共查询到20条相似文献,搜索用时 15 毫秒
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Daniel H. Scharf Axel A. Brakhage Prasun K. Mukherjee 《Environmental microbiology》2016,18(4):1096-1109
Gliotoxin (GT) is the most important epidithiodioxopiperazine (ETP)‐type fungal toxin. GT was originally isolated from Trichoderma species as an antibiotic substance involved in biological control of plant pathogenic fungi. A few isolates of GT‐producing Trichoderma virens are commercially marketed for biological control and widely used in agriculture. Furthermore, GT is long known as an immunosuppressive agent and also reported to have anti‐tumour properties. However, recent publications suggest that GT is a virulence determinant of the human pathogen Aspergillus fumigatus. This compound is thus important on several counts – it has medicinal properties, is a pathogenicity determinant, is a potential diagnostic marker and is important in biological crop protection. The present article addresses this paradox and the ecological role of GT. We discuss the function of GT as defence molecule, the role in aspergillosis and suggest solutions for safe application of Trichoderma‐based biofungicides. 相似文献
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Traditionally mire ecosystems (especially bogs) have been viewed as stable systems with slow changes in the vegetation over time. In this study the mire Åkhultmyren, south‐central Sweden was re‐investigated in 1997 after 40 yr of continued natural development. The results show a high degree of dynamics in a Sphagnum dominated bog and fen. Altogether 97 vascular plant and bryophyte species were recorded in the two inventories of the bog and poor fen vegetation. pH and electrical conductivity in the mire water were also surveyed. In 1997 we found 10 new species and that 8 species had disappeared since 1954 but the over‐all mean number of species per plot (size 400 m2) had hardly changed. However, 21% of the species increased and 21% decreased significantly in frequency. Most of the species that decreased in frequency were low‐grown vascular plants, most common in wet microhabitats. Vascular plant species that increased in frequency included trees (defined as >1.3 m in height) and were generally taller than the unchanged or decreasing species. The frequency of dwarf shrubs and hummock bryophytes increased too. Areas with an initial pH of 4.5–5.0 showed the strongest decrease in pH, coinciding with an enlarged distribution of some Sphagnum species. The species diversity increased on the bog, but decreased in the wettest parts of the fen, where the pH also decreased. Species with unchanged or increasing frequency often showed high capacity to colonise new plots. On average the sum of gains and losses of species in the plots in 1997 was ca 50% of the species number in 1954. The vegetation changes indicate a drier mire surface and an increased availability of nitrogen. The increased tree cover may have triggered further changes in the plant cover. 相似文献
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Mark S. Mosko 《The journal of the Royal Anthropological Institute》2013,19(3):482-509
Omarakana is arguably the most renowned village in the Trobriand and anthropological worlds. It is the very centre and wellspring of the North Kiriwinan universe and thus a sacred site, serving as the home of the Tabalu chiefly paramountcy. For us anthropologists, it is ground zero for our field methodology, thanks to Malinowski's pioneering research, and probably Melanesia's most hierarchical polity. Ironically, though, very little is actually known ethnographically about Omarakana's spatial layout. In this article I seek to compensate for that deficiency, arguing that Omarakana's seemingly concentric contours encode transformations of indigenous symbolism involving recurrent metaphors drawn from at least three conjoined semantic contexts of wide distribution across the Austronesian sphere and beyond: the double bisection of ‘male’ versus ‘female’; the botanical imagery of ‘base’, ‘body’, ‘tip’, and ‘fruit’; and various elements of ‘canoe’ symbolism. This alternative view of Omarakana's spatio‐temporal plan sheds new light on various additional dimensions of Trobriand sociality and cosmology while elaborating classic and contemporary anthropological theories of dualism. 相似文献
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Langlois PH Marengo LK Canfield MA 《Birth defects research. Part A, Clinical and molecular teratology》2011,91(10):902-917
