共查询到20条相似文献,搜索用时 15 毫秒
1.
Background
Hox genes are critical for patterning the bilaterian anterior-posterior axis. The evolution of their clustered genomic arrangement and ancestral function has been debated since their discovery. As acoels appear to represent the sister group to the remaining Bilateria (Nephrozoa), investigatingHox gene expression will provide an insight into the ancestral features of theHox genes in metazoan evolution. 相似文献2.
Background
DUX4 is causally involved in the molecular pathogenesis of the neuromuscular disorder facioscapulohumeral muscular dystrophy (FSHD). It has previously been proposed to have arisen by retrotransposition of DUXC, one of four known intron-containing DUX genes. Here, we investigate the evolutionary history of this multi-member double-homeobox gene family in eutherian mammals. 相似文献3.
Effect of iron on the expression of sirR and sitABC in biofilm-associated Staphylococcus epidermidis
Caroline Massonet Valerie Pintens Rita Merckx Jozef Anné Elke Lammertyn Johan Van Eldere 《BMC microbiology》2006,6(1):103
Background
Different gene expression patterns correlate with the altered phenotype in biofilm-associated bacteria. Iron and iron-linked genes are thought to play a key-role in biofilm formation. The expression of Fe-linked genes (sirR, sitABC operon) in Staphylococcus epidermidis, was compared in planktonic versus sessile bacteria in vitro and in vivo in a subcutaneous foreign body rat model. 相似文献4.
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Xiangmin Zhang Soo-Young Wanda Karen Brenneman Wei Kong Xin Zhang Kenneth Roland Roy Curtiss 《BMC microbiology》2011,11(1):31
Background
Salmonella has been employed to deliver therapeutic molecules against cancer and infectious diseases. As the carrier for target gene(s), the cargo plasmid should be stable in the bacterial vector. Plasmid recombination has been reduced in E. coli by mutating several genes including the recA, recE, recF and recJ. However, to our knowledge, there have been no published studies of the effect of these or any other genes that play a role in plasmid recombination in Salmonella enterica. 相似文献6.
Mayken W Wadman Ronald P de Vries Stefanie IC Kalkhove Gerrit A Veldink Johannes FG Vliegenthart 《BMC microbiology》2009,9(1):59
Background
Aspergillus niger is an ascomycetous fungus that is known to reproduce through asexual spores, only. Interestingly, recent genome analysis of A. niger has revealed the presence of a full complement of functional genes related to sexual reproduction [1]. An example of such genes are the dioxygenase genes which in Aspergillus nidulans, have been shown to be connected to oxylipin production and regulation of both sexual and asexual sporulation [2–4]. Nevertheless, the presence of sex related genes alone does not confirm sexual sporulation in A. niger. 相似文献7.
Sandra Thibivilliers Trupti Joshi Kimberly B Campbell Brian Scheffler Dong Xu Bret Cooper Henry T Nguyen Gary Stacey 《BMC plant biology》2009,9(1):46
Background
Phaseolus vulgaris (common bean) is the second most important legume crop in the world after soybean. Consequently, yield losses due to fungal infection, like Uromyces appendiculatus (bean rust), have strong consequences. Several resistant genes were identified that confer resistance to bean rust infection. However, the downstream genes and mechanisms involved in bean resistance to infection are poorly characterized. 相似文献8.
Soroush Sharbati Kira Schramm Sonja Rempel Hwa Wang Ronny Andrich Verena Tykiel Ralph Kunisch Astrid Lewin 《BMC microbiology》2009,9(1):31
Background
Highly pathogenic mycobacteria like Mycobacterium tuberculosis are characterised by their slow growth and their ability to reside and multiply in the very hostile phagosomal environment and a correlation between the growth rate of mycobacteria and their pathogenicity has been hypothesised. Here, porin genes from M. fortuitum were cloned and characterised to address their impact on the growth rate of fast-growing and pathogenic mycobacteria. 相似文献9.
