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《仿生工程学报(英文版)》2006,3(4):F0003-F0003
The Journal of Bionic Engineering publishes original research papers and reviews on all aspects of bionic science and engineering including fundamental understandings of animals and plants for bionic engineering, such as locomotion and behaviors of animals, structures, composites, morphology and physical properties of plants and natural materials, applications of such understandings in engineering, technology and designs. 相似文献
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《分子细胞生物学报》2006,(5)
One of the highest-ranking journals In biology with an Impact factor of 6.787! BioEssays Editor: Adam S. Wilkins, Cambridge, UK BioEssays offers readers in-depth review articles and serves as a resource for education and new ideas by exploring a wide range of biological topics. Researchers and teachers are presented with a unique tool for learning how findings in molecular, cellular, 相似文献
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Herbert J. Paterson 《BMJ (Clinical research ed.)》1912,1(2681):1158-1159
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PartlissubdividedintotWollthofaed,Whichcomrisefluvial-lacustrinandfissure-cavemlahons'Fluvial-laCUStrinetritSdopoaitalinthelowerpartoftheriverchannels,basinsorplain;fissare-cavendbotSexPondonlyinthemountaintriin,wherePartIisabout5-8mmickandharsmammalfotalsSUchasbooridaefeen'etrp.indot.),MbonasP.,lycbotessineasis,cfMthechtai,FelissP-,Archhaplandna,Cervche,andColubdee'ItmaybeconsideredtobeearlyPleistocene'Partnismorethan2OInmick'ThefadesofPartIIcomrisealluvial-laCUStrineandfise-caved… 相似文献
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《Nucleosides, nucleotides & nucleic acids》2013,32(5-7):651-654
The expression “universal base” is very often used to express hybridization properties and recognition patterns of nucleosides. Their behaviour in biological applications, however, is of great interest regarding, e.g., their incorporation by polymerases. The 4,6-difluorobenzimidazole and the 2,4-difluorobenzene nucleoside analogues have proven to be universal bases that do not discriminate between the four natural nucleobases in RNA duplexes. Therefore, we synthesized the corresponding triphosphates to evaluate their behavior in polymerase catalyzed reactions and to investigate their ability to serve as substrates for the T7 RNA polymerase. 相似文献
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《Nucleosides, nucleotides & nucleic acids》2013,32(5-7):533-537
N4-Acetyl-1-(2, 3-di-O-acetyl-4-thio-β-D-arabinofuranosyl)cytosine (2) was synthesized in three steps from 1-(4-thio-β-D-arabinofuranosyl)cytosine (1). The reaction of this partially blocked 4′-thio-ara-C derivative 2 with 2-chloro-4H-1,3,2-benzodioxaphosphorin-4-one gave the 5′-phosphitylate derivative 3, which on reaction with pyrophosphate gave the 5′-nucleosidylcyclotriphosphite 4. Product 4 was then oxidized with iodine/pyridine/water and deblocked with concentrated ammonium hydroxide to provide the desired 4′-thio-ara-C-5′-triphosphate 5. This triphosphate 5 was converted to 4′-thio-ara-C -5′-monophosphate 6 by treatment with snake venom phosphodiesterase I. The details of the synthesis, purification, and characterization of both nucleotides are described. 相似文献