Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy

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Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells

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Discovering dominant tumor immune archetypes in a pan-cancer census

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Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells

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Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment

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linc-AAM Facilitates Gene Expression Contributing to Macrophage Activation and Adaptive Immune Responses

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DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs

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Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment

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Spatial and single-cell transcriptomics decipher the cellular environment containing HLA-G+ cancer cells and SPP1+ macrophages in colorectal cancer

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Polyploid mitosis and depolyploidization promote chromosomal instability and tumor progression in a Notch-induced tumor model

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TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state

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Inter- and intra-tumor heterogeneity of genetic and immune profiles in inherited renal cell carcinoma

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NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion

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CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b−CD103+ DCs

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Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis

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Bifidobacteria-mediated immune system imprinting early in life

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Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin

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T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants

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Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin

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Microbial exposure during early human development primes fetal immune cells

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