierdomenico Marilisa Sulpizio Enrica Eleuterio Paola Lanuti Giuseppe Sabatino Sebastiano Miscia Carmine Di Ilio 《Proteome science》2010,8(1):18
Background
The human umbilical cord contains mucoid connective tissue and fibroblast-like cells. These cells named Wharton's jelly cells, (WJCs) display properties similar to mesenchymal stem cells therefore representing a rich source of primitive cells to be potentially used in regenerative medicine. 相似文献3.
Xu-Fang Yang Xu He Jian He Li-Hong Zhang Xue-Jin Su Zhi-Yong Dong Yun-Jian Xu Yan Li Yu-Lin Li 《Journal of biomedical science》2011,18(1):59
Background
Developing efficient methods to isolate and identify human adipose-derived mesenchymal stem cells (hADSCs) remains to be one of the major challenges in tissue engineering. 相似文献4.
Background
The gene expression pattern in tumor cells differs from that in corresponding normal cells. In order to identify differentially expressed genes in colorectal tumors and normal colorectal epithelium, a differential display experiment was used to compare RNA expression in normal and tumor tissue samples. 相似文献5.
Background
The goal of our study is to examine the effect of stimulating a two-dimensional sheet of myocardial cells. We assume that the stimulating electrode is located in a bath perfusing the tissue. 相似文献6.
Péricles Nóbrega Mendes Sheila Canevese Rahal Oduvaldo Câmara Marques Pereira-Junior Viciany Erique Fabris Sara Lais Rahal Lenharo João Ferreira de Lima-Neto Fernanda da Cruz Landim-Alvarenga 《Acta veterinaria Scandinavica》2009,51(1):12
Background
Barrier materials as cellulose membranes are used for guided tissue repair. However, it is essential that the surrounding tissues accept the device. The present study histologically evaluated tissue reaction to a microbial cellulose membrane after subcutaneous implantation in mice. Furthermore, the interaction between mesenchymal stem cells and the biomaterial was studied in vitro to evaluate its ability to act as cellular scaffold for tissue engineering. 相似文献7.
Sujeong Jang Hyong-Ho Cho Yong-Bum Cho Jong-Seong Park Han-Seong Jeong 《BMC cell biology》2010,11(1):25
Background
Adult mesenchymal stem cells (MSCs) derived from adipose tissue have the capacity to differentiate into mesenchymal as well as endodermal and ectodermal cell lineage in vitro. We characterized the multipotent ability of human adipose tissue-derived stem cells (hADSCs) as MSCs and investigated the neural differentiation potential of these cells. 相似文献8.
Ying Xue Zhe Xing Sølve Hellem Kristina Arvidson Kamal Mustafa 《Biomedical engineering online》2009,8(1):34-9
Background
Improved understanding of the interactions between bone cells and endothelial cells involved in osteogenesis should aid the development of new strategies for bone tissue engineering. The aim of the present study was to determine whether direct communication between bone marrow stromal cells (MSC) and human umbilical vein endothelial cells (EC) could influence the osteogenic potential of MSC in osteogenic factor-free medium. 相似文献9.
Yunkui Zhu C Magnus Sköld Xiangde Liu Hangjun Wang Tadashi Kohyama Fu-Qiang Wen Ronald F Ertl Stephen I Rennard 《Respiratory research》2001,2(5):295-7
Background
Inflammatory cells are believed to play a prominent role during tissue repair and remodeling. Since repair processes develop and mature over extended time frames, the present study was designed to evaluate the effect of monocytes and fibroblasts in prolonged culture in three-dimensional collagen gels. 相似文献10.
Helen E Gruber Gretchen L Hoelscher Jane A Ingram Natalia Zinchenko Edward N HanleyJr 《BMC biotechnology》2010,10(1):5
Background
Senescent cells are well-recognized in the aging/degenerating human disc. Senescent cells are viable, cannot divide, remain metabolically active and accumulate within the disc over time. Molecular analysis of senescent cells in tissue offers a special challenge since there are no cell surface markers for senescence which would let one use fluorescence-activated cell sorting as a method for separating out senescent cells. 相似文献11.
Church LD Filer AD Hidalgo E Howlett KA Thomas AM Rapecki S Scheel-Toellner D Buckley CD Raza K 《Arthritis research & therapy》2010,12(5):R184
Introduction
Th17 cells have been implicated in the pathogenesis of rheumatoid arthritis (RA). The aim of this study was to systematically analyse the phenotype, cytokine profile and frequency of interleukin-17 (IL-17) producing CD4-positive T cells in mononuclear cells isolated from peripheral blood, synovial fluid and synovial tissue of RA patients with established disease, and to correlate cell frequencies with disease activity. 相似文献12.
