Emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States

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Differential m6A RNA landscapes across hematopoiesis reveal a role for IGF2BP2 in preserving hematopoietic stem cell function

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Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity

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SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States

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Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells

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Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression

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PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing

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Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission

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Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling

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Methylation of histone H3 at lysine 37 by Set1 and Set2 prevents spurious DNA replication

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Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells

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Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks

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Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1

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Fumarate inhibits PTEN to promote tumorigenesis and therapeutic resistance of type2 papillary renal cell carcinoma

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NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis

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Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation

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Crosstalk between ILC2s and Th2 cells varies among mouse models

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An Extended Conformation for K48 Ubiquitin Chains Revealed by the hRpn2:Rpn13:K48-Diubiquitin Structure

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Loss of Ezh2 function remodels the DNA replication initiation landscape

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A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells

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