A Cervical Cytology Program in General Practice

In a six-year period 723 women were examined using cervical cytology smears. Fifteen cancers of the cervix were discovered, including two invasive growths and 13 carcinoma in situ. A careful follow-up was carried out, and the later appearance of cancer was noted in 12 of 41 patients who initially showed only atypical cells. It is recommended that all patients showing “positive” cells (atypical, suspicious, or cancer morphology cells) undergo cone biopsy for definitive histological diagnosis. Target lesions should have punch biopsy. Four cancers were found in 170 obstetrical patients, and it is recommended that this proved high-risk group be screened both prenatally and postnatally. The importance of annual screening of all women over 20 years of age for cancer of the cervix by cytological methods is emphasized.     

General Practice Observed: Survey of General Practice Records

A study of a sample of records from eight general practices showed that 10% of patients'' ages were not recorded, that 99% of males had no indication of their marital state, and 60% did not have an occupation recorded. In recording of disease episodes a diagnosis was recorded in a little over half of the episodes and was the only recorded item in 10% of records. The recording of the therapeutic agent used was the most frequently recorded item, occurring in 70% of episodes, but the amount prescribed was recorded in only one-quarter of the episodes and the dosage in less than one-fifth. Less than half of the episodes had any symptoms recorded and only one-third had a physical sign recorded.     

Rapid Cervical Cytology Screening

2030 Papanicolaou-stained cervical smears were submitted for rapid screening prior to routine screening; 30 seconds were allowed for each slide, and those thought to be abnormal were identified. The results were compared with those of conventional screening. All severe and moderately dyskaryotic cases were detected by the rapid technique, as were the majority of mild dyskaryosis and borderline cases. When a laboratory has a backlog it may be worth rapid-screening all slides in addition to routine screening, so that patients most at risk can receive prompt treatment.     

薄层液基细胞学检查在宫颈普查中应用的临床分析

目的:评价薄层液基细胞学检查在宫颈普查中应用的临床价值。方法:选择经薄层液基细胞学门诊普查妇女520例,其中经TCT检查结果提示ASCUS以上的妇女76例,均进一步采取阴道镜下宫颈活检病理检查,将TCT检查结果与阴道镜下宫颈活检病理检查结果对比分析。结果:TCT检查结果具有较高的检出率及符合率,HSIL组、SCC组与LSIL组符合率比较,差异具有统计学意义(P<0.05)。结论:TCT检查作为妇科宫颈普查的方法,具有检出率及符合率高的优点;检查结果为HSIL或SCC时,应引起临床极高度重视。     

薄层液基细胞学检查在宫颈普查中应用的临床分析

目的：评价薄层液基细胞学检查在宫颈普查中应用的临床价值。方法：选择经薄层液基细胞学门诊普查妇女520例,其中经TCT检查结果提示ASCUS以上的妇女76例,均进一步采取阴道镜下宫颈活检病理检查,将TCT检查结果与阴道镜下宫颈活检病理检查结果对比分析。结果：TCT检查结果具有较高的检出率及符合率,HSIL组、SCC组与LSIL组符合率比较,差异具有统计学意义（P〈0.05）。结论：TCT检查作为妇科宫颈普查的方法,具有检出率及符合率高的优点;检查结果为HSIL或SCC时,应引起临床极高度重视。     

Examination for the Certificate in Advanced Practice in Cervical Cytology – the first year''s experience

Following the decision to establish an Advanced Biomedical Scientist Practitioner grade for senior biomedical scientists in the NHS Cervical Screening Programme, a conjoint examination board has been appointed by the Royal College of Pathologists and Institute of Biomedical Science to oversee the Certificate in Advanced Practice in Cervical Cytology examination. The examination consists of a multiple-choice paper, short-answer written questions and practical microscopy sections covering screening of unmarked slides, and more complex discussion cases. In the first year there were 58 entries with 29 successful candidates, a pass rate of 50%. The standard of performance in the examination showed a wide range, and some candidates appear to have underestimated the degree of preparation, knowledge or level of microscopy skill required.     

宫颈液基超薄细胞学检查临床应用价值探讨

目的探讨宫颈液基超薄细胞学检查（Thinp rep cytologic,TCT）和Bethesda系统（TBS）在宫颈病变诊断中的临床价值。方法对3146例本院宫颈疾病就诊者行TCT检查和TBS细胞学分类诊断,对TCT检查异常者进行阴道镜病理检查。结果异常涂片208例（占6．61％）,其中不典型鳞状细胞（ASC）68例（2．19％）,低度鳞状上皮内瘤变（LSIL）95例（3．02％）高度鳞状上皮内瘤变（HSIL）41例（1．31％）。鳞状细胞癌（SCC）4例（0．12％）。异常细胞涂片30-39岁80例（38．1％）,40—49岁55例（26．12％）,与其他年龄组比较差异有统计学意义（P〈0．05）。TCT检查与病理检查符合率分别为LSIL81％,HSIL92％,SCC100％,两者比较差异无统计学意义。结论TCT结合TBS应用于宫颈细胞涂片配合阴道镜活检,是筛查和诊断宫颈癌前病变的可靠手段。