BACKGROUND: Few studies have reported time trends for total birth defects or for a comprehensive range of phenotypes. METHODS: We examined data from the Texas Birth Defects Registry (TBDR) from 1999 through 2007. Poisson regression was used to fit trend lines to birth prevalence over time for total birth defects (each infant/fetus counted once), for every birth defect collected by the TBDR, and for subsets of cases or defects grouped various ways. RESULTS: From 1999 through 2007, birth prevalence of total birth defects in Texas increased 3.6% per year. Increases were observed in all population groups, persisted after adjustment for demographic characteristics, and were strongest in regions of Texas that were more urban. There was a wide variety of different defects showing significant increases. The trends of several defects were driven by their mild cases. Perhaps the most compelling finding was that larger upward trends were observed in defects that had been rated as more susceptible to diagnostic variation. One notable exception to that was gastroschisis, which showed an average increase of over 5% per year, the total birth defects rate in TBDR increased at 3.6% per year, similar to 3.7% per year in birth certificate check boxes. CONCLUSIONS: In our opinion, the weight of evidence in our study suggests that the observed increase over time in total birth defects and in many specific birth defects is artifactual. This likely reflects increased awareness, referral, detection, or documentation in health care facilities visited by TBDR staff, resulting in more complete ascertainment by the registry, rather than a true change over time in the occurrence of most birth defects. Birth Defects Research (Part A), 2011. © 2011 Wiley‐Liss, Inc. 相似文献
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The perennial grass triploid Miscanthus × giganteus is a promising renewable bioenergy feedstock in the United States and Europe. Originating from eastern Asia, this species is a sterile hybrid cross between M. sinensis and M. sacchariflorus. While research has begun to examine the impacts of M. sinensis and triploid M. × giganteus on the landscape, M. sacchariflorus has been largely overlooked in the peer‐reviewed literature. This review article discusses the origin, uses, distribution, and invasive potential of M. sacchariflorus. M. sacchariflorus is capable of producing high yields (10.7 t DM ha?1 yr?1), generally does not reproduce by seed, and can be challenging to establish due to poor cold tolerance, likely due to the limited germplasm used in evaluations. However, M. sacchariflorus has abundant and aggressively spreading rhizomes, which underscores its invasive risk. In the United States, it is listed as escaped from cultivation in at least eight states, primarily in the Midwest, although it is likely that not all populations have been reported. As such, it is essential to generate a comprehensive dataset of all known M. sacchariflorus populations and monitor any continued spread of this species. 相似文献
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Vidana R Sullivan A Billström H Ahlquist M Lund B 《Letters in applied microbiology》2011,52(2):109-115
Aims: Enterococcus faecalis is associated with a significant number of refractory endodontic infections. Previous studies report a prevalence of Ent. faecalis ranging from 24% up to 77% in teeth with failed endodontic treatment. The origin of the micro‐organism remains unclear, as enterococci do not belong to the normal oral microflora. The aim of this study was to determine whether these enterococci were of endogenous or exogenous origin. Methods and Results: Fifty consecutive patients with apical periodontitis in need of endodontic orthograde re‐treatment were included. Samples were collected from root canals, saliva and faeces and subjected to microbiological culturing. The genetic relationship between Ent. faecalis from root canals and isolates from the different host sources was determined using pulsed‐field gel electrophoresis. In 16% (8/50) of the patients, enterococci were collected from the root canal samples. The genetic analysis showed that the isolates from the root canals were not related to those from the normal gastrointestinal microflora. None of these patients had enterococci in their saliva samples. Conclusions: Endodontic infections with Ent. faecalis are probably not derived from the patient’s own normal microflora, which indicates that these infections ent. faecalis are of exogenous origin. Significance and Impact of the Study: This is the first study to genetically compare endodontic infectious Ent. faecalis isolates with isolates from the hosts’ own normal microflora. 相似文献
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Learning and Memory in Juvenile Zebrafish: What makes the Difference – Population or Rearing Environment?