Matthias B Van Hiel Pieter Van Wielendaele Liesbet Temmerman Sofie Van Soest Kristel Vuerinckx Roger Huybrechts Vanden Jozef Broeck Gert Simonet 《BMC molecular biology》2009,10(1):56
Background
To obtain reliable quantitative RT-PCR data, normalization relative to stable housekeeping genes is required. However, in practice, expression levels of 'typical' housekeeping genes have been found to vary between tissues and under different experimental conditions. To date, validation studies of reference genes in insects are extremely rare and have never been performed in locusts. In this study, putative housekeeping genes were identified in the desert locust, Schistocerca gregaria and two different software programs (geNorm and Normfinder) were applied to assess the stability of thesegenes. 相似文献10.
Background
H ox genes are known to play a key role in shaping the body plan of metazoans. Evolutionary dynamics of these genes is therefore essential in explaining patterns of evolutionary diversity. Among extant sarcopterygians comprising both lobe-finned fishes and tetrapods, our knowledge of the Hox genes and clusters has largely been restricted in several model organisms such as frogs, birds and mammals. Some evolutionary gaps still exist, especially for those groups with derived body morphology or occupying key positions on the tree of life, hindering our understanding of how Hox gene inventory varied along the sarcopterygian lineage. 相似文献11.
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Background
Although Aspergillus fumigatus is an important human fungal pathogen there are few expression systems available to study the contribution of specific genes to the growth and virulence of this opportunistic mould. Regulatable promoter systems based upon prokaryotic regulatory elements in the E. coli tetracycline-resistance operon have been successfully used to manipulate gene expression in several organisms, including mice, flies, plants, and yeast. However, the system has not yet been adapted for Aspergillus spp. 相似文献13.
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Alejandro Hernández-Morales Susana De la Torre-Zavala Enrique Ibarra-Laclette José Luis Hernández-Flores Alba Estela Jofre-Garfias Agustino Martínez-Antonio Ariel álvarez-Morales 《BMC microbiology》2009,9(1):257
Background
Pseudomonas syringae pv. phaseolicola is a Gram-negative plant-pathogenic bacterium that causes "halo blight" disease of beans (Phaseolus vulgaris L.). This disease affects both foliage and pods, and is a major problem in temperate areas of the world. Although several bacterial genes have been determined as participants in pathogenesis, the overall process still remains poorly understood, mainly because the identity and function of many of the genes are largely unknown. In this work, a genomic library of P. syringae pv. phaseolicola NPS3121 was constructed and PCR amplification of individual fragments was carried out in order to print a DNA microarray. This microarray was used to identify genes that are differentially expressed when bean leaf extracts, pod extracts or apoplastic fluid were added to the growth medium. 相似文献15.
Qian-Tao Jiang Yu-Ming Wei Feng Wang Ji-Rui Wang Ze-Hong Yan You-Liang Zheng 《BMC plant biology》2009,9(1):16
Background
High-molecular-weight glutenin subunits (HMW-GSs) have been considered as most important seed storage proteins for wheat flour quality. 1Ay subunits are of great interest because they are always silent in common wheat. The presence of expressed 1Ay subunits in diploid and tetraploid wheat genotypes makes it possible to investigate molecular information of active 1Ay genes. 相似文献16.
17.
Background
Genomic imprinting is an epigenetic chromosomal modification in the gametes or zygotes that results in a non-random monoallelic expression of specific autosomal genes depending upon their parent of origin. Approximately 44 human genes have been reported to be imprinted. A majority of them are clustered, including some on chromosome segment 11p15.5. We report here the imprinting status of the SLC22A1LS gene from the human chromosome segment 11p15.5 相似文献18.
Alejandro Zú?iga Christian H?dar Patricia Hanna Freddy Ibá?ez Pablo Moreno Rodrigo Pulgar Luis Pastenes Mauricio González Verónica Cambiazo 《BMC biology》2009,7(1):61
Background
Morphogenetic events that shape the Drosophila melanogaster embryo are tightly controlled by a genetic program in which specific sets of genes are up-regulated. We used a suppressive subtractive hybridization procedure to identify a group of developmentally regulated genes during early stages of D. melanogaster embryogenesis. We studied the spatiotemporal activity of these genes in five different intervals covering 12 stages of embryogenesis. 相似文献19.
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