Recurrence of primary extramedullary plasmacytoma in breast both simulating primary breast carcinoma
Background
Extramedullary myelomas (plasmacytoma) are malignant proliferations of plasma cells in the absence of bone involvement. When they occur in the soft tissue they usually involve the upper respiratory tract and oral cavity. Extramedullary plasmacytomas of breast are uncommon. 相似文献13.
Introduction
Infrapatellar fat pad (IPFP) is a possible source of stem cells for the repair of articular cartilage defects. In this study, adherent proliferative cells were isolated from digests of IPFP tissue. The effects of the expansion of these cells in fibroblast growth factor-2 (FGF-2) were tested on their proliferation, characterisation, and chondrogenic potential. 相似文献14.
Johanna B Drott Oleg Alexeyev Patrik Bergström Fredrik Elgh Jan Olsson 《BMC microbiology》2010,10(1):126
Background
The immune stimulating bacterium Propionibacterium acnes is a frequent colonizer of benign and malignant prostate tissue. To understand the pathogenesis of the earliest phase of this infection, we examined the P. acnes triggered immune response in cultivated prostate epithelial cells. 相似文献15.
Background
Biological studies and medical application of stem cells often require the isolation of stem cells from a mixed cell population, including the detection of cancer stem cells in tumor tissue, and isolation of induced pluripotent stem cells after eliciting the expression of specific genes in adult cells. Here we report the detection of Oct-4 mRNA and SSEA-1 protein in live carcinoma stem cells using respectively molecular beacon and dye-labeled antibody, aiming to establish a new method for stem cells detection and isolation. 相似文献16.
Laure-Emmanuelle Zaragosi Brigitte Wdziekonski Coralie Fontaine Phi Villageois Pascal Peraldi Christian Dani 《BMC cell biology》2008,9(1):11
Background
Multipotent stem cells exist within adipose tissue throughout life. An abnormal recruitment of these adipose precursor cells could participate to hyperplasia of adipose tissue observed in severe obesity or to hypoplasia of adipose tissue observed in lipodystrophy. Therefore, pharmacological molecules that control the pool of stem cells in adipose tissue are of great interest. Glycogen Synthase Kinase (GSK) 3 has been previously described as involved in differentiation of preadipose cells and might be a potential therapeutic target to modulate proliferation and differentiation of adipocyte precursors. However, the impact of GSK3 inhibition on human adipose-derived stem cells remained to be investigated. The aim of this study was to investigate GSK3 as a possible target for pharmacological inhibition of stem cell adipogenesis. To reach this goal, we studied the effects of pharmacological inhibitors of GSK3, i.e. lithium chloride (LiCl) and BIO on proliferation and adipocyte differentiation of multipotent stem cells derived from human adipose tissue. 相似文献17.
Dimitrios Makrygiannakis Shankar Revu Petra Neregård Erik af Klint Omri Snir Cecilia Grundtman Anca Irinel Catrina 《Arthritis research & therapy》2008,10(6):R147
Introduction
Rheumatoid arthritis (RA) is characterized by synovial inflammation with local accumulation of mononuclear cells such as macrophages and lymphocytes. We previously demonstrated that intra-articular glucocorticoids decrease the synovial tissue (ST) T-cell population and therefore aimed to investigate whether this is mediated through modulation of apoptosis. 相似文献18.
Zvia Agur Yuri Kogan Liora Levi Hannah Harrison Rebecca Lamb Oleg U Kirnasovsky Robert B Clarke 《Biology direct》2010,5(1):20
Background
The balance between self-renewal and differentiation of stem cells is expected to be tightly controlled in order to maintain tissue homeostasis throughout life, also in the face of environmental hazards. Theory, predicting that homeostasis is maintained by a negative feedback on stem cell proliferation, implies a Quorum Sensing mechanism in higher vertebrates. 相似文献19.
Effect of adiponectin on bovine granulosa cell steroidogenesis,oocyte maturation and embryo development 总被引:1,自引:0,他引:1
Virginie Maillard Svetlana Uzbekova Florence Guignot Christine Perreau Christelle Ramé Stéphanie Coyral-Castel Joëlle Dupont 《Reproductive biology and endocrinology : RB&E》2010,8(1):23
Background
Adiponectin is an adipokine, mainly produced by adipose tissue. It regulates several reproductive processes. The protein expression of the adiponectin system (adiponectin, its receptors, AdipoR1 and AdipoR2 and the APPL1 adaptor) in bovine ovary and its role on ovarian cells and embryo, remain however to be determined. 相似文献20.
Elizabeth A Mitchell Benjamin T Chaffey Andrew W McCaskie Jeremy H Lakey Mark A Birch 《BMC biology》2010,8(1):57