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The ability to learn and remember about the surrounding environment is crucial for the survival of organisms in their natural habitats. Adults of numerous fish species have been shown to display sophisticated behaviour related to learning and memory. This study deals with testing learning abilities among juveniles (10 wks old) of zebrafish (Danio rerio) through a simple task of finding food. We compared the performance of juveniles from two populations, a wild collected from a natural habitat and an aquarium‐bred purchased from a pet shop, reared in bare environment (lacking visual cues). Additionally, we also tested the effect of early habitat enrichment on the performance among juveniles of the aquarium‐bred population. The experiments involved training fishes to solve a simple maze (with a food reward at the end) and testing their memory. Learning was measured based on the time taken to complete the task (performance time) of finding food in the maze‐arena across repeated trials. Our results showed that juveniles from the two populations possessed significantly different learning abilities. There were population differences in exploratory tendency and time taken to accomplish the task. However, when memory was tested based on performance time between training and test day, individuals (from both populations) were found to be poor at memorizing learnt tasks. On the other hand, juveniles (belonging to aquarium‐bred population) reared in spatially complex environments displayed higher rates of learning and were capable of remembering learnt tasks better than their counterparts from bare environments. This study thus demonstrates the importance of rearing conditions and natural ecology in ontogenetic development of learning and memory functions among zebrafish. 相似文献
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John M. Sedivy Jill A. Kreiling Nicola Neretti Marco De Cecco Steven W. Criscione Jeffrey W. Hofmann Xiaoai Zhao Takahiro Ito Abigail L. Peterson 《BioEssays : news and reviews in molecular, cellular and developmental biology》2013,35(12):1035-1043
Here we present and develop the hypothesis that the derepression of endogenous retrotransposable elements (RTEs) – “genomic parasites” – is an important and hitherto under‐unexplored molecular aging process that can potentially occur in most tissues. We further envision that the activation and continued presence of retrotransposition contribute to age‐associated tissue degeneration and pathology. Chromatin is a complex and dynamic structure that needs to be maintained in a functional state throughout our lifetime. Studies of diverse species have revealed that chromatin undergoes extensive rearrangements during aging. Cellular senescence, an important component of mammalian aging, has recently been associated with decreased heterochromatinization of normally silenced regions of the genome. These changes lead to the expression of RTEs, culminating in their transposition. RTEs are common in all kingdoms of life, and comprise close to 50% of mammalian genomes. They are tightly controlled, as their activity is highly destabilizing and mutagenic to their resident genomes. 相似文献
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Alexandra A.E. van der Geer Mark V. Lomolino George Lyras 《Journal of Biogeography》2018,45(3):515-529
Aim
To assess whether mammalian species introduced onto islands across the globe have evolved to exhibit body size patterns consistent with the ‘island rule,’, and to test an ecological explanation for body size evolution of insular mammals.Location
Islands worldwide.Methods
We assembled data on body mass, geographical characteristics (latitude, maximum elevation) and ecological communities (number of mammalian competitors, predators and prey) for 385 introduced populations across 285 islands, comprising 56 species of extant, non‐volant mammals. We used linear regression, ANCOVA and regression tree analyses to test whether introduced populations of mammals exhibit the island rule pattern, whether the degree of body size change increased with time in isolation and whether residual variation about the general trend can be attributed to the geographical and ecological characteristics of the islands.Results
Introduced populations follow the predicted island rule trend, with body size shifts more pronounced for populations with greater residence times on the islands. Small mammals evolved to larger body sizes in lower latitudes and on islands with limited topographic relief. Consistent with our hypothesis on the ecology of evolution, body size of insular introduced populations was influenced by co‐occurring species of mammalian competitors, predators and prey.Conclusion
The island rule is a pervasive pattern, exhibited across a broad span of geographical regions, taxa, time periods and, as evidenced here, for introduced as well as native mammals. Time in isolation impacts body size evolution profoundly. Body size shift of introduced mammals was much more pronounced with increasing residence times, yet far less than that exhibited by native, palaeo‐insular mammals (residence times > 10,000 years). Given the antiquity of many species introductions, it appears that much of what we view as the natural character and ecological dynamics of recent insular communities may have been rendered artefacts of ancient colonizations by humans and commensals. 相似文献15.
