Meeting Report: 1st International Symposium on Sponge Microbiology

The success of the 1st International Symposium on Sponge Microbiology reflects the growing interest of the scientific community in this new and emerging field. Research themes of the symposium included symbiont diversity, physiology and function, secondary metabolites, metagenomics, single-cell genomics and other -omics approaches, sponge–symbiont interactions, sponge diseases, environmental stress, and many more. This article summarizes the major developments in the field and identifies future foci for research.     

第九届韩中菌物学学术讨论会

<正>时间:2009年10月21日至10月25日地点:韩国首尔,Seoul/Hotel-Seoul Kyoyuk Munhwa Hoekwan国外邀请单位、邀请人和详细地址(外文):Prof.Kyu Joong Kim(kyujkim@kangnung.ac.kr),President of the Korean Society of Mycology,Kangnung National University会议发起组织:中国菌物学会,韩国菌学会The Mycological Society of China(MSC),The Korean Society of Mycology(KSM)会议主办单位:韩国菌学会,The Korean Society of Mycology(KSM)会议语言:英语会议主要内容:本次会议将采用大会报告、墙报等多种形式进行学术交流。大会报告约40人,报告内容将涉及菌物资源、菌物多样性;真菌的分类、鉴定及系统学;应     

Meeting Report

Syntaxin 10 is a soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) protein localized to the trans-Golgi network (TGN), where two other members of the syntaxin family, syntaxins 6 and 16, also reside. The role of syntaxin 10 in regulating TGN protein traffic is not yet defined. Syntaxin 10 co-localizes well with syntaxins 6 and 16 at the TGN in interphase cells, and appears to interact with both syntaxin 6 and 16 as evidenced by co-immunoprecipitation analyses. However, unlike syntaxin 6 and 16, neither syntaxin 10 antibodies nor its cytosolic domain inhibits endosome-TGN transport of shiga toxin. Syntaxin 16 knockdown with small interfering RNA (siRNA) affects the TGN localization of syntaxin 6 but not syntaxin 10, and clearly inhibits endosome-TGN transport. On the other hand, knockdown of syntaxin 10 expressions had no significant effect on the TGN localization of syntaxin 6 and 16, and did not inhibit endosome-TGN transport. Unlike syntaxin 16, syntaxin 10 does not interact specifically with Vps45, the Sec1/Munc18 (SM) family member at the TGN. On the other hand, syntaxin 10 reciprocally co-immunoprecipitated endosomal syntaxin 12/13, and knockdown of syntaxin 10 expressions affects the surface expression of transferrin receptor (TfR) and seems to induce the formation of an immobile TfR pool. Therefore, in spite of its co-localization and possible interaction with syntaxin 16, syntaxin 10 is not part of the syntaxin 16-based SNARE complex involved in endosome-TGN transport, and may have a hitherto unrecognized function in the TGN-endosome boundary.     

The 2011 Joint Sino-U.K. Protein Symposium

As part of the celebrations marking its Centenary, the Biochemical Society held a joint meeting in Shanghai with the Chinese Protein Society to commemorate the many long-standing collaborations between biochemists from the U.K. and China. Under the overall theme of structural biology of proteins, presentations covering both historical and current research were given by a number of leading biochemists from both countries. Papers based on these talks have been prepared for this issue of Biochemical Society Transactions.