Shai Meiri 《Global Ecology and Biogeography》2011,20(1):203-207
Despite the great interest it generates, the definition of Bergmann's Rule is vague and often contested. Debate focuses on whether the rule should be described in terms of pattern or process, what taxa it should apply to and what taxonomic level it should be associated with. Here I review the historical development of studies of Bergmann's Rule. I suggest that Bergmann thought that his rule should be strongest at the intra‐specific level, rather than between closely related species as is usually thought. I argue that the rule is a pattern that can be studied regardless of mechanism in any taxon and at any taxonomic level. 相似文献
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Kok R 《Tijdschrift voor gerontologie en geriatrie》2004,35(2):65-71
Depression in the elderly is often thought to have a different clinical presentation in many patients. This so-called atypical depression is characterised by less sadness and feelings of guilt and more somatic symptoms, impaired cognition and behavioural symptoms. Studies that compare depressive signs and symptoms in elderly and younger patients are reviewed. Published studies do not support the suggestion that major depression in the elderly often have a different clinical presentation. Vascular depression and depression in patients with severe dementia may be exceptions. Conceptual and methodological issues that play an important role are discussed. 相似文献
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The long held view that annelids and arthropods are closely related (Articulata) has been challenged recently by phylogenetic analyses using molecular data. The outcome of these studies is a clade of moulting animals (Ecdysozoa) comprising arthropods and some taxa of the nemathelminth worms. Monophyly of the Ecdysozoa has not yet been shown convincingly on morphological evidence, but is strongly supported by molecular data. The implication of the Ecdysozoa hypothesis is that the type of segmentation found in annelids and arthropods must be either convergent or an ancestral feature of protostomes or even bilaterians. The present review discusses aspects of segmentation in annelids and arthropods at the genetic, cellular, morphogenetic and morphological levels. Based on numerous similarities not shared with other bilaterian taxa it is suggested that segmentation of annelids and arthropods is homologous and apomorphic for a monophyletic Articulata. However, the challenge provided by the molecular analyses should stimulate research programmes gaining more data such as on additional genes, cleavage patterns, molecular developmental biology, and the comparison of nervous systems at the level of single neurons. 相似文献
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Hai Ren Hongfang Lu Weijun Shen Charlie Huang Qinfeng Guo Zhi’an Li Shuguang Jian 《Ecological Engineering》2009,35(8):1243-1248
By the end of 1990s when China initiated a 10-year mangrove reforestation project, the mangrove forest area had decreased from 250,000 to 15,000 ha. Over 80% of current Chinese mangroves are degraded secondary forests or plantations. As an initial restoration and reforestation effort, Sonneratia apetala, a native of India, Bengal and Sri Lanka, was introduced in 1985 to Dong Zhaigang Mangrove Nature Reserve in Hainan Island from Bengal. It has then been introduced into other places since 1991. However, the further use of the species is becoming increasingly controversial as there are emerging signs that it may become invasive in certain locations. A comprehensive evaluation of the species’ condition in China regarding benefits and risks is critically needed. Here, we map the introduction and dispersal routes and monitor the growth of S. apetala in China from 1985 to 2006. S. apetala grows fast and performs well in the introduced 2300 ha muddy beaches area. It greatly improves the soil fertility and shows a suite of suitable characteristics as a pioneer restoration species. Currently, no natural invasion of S. apetala has been observed in the northern mangrove area. However, invasion into natural forests does occur in southerly locations such as Shenzhen, Zhanjiang and Dong Zhaigang. In these locations, S. apetala exhibits invasive characteristics such as overgrowth and high spreading ability that evidently affects local mangrove ecosystem structure and function. While the species clearly offers some benefits at some locations where it cannot naturally invade, it appears harmful to other native mangrove species, posing a major practical problem to both ecologists and land managers. This situation will be similar to previously imported non-native and invasive intertidal wetland species, Spartina alterniflora (smooth cordgrass), with similar results and problems. 相似文献
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Sexual cannibalism in scorpions: fact or fiction? 总被引:2,自引:0,他引:2
ALFREDO V. PERETTI LUIS E. ACOSTA TIM G. BENTON 《Biological journal of the Linnean Society. Linnean Society of London》1999,68(4):485-496
Females of several scorpion species are currently deemed to be sexual cannibals, but this reputation is, however, largely built on anecdotal evidence from the older literature. Theoretical models predict that given the low rates of female-male encounter, males should allow themselves to be cannibalized after sperm transfer. The present paper examines the information available for a number of species to determine (a) whether sexual cannibalism is as widespread as previously suggested, and (b) whether it is likely to involve male self-sacrifice. Information on three scorpions currently regarded as sexual cannibals is presented: the bothriurids Bothriurus bonariensis (C.L. Koch) and Urophonius jheringii Pocock, and the buthid Leiurus quinquestriatus (Hemprich & Ehrenberg). No post-mating cannibalism was ever observed in these species, nor in another 19 representatives of four families. In L. quinquestriatus only two cases of cannibalism of the male by the female occurred, both in the beginning of courtship and after long periods of food deprivation. We suggest that if sexual cannibalism occurs in scorpions, it is most likely to be of an 'economic' type, where females perceive males as prey rather than mates, and not a 'self-sacrificial', post-mating cannibalism enhancing the fitness of the offspring of the male. 